Streptomyces sp. SirexAA-E: SACTE_4509
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Entry
SACTE_4509 CDS
T01601
Name
(GenBank) 2-oxoglutarate dehydrogenase, E1 subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
ssx
Streptomyces sp. SirexAA-E
Pathway
ssx00020
Citrate cycle (TCA cycle)
ssx00630
Glyoxylate and dicarboxylate metabolism
ssx00785
Lipoic acid metabolism
ssx01100
Metabolic pathways
ssx01110
Biosynthesis of secondary metabolites
ssx01120
Microbial metabolism in diverse environments
ssx01200
Carbon metabolism
ssx01210
2-Oxocarboxylic acid metabolism
Module
ssx_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ssx_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ssx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SACTE_4509
00630 Glyoxylate and dicarboxylate metabolism
SACTE_4509
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SACTE_4509
Enzymes [BR:
ssx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SACTE_4509
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SACTE_4509
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SACTE_4509
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SACTE_4509
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
2-oxoacid_dh
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AEN12339
UniProt:
G2NM62
LinkDB
All DBs
Position
complement(4978374..4982216)
Genome browser
AA seq
1280 aa
AA seq
DB search
MSSQSPSNSSISTDQEAGSGSNPAAAFGANEWLVDEIYQQYLQDPSSVDRAWWDFFADYK
PGTSGTADKPVPATAGAAVTPAPAAGTANNTPAAAPAPAKAAAPSSAPASPAKAAPAAAP
AKPAAAQAAPAKAAPAKAAPAKAAPAAEKKADDATEAPAGPEYVTLRGPSAAVAKNMNAS
LELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQALKAMPSMNHSF
AVKDGKPTLVKPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRAR
VGKLGMDDFTGVTASLTNPGGIGTVHSVPRLMPGQGLIMGVGAMDYPAEFQGTSQDTLNK
LGISKVMTLTSTYDHRVIQGAASGEFLRVLAQLLLGENDFYDEIFKALRIPYEPVRWLKD
IDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLERD
FAVGGFAGKTMMKLRDILGVLRESYCRTTGIEFMHIQDPKERKWIQDRVERPRPAPEREE
QLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAEARLDEVVIGMA
HRGRLNVLANIVGKSYAQIFREFEGNLDPRSMHGSGDVKYHLGAEGTFTGLDGEQIKVSL
AANPSHLEAVDPVLEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQL
RGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPEAVVRVARL
AFEYRQTFNKDVVIDLICYRRRGHNEGDNPEFTNPQMYTLIDKKRSVRKLYTESLIGRGD
ITLEEAEQALQDFQGQLEKVFAEVREATSAPSQPHVPDVQAEFPVAVNTAVSSEVVKLIA
ESQVNIPDTVTVHPRLLPQMQRRASSVENGTIDWGMGETLAIGSLLMEGTPVRLAGQDTR
RGTFGQRHAVLVDQKTGEDYTPLLYLSEDQARYNVYDSLLSEYAAMGFEYGYSLARPESL
VIWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQ
MCAQDNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKVEEFTTGGF
RPVIGDDSVEAEAVRKVVFCAGKLFYDLDAERVKRGDTETAIIRLERLYPLPGAEIQAEI
AKYPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAV
GSAKRHQAEQTQLIDEVFEA
NT seq
3843 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactcgagtatctcgaccgatcaagaagcgggctccggg
tccaacccggcggccgctttcggtgccaatgagtggctcgtcgacgagatctaccagcag
tacctccaggatcccagttcggtcgaccgcgcctggtgggacttcttcgccgactacaag
