Sporothrix schenckii: SPSK_04991
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Entry
SPSK_04991 CDS
T05555
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
ssck
Sporothrix schenckii
Pathway
ssck00270
Cysteine and methionine metabolism
ssck00480
Glutathione metabolism
ssck01100
Metabolic pathways
ssck01240
Biosynthesis of cofactors
Module
ssck_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ssck00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SPSK_04991
09106 Metabolism of other amino acids
00480 Glutathione metabolism
SPSK_04991
Enzymes [BR:
ssck01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
SPSK_04991
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
zf_topless
Motif
Other DBs
NCBI-GeneID:
27667025
NCBI-ProteinID:
XP_016583831
UniProt:
A0A0F2LXC8
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All DBs
Position
Unknown
AA seq
719 aa
AA seq
DB search
MGLLQLGTALDWPEAKAHADQVRKWGIKQLLEIWNKAKTKERDALLWGDEVEYLVVTYDK
DDPRSLLSLRQADILDALANDAVLAAKGGCTEGQADVTDAAGNKSNQDPLPVFHPEFGRF
MLESTPGKPWGIELKELIDVEPNMRLRRVIAKDHMRSDEYPITLTTFPRLGFPGVFSDPY
YPVSGPKLRSQFVPDEIANPHIRFPTLAANIRTRRGRKVQVNVPVFRDVNTPWPWKDPTV
NYDLNKYPEDADVRNGSAPDNFIHMDAMAFGMGSCCLQITFQAKNITEGRRLYDQLSPLG
PILLALTAATPIYKGFLADTDVRWNQISRAVDDRTPEELGEKPLKNDRWRIPKSRYASNS
TYISTDPRLRPEYLDPDLVVDEEIKAELIQGGMDDRLATHFAHLFIRDPIVIFSEDLQTL
DLDQTNHFENLQSTNWQHMRFKPPPPDNSIGWRVEVRPMEVQVTDFENAAFAVFIVLVTR
AILSFDLNFYIPIARVTENMETAHARDAVLNERFYFRKNLFNAQRAHRYGRHRSPHGDDT
NSAYASGTTTPVAQSRPETPVALGSVEDEYRPMTINEIINGTGYPMYGADNDDQSNGEPA
SSPADPPFPGLIPLVESYLDSMNVDVQTRCQLSTYLDLIRKRASGELWTAARWLRSYVDQ
HPEYKHDSAVSELVTRDIVGAVIDIGKRETDGAGWKGMNVPGVDRLLGDFSGCGGDVKC
NT seq
2160 nt
NT seq
+upstream
nt +downstream
nt
atgggtctcttacagctcggcacggcattggattggccggaagccaaggcgcacgctgac
caggtccgcaaatggggcatcaagcaactcctcgagatctggaacaaggccaagacgaaa
gagagggacgccctgctctggggcgacgaggttgagtatctcgttgtgacgtatgacaag
gatgatcctcgatcacttctgtctctgcgccaggccgacatcctcgatgccctggccaac
gacgctgtcctggcagccaagggcggctgcacagaaggccaggctgacgtcacagatgct
gccgggaacaagtccaaccaagacccgctgccggtcttccatcccgagttcggccggttc
atgctcgaatcgacaccgggtaaaccgtggggcattgagctgaaggagctcatcgacgtc
gagcctaacatgcggctacggagagtcattgccaaagaccacatgcgttccgacgagtac
ccaatcaccctgacgacgttcccgcgactggggttcccaggcgtgttttcggacccgtat
taccccgtgtcgggccccaagctacggtcacaattcgtgccagatgaaattgccaacccg
cacatacgcttcccgacgcttgccgccaacatccgcacgcgccgcggccgcaaggtccag
gtcaacgtgcccgtctttcgcgatgtgaacacaccctggccgtggaaggacccaactgtc
aactacgacctcaacaagtaccccgaagatgccgacgtgcgcaatggttccgctccggac
aacttcatccacatggatgctatggcgtttggtatgggcagctgctgcttgcagatcacc
ttccaggccaagaacatcaccgagggccgtcggctctacgaccagctcagtcctctgggg
cccatcctgttggcgctgacggcggcgacaccaatctacaagggctttttggccgatacg
gacgtgcgctggaaccaaatcagccgcgccgtggacgaccgcacaccggaagagctcgga
gagaagccgctgaagaatgaccgctggcggataccaaagtctcggtacgcgtccaattca
acgtacatctcgaccgacccgcggctgcggcctgaatacttggacccggaccttgtggtc
gatgaggaaatcaaggcggagctgatccagggcggcatggatgaccgcctggcgacgcac
tttgcgcacctgttcatccgcgacccgattgtcatcttctccgaggacctgcagacgctc
gacctggaccagacgaaccactttgaaaacctgcagtcgaccaactggcaacacatgcgc
ttcaagccgccgccgccagacaatagcattggatggcgtgttgaggtgcggcccatggag
gtgcaggtcaccgactttgagaacgccgcgtttgccgtcttcattgtgcttgtgactcgt
gccatcctgtcatttgacctcaacttttacatccccattgcacgtgtgacagagaacatg
gagacggcacatgcgcgtgacgccgttttgaacgagcggttttacttccggaagaacctc
tttaatgcgcaacgggcccatcggtatggccgccatcggtcgccacacggcgacgacaca
aatagtgcctacgcctcaggcacaacgacgcccgtcgcacagagccggccggagacgcct
gtagcgttgggctccgtggaggacgagtaccggccaatgacgatcaatgagattataaac
ggcaccggatatccaatgtacggcgccgacaacgacgaccaatcgaatggcgagcctgcg
tcgtcaccggctgaccctcccttccccggcctcatcccgctcgtcgaaagctacctcgac
tccatgaacgtcgacgtgcagacgcgctgtcaactgtccacatacctcgaccttatccgt
aagcgcgcatccggcgagttgtggacggccgcccgctggcttcggtcgtacgtcgaccag
catcccgagtacaagcacgatagtgcagtctcagagcttgtgacccgggacattgtcggt
gccgtcattgacattggtaaacgtgagacggatggtgcaggttggaagggcatgaatgta
ccaggagtcgaccggctactgggcgactttagtggttgcggcggggatgttaaatgctag
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