Streptomyces subrutilus: CP968_22110
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Entry
CP968_22110 CDS
T07087
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ssub
Streptomyces subrutilus
Pathway
ssub00790
Folate biosynthesis
ssub01100
Metabolic pathways
ssub01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ssub00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CP968_22110
Enzymes [BR:
ssub01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CP968_22110
6.3.2.17 tetrahydrofolate synthase
CP968_22110
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QEU80622
UniProt:
A0A5P2UMX5
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Position
4998709..5000238
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AA seq
509 aa
AA seq
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MSEQQPESHGPDDLDHRLDEFDQIVAEESERDPDLAVIEAGSRTLRALAGPPQGDAVPAH
PTDPEVARALLEVEQELATRWGETKLEPSVSRIAALMDVLGEPQRAYPSVHVTGTNGKTS
TARMIECLLNAFELRTGRYTSPHVQSVTERISLDGAPISAERFVETYHDIKPYVEMVDAA
EEYRLSFFEVLTGMAYAAFADAPVDAAVVEVGMGGTWDATNVIDGSVAVVTPISLDHTDR
LGSTPGEIAGEKGGVIKQGATVILAQQPVDAAQVLLKKAVEVDATVAREGMEFGVVSREV
AVGGQQLTLRGVGGEYDGIFLPLYGAHMARNAAVALAAVEAFFGIGQEHARALDVETVRK
AFASVTSPGRMEVVRRSPTVVLDAAHNPAGAAATAEAVTESFGFSRLVGVVAASEGKDVR
GVLEAFEPIFAEVVVTENSSHRSMGADELAGVAVEVFGADRVQVEPRLDDALEAAITLAE
EEAEYGGAGVLVTGSVITVGEARLLMKRG
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagcagcagcccgagagccacggccccgacgatcttgaccaccgtctcgacgag
ttcgaccagatcgtggcggaggagtccgagcgcgaccccgacctggcggtgatcgaagcc
gggagccgcaccctgcgcgccctggccggcccgccgcagggggacgccgtacccgcgcac
cccaccgacccggaggtcgcccgggcgctcctggaggtggagcaggagctcgccacccgc
tggggcgagacgaagctggagccgtcggtgtcgcgcatcgcggcgctgatggacgtcctg
ggggagccgcagcgcgcgtacccctccgtccacgtcaccggcacgaacggcaagaccagc
acggcccgcatgatcgagtgcctgctgaacgccttcgagctgcgcaccggccgctacacg
agcccgcacgtccagtcggtcaccgagcggatcagcctcgacggtgcgccgatcagcgcc
gagcggttcgtggagacataccacgacatcaagccgtacgtggagatggtcgacgccgcc
gaggagtaccggctgtcgttcttcgaggtgctgaccgggatggcgtacgccgccttcgcg
gacgctccggtcgacgcggccgtggtcgaggtcggcatgggcggcacctgggacgcgacc
aacgtgatcgacggctcggtcgcggtggtcaccccgatcagcctggaccacaccgaccgg
ctcggctccacccccggtgagatcgccggggagaagggcggggtcatcaagcagggcgcc
accgtgatcctcgcgcagcagccggtggacgcggcgcaggtgctgctgaagaaggccgtc
gaggtcgacgcgaccgtggcccgcgagggcatggagttcggcgtcgtctcgcgcgaggtc
gcggtcggcggccagcagctgacgctgcgcggcgtgggcggcgagtacgacgggatcttc
ctgccgctgtacggggcgcacatggcgcgcaacgcggcggtggcgctggccgcggtcgag
gccttcttcggcatcggccaggagcacgcacgggcgctggacgtggagaccgtgcggaag
gccttcgcctcggtgacctcgccgggccgcatggaggtcgtgcggcgcagcccgacggtg
gtcctggacgcggcgcacaacccggcgggcgcggcggccaccgcggaggcggtcacggag
tcgttcggcttcagccgcctggtcggggtcgtcgccgcgagcgagggcaaggacgtgcgc
ggggtgctggaggccttcgagcccatcttcgccgaggtggtggtgacggagaactccagc
caccggtcgatgggcgcggacgagctggcgggcgtcgccgtcgaggtgttcggtgcggac
cgggtgcaggtggagccgcggctggacgacgccctggaggcggcgatcaccctggcggag
gaagaggccgagtacggaggggccggggtcctggtgaccggttccgtgatcacggtgggc
gaggcccgcctgctgatgaagaggggctga
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