ccgggcacgtccggcacggcggacaagcccgttcccgcgacggcgggtgccgcggtgacc
ccggctccggccgcgggcaccgcgaacaacaccccggccgccgcgcccgctccggccaag
gccgcggccccctcgtccgcccccgcctccccggcgaaggcagccccggcggccgcaccc
gcgaagcccgccgccgcgcaggccgctccggcgaaggccgcccccgccaaggcggccccg
gcgaaggcggctccggccgccgagaagaaggccgacgacgcgaccgaggccccggccggc
cccgagtacgtgacgctgcgcggcccctcggccgccgtcgcgaagaacatgaacgcctcg
ctggagctgccgacggccacgtccgtccgcgcggtcccggtgaagctgctgttcgacaac
cgcatcgtcatcaacaaccacctcaagcgcgcccgcggcgggaagatctccttcacgcac
ctcatcgggtacgcgatggtgcaggccctcaaggccatgccgtcgatgaaccactccttc
gcggtcaaggacggcaagccgaccctggtcaagccggagcacgtcaacctcggcctcgcc
atcgacctggtgaagccgaacggcgaccgccagctggtcgtcgcggccatcaagaaggcc
gagacgctcaacttcttcgagttctggcaggcgtacgaggacatcgtccgccgcgcccgt
gtcggcaagctcggcatggacgacttcaccggtgtcaccgcctcgctgaccaaccccggc
ggcatcggcaccgtgcactcggtgccccgcctgatgcccggacagggcctcatcatgggc
gtcggcgcgatggactacccggccgagttccagggcacctcgcaggacaccctgaacaag
ctgggcatctccaaggtcatgacgctgacctcgacgtacgaccaccgggtcatccagggt
gcggcgtccggcgagttcctccgcgtcctggcccagctcctgctcggcgagaacgacttc
tacgacgagatcttcaaggcgctgcgcatcccctacgagccggtccgctggctcaaggac
atcgacgcctcgcacgacgacgacgtcaccaaggccgcgcgggtcttcgagctgatccac
tcctaccgggtccggggccacgtcatggccgacaccgacccgctggagtaccgccagcgc
aagcaccccgacctggacatcaccgagcacggcctcaccctgtgggacctggagcgggac
ttcgcggtcggcggcttcgccggcaagacgatgatgaagctccgcgacatcctcggcgtc
ctgcgtgagtcgtactgccgcaccaccggcatcgagttcatgcacatccaggacccgaag
gagcgcaagtggatccaggaccgggtggagcgtccgcgcccggccccggagcgtgaggag
cagctgcggatcctgcgccgcctcaacgccgccgaggcgttcgagacgttcctgcagacc
aagtacgtcggtcagaagcggttctcgctggagggcggcgagtccgtcatcccgctgctc
gacgcggtcatcgactccgcggcggaggcgcgcctggacgaggtcgtcatcggcatggcc
caccgcggccgtctgaacgtcctggcgaacatcgtcggcaagtcgtacgcgcagatcttc
cgggagttcgagggcaacctcgacccgcggtcgatgcacggctccggcgacgtcaagtac
cacctgggcgccgagggcaccttcaccggtctggacggcgagcagatcaaggtctcgctg
gccgccaacccctcgcacctggaggcggtcgacccggtcctggagggcatcgcccgcgcc
aagcaggacatcatcaacaagggcggtacggacttcacggtcctgcccgtcgcgctccac
ggcgacgcggccttcgcgggccagggtgtcgtcgcggagacgctcaacatgtcgcagctg
cgcggttaccgcaccggcggcaccgtgcacgtggtgatcaacaaccaggtcggcttcacc
gccgcaccggagtcctcgcgctcctcgatgtacgccaccgacgtggcgcgcatgatcgag
gcgccgatcatccacgtcaacggcgacgacccggaggccgtggtgcgggtcgcgcgcctc
gccttcgagtaccggcagacgttcaacaaggatgtcgtgatcgacctcatctgctaccgc
cgccgcggtcacaacgagggcgacaacccggagttcaccaacccgcagatgtacaccctg
atcgacaagaagcgctcggtgcgcaagctctacaccgagtccctcatcggtcgcggcgac
atcacgctggaagaggccgagcaggcgctccaggacttccagggccagctggagaaggtc
ttcgcggaggtccgcgaggccacctcggcgccgtcccagccgcatgtcccggacgtgcag
gccgagttccccgtcgccgtgaacaccgcggtgtcctcggaggtcgtcaagctgatcgcc
gagtcccaggtgaacatccccgacacggtgaccgtgcacccgcgtctgctgccgcagatg
cagcgccgcgcctcctcggtggagaacggcacgatcgactggggcatgggcgagaccctg
gccatcggttcgctgctgatggagggcaccccggtccggctcgccggccaggacacccgc
cgcggcacgttcgggcagcgtcacgccgtgctcgtcgaccagaagaccggcgaggactac
accccgctgctctacctctccgaggaccaggcccgttacaacgtctacgactcgctgctc
agcgagtacgcggcgatgggcttcgagtacggctactcgctggcccgcccggagtcgctg
gtgatctgggaggcccagttcggtgