KEGG   Sus scrofa (pig): 445522
Entry
445522            CDS       T01009                                 
Symbol
TPO
Name
(RefSeq) thyroid peroxidase
  KO
K00431  thyroid peroxidase [EC:1.11.1.8]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00350  Tyrosine metabolism
ssc01100  Metabolic pathways
ssc04918  Thyroid hormone synthesis
ssc05320  Autoimmune thyroid disease
Module
ssc_M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    445522 (TPO)
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    445522 (TPO)
 09160 Human Diseases
  09163 Immune disease
   05320 Autoimmune thyroid disease
    445522 (TPO)
Enzymes [BR:ssc01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.8  iodide peroxidase
     445522 (TPO)
SSDB
Motif
Pfam: An_peroxidase Sushi EGF_CA EGF_3 EGF LRRNT FXa_inhibition
Other DBs
NCBI-GeneID: 445522
NCBI-ProteinID: NP_001171681
Ensembl: ENSSSCG00000025035
UniProt: D6NHN4
LinkDB
Position
3:complement(132384677..132409750)
AA seq 754 aa
MGARAVLGVTLAVACAGAFFASILRRKDLLGGDTEASGVAGLVEASRLLVDEPIHTTMRR
NLRKRGIFSPSQLLSFSKLPEPTSRTASRAAEIMETAVQEVKRRVCRRRDTDELPTDVLS
EELLSTMANLSGCLPHMLPASSPHTCLANKYRLITGACNNRDHPRWGASNTALARWLPPA
YEDGVTEPRGWNPHFLYNGLPLPPVREVTRQVIHVSNEAVTEDGQYSDLLMAWGEYIDHD
IAFTPQSTSKAAFAGGADCQLTCENRSPCFPIQIVTLRDYVPKILGAEAFGQHVGPYQGY
DPAVDPTVSNVFSTAAFRFGHATIHPLVRTLDARFQEHPGSHLPLRAAFFQPWRLLREGG
VDPVLRGLLARPAKLQVQDQLMNEELTERLFVLSNSGTLDLASINLQRGRDHGLPGYNEW
REFCGLSRLETWADLSAATANGRVADRILGLYQHPDNIDVWLGGLAESFLPGARTGPLFA
CIIGKQMRALRDGDRFWWENPGVFTEAQRRELSRHSMSRVICDNSGLSHVPLDAFRVGQW
PQEFEPCASIQGMDLGAWREAPPSGDACGFPDPVEDGGFLLCEERGQRVLVFSCRHGFRL
RGPAQITCTPRGWDSPPPLCKDINECEDETDPPCHASARCKNTKGGVLCECSDPLVLGED
GRTCVDAGRLPRASVVSIALGAVLVCGLAGLAWTVVCRWTHADARPLLPVGEGEGDGKSP
SLPLPGCGNRRDVGAAPALEVEQDLSCGSRGLCE
NT seq 2265 nt   +upstreamnt  +downstreamnt
atgggggcgcgggccgtcctgggcgtcacgctggccgtggcctgtgcaggagctttcttc
gcatccatcctgagacgaaaggacctccttgggggggacacggaggcatctggcgtcgcg
ggcctcgtggaggcgagcaggctcctggtggacgagcccattcacaccacgatgagaaga
aacctccgcaagagggggatcttctccccgtcgcagcttctgtccttttccaaactccct
gagcccacaagccgcacagcatcccgggcggcggagatcatggagacggcggtccaggag
gtgaagaggagggtttgccgcaggcgagacactgacgagctccccacagacgttttatca
gaagagctcctgagcacgatggcaaacctgtcgggctgcctgccccacatgctgcccgcc
agctctccccacacctgcctggccaacaagtaccggctcatcacgggcgcctgcaacaac
agagaccaccccaggtggggcgcctccaacacagccctggccaggtggctgccccccgcc
tacgaggacggtgtcactgagccccgaggctggaacccccacttcctgtacaacgggctc
ccgctgcccccggtccgggaggtgaccagacaagtcatccacgtttccaatgaggctgtt
acggaggacggccagtattctgacctcctgatggcgtggggggagtacatcgaccacgac
atcgccttcacgccgcagagcaccagcaaggcggccttcgcgggcggagccgactgccag
ctgacctgcgagaaccgcagtccgtgctttcccatacagatcgtcaccctgcgggattac
gtccccaaaatcctgggcgccgaggcctttgggcagcacgtgggcccttaccagggctac
gaccccgccgtggaccccactgtgtccaacgtgttctccacggccgccttccgcttcggc
cacgccacgatccacccgctggtgcggacgctggacgcacgattccaggaacacccgggc
tcccacctgccactgcgggctgccttcttccagccctggaggctcctgcgagaaggtggt
gtggaccccgtcctgaggggcctgctggccagaccagccaagctgcaggtgcaggaccag
ctgatgaacgaggagctcacagagaggctcttcgtgctgtcgaactcggggaccttggac
ctggcctccatcaacctgcagaggggccgggaccacggccttccaggttacaacgagtgg
agagaattctgcggcctgtccagactcgagacctgggccgacctgagtgctgccactgcc
aacgggcgtgtggccgacaggatcctgggcctgtaccagcatccggataacattgacgtc
tggctgggcggcttggccgagagcttcctccctggggcgcggaccggcccgctgttcgcc
tgcatcatcggaaagcagatgagggccctgagggacggcgaccggttctggtgggagaac
ccgggggtgttcacagaagcccagaggcgcgagctgagccggcactctatgtcccgcgtc
atctgcgacaacagcggcctgtcccacgtgccccttgatgccttccgggtgggccagtgg
cctcaggagttcgagccgtgtgccagcatccagggcatggacctgggcgcgtggagggag
gcccctccgtcaggggacgcgtgtggcttcccggacccagtggaagacgggggcttcctg
ctctgtgaggagcgtggccagcgcgtgctggtgttttcctgtcgtcacgggttccggctc
cgaggaccagcgcagatcacctgcaccccccgagggtgggactccccgccccccctctgt
aaagacatcaacgagtgtgaagacgagacagaccctccctgccacgcgtctgcccggtgc
aagaacaccaagggtggcgtcctgtgcgagtgctcggaccctctcgtgctcggggaggac
ggcaggacctgcgtggatgccgggaggctcccgcgggcgtctgtggtctccatcgcgctg
ggcgccgtgctcgtctgcggcctcgcaggcctcgcctggacggtggtttgcaggtggaca
cacgcggatgccaggcccttgctgcccgtcggggagggagaaggagacgggaaaagcccc
tccctgccgctgccgggatgcgggaaccgccgggatgtgggcgctgctcccgctctggag
gtggagcaggacctgagctgtggatcccgaggcctctgcgagtag

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