Streptomyces roseirectus: IAG44_27095
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Entry
IAG44_27095 CDS
T07860
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sroi
Streptomyces roseirectus
Pathway
sroi00790
Folate biosynthesis
sroi01100
Metabolic pathways
sroi01240
Biosynthesis of cofactors
Module
sroi_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
sroi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
IAG44_27095
Enzymes [BR:
sroi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
IAG44_27095
6.3.2.17 tetrahydrofolate synthase
IAG44_27095
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QNP72729
UniProt:
A0A7H0IIW3
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All DBs
Position
6330088..6331575
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AA seq
495 aa
AA seq
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MTDSDPFDEIIAAETDRDPDLAVIEAGSRTLRTQGAGQAQADVPARPADPEVEKALREVE
TELATRWGETKLEPSVKRIAALMDVLGEPQNAYPSIHVTGTNGKTSTARMIESLLGAFEL
RTGRYTSPHVQSITERISLDGAPLSAERFVETYQDIKPYVEMVDAQQEFRLSFFEILTAM
AYAAFADAPVDVAVVEVGMGGTWDATNVIDADVAVITPISLDHTDRLGSTPAEIAGEKGG
VIKADATVILAQQPVDAAQVLLKRAVEVDATVAREGLEFGVVERQVAVGGQLMTLRGLGG
EYPEVFLPLHGAHQAHNAAVALAAVEAFFGVGAARAEPLDLDVVRKAFAAVTSPGRLEVV
RRSPTVVLDAAHNPAGARVTADAISEVFDFSRLIGVVGASGDKDVRGLLEAFEPIFAEIV
VTQNSTARAMDADELAAIAVEVFGEDRVQVEPRLPDALEAAITLAEEDGEFSGGGVLVTG
SVITVGEARVLLGGR
NT seq
1488 nt
NT seq
+upstream
nt +downstream
nt
gtgacagacagcgacccgttcgacgagatcatcgccgccgagaccgaccgtgaccccgac
ctcgcggtcatcgaggcggggagccgcacactccgcacccaaggcgcgggccaggcccag
gccgacgtcccggcacgccccgcggaccccgaggtcgagaaggctctgcgcgaggtcgag
acggagctggccacgcgctggggcgagacgaagctggagccgtcggtcaagaggatcgcc
gcgctgatggacgtcctgggggagccccagaacgcgtacccgtcgatccacgtcacgggc
acgaacggcaagacgtccacggcccgcatgatcgagtcgctgctcggcgcgttcgaactg
cgcaccggccgctacacgtccccccacgtccagtcgatcaccgaacgcatcagcctggac
ggcgcccccctctcggcggagcgcttcgtcgagacgtaccaggacatcaagccgtacgtc
gagatggtcgacgcccagcaggagttccgcctctccttcttcgagatcctgacggccatg
gcgtacgcggcgttcgcggacgccccggtggacgtcgcggtcgtcgaggtcggcatgggc
ggcacctgggacgcgacgaacgtgatcgacgcggacgtcgccgtgatcacccccatctcc
ctggaccacacggaccgcctgggctccacccccgccgagatcgccggcgagaagggcggc
gtcatcaaggcggacgcgacggtgatcctggcccagcagccggtggacgccgcgcaggtc
ctgctgaagcgcgcggtcgaggtcgacgcgacggtcgcgcgcgagggcctggagttcggg
gtcgtcgagcggcaggtcgccgtcggcggccagctgatgaccctgcggggcctgggcggc
gagtaccccgaggtcttcctcccgctgcacggcgcccaccaggcgcacaacgcggccgtg
gccctcgccgccgtcgaggcgttcttcggcgtcggcgccgcccgcgcggaacccctcgac
ctcgacgtcgtccgcaaggcgttcgcggccgtcacctcgccgggccgcctggaggtcgtc
cgccgctcgccgacggtcgtcctggacgccgcgcacaacccggcgggcgcgcgcgtgacg
gccgacgcgatcagtgaggtgttcgacttcagccggctcatcggcgtcgtcggcgcgagc
ggcgacaaggacgtccgggggctcctggaggcgttcgagccgatcttcgcggagattgtc
gtcacgcagaactcgacggcgcgcgcgatggacgcggacgagctggcggcgatcgccgtc
gaggtcttcggcgaggaccgcgtccaggtcgaaccccgcctccccgacgccctggaggcc
gcgatcacgctggccgaggaggacggcgagttctccggcggcggcgtgctggtcaccggt
tccgtcatcaccgtgggcgaggcccgcgtgctgctgggaggtcgctga
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