KEGG T01009: 100620470

Sus scrofa (pig): 100620470

Entry

100620470         CDS       T01009

Name

(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 6

K13369

17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]

Organism

ssc Sus scrofa (pig)

Pathway

ssc00140

Steroid hormone biosynthesis

ssc00830

Retinol metabolism

ssc01100

Metabolic pathways

ssc01240

Biosynthesis of cofactors

Module

ssc_M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

ssc_M00977

C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone

Brite

KEGG Orthology (KO) [BR:ssc00001]
09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100620470
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    100620470
Enzymes [BR:ssc01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     100620470
    1.1.1.105  all-trans-retinol dehydrogenase (NAD+)
     100620470
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     100620470

SSDB

Motif

Pfam:

adh_short adh_short_C2 DUF1776 KR

Other DBs

NCBI-GeneID:

100620470

NCBI-ProteinID:

XP_003355507

Ensembl:

ENSSSCG00000027854

UniProt:

A0A8D1CFQ7 A0A4X1W6H0

LinkDB

Position

5:22089496..22114319

AA seq 317 aa
MWLYLAVLVGLYYLLRWYRERQMVSHLGDKYVFITGCDSGFGNLLARQLDVRGLRVLAAC
LTEQGAQQLRKQTSDRLETVLLDVTKTESIAAATQWVKERVGDRGLWGLVNNAGTFHPLC
ITEWLKTETWIHTLKVNLIGVTEVTLSMLPLVKKAQGRIVNVSSILGRVAFFGAVYSSSK
HGVEAFSDVLRCELQHFGVKVSIVEPGYFRTGMTDVQKSSEAMKQVWKEVPAHIKDTYGQ
KFFDAYHDVMKQGLSSCSTNLNLVTDCMEHALTSVHPRTRYSAGWDAQFFFIPLSYLPTS
LADYILTRSWPKPVQAV

NT seq 954 nt +upstreamnt +downstreamnt
atgtggctgtacctggctgtcctcgtgggcctgtactacctccttcgctggtaccgggaa
aggcagatggttagccaccttggggataagtatgtcttcatcacgggctgtgactcgggc
tttgggaacctgctggcgaggcagctggatgtgaggggcttgagggtcctggctgcatgt
ctgacggagcagggggcccagcagctgaggaagcagacgtcagacaggctggagacggtg
ctcttggacgtgaccaagacagagagcattgctgcggccacccagtgggtgaaggagcgt
gtcggggacagaggactctggggtctggtcaacaatgcaggcacttttcacccactgtgc
atcactgagtggctgaagactgagacctggatacataccctcaaagtgaacctcattggt
gtgacagaggtgaccttgagcatgcttcccttggtgaagaaagcacaggggagaattgtc
aatgtctccagcattctgggaagagttgctttctttggagcagtctactctagctccaag
catggagtggaagccttttcagatgtcctgagatgtgagcttcagcattttggggtgaaa
gtcagcatagttgaacctggttacttcagaacaggaatgacagatgtgcagaagtcctca
gaggcaatgaagcaagtctggaaagaagtccctgctcatattaaggacacctatggacag
aagttttttgatgcctatcacgatgttatgaaacaagggctgtctagttgtagcacaaac
ctgaacctggtcacggactgcatggaacacgctctgacatctgtgcatccccgcactcgg
tactcagctggctgggatgctcaatttttcttcatccctctgtcttatttacctacatca
ctggcagactacatactgactagatcttggcccaaaccagtgcaggcagtctaa

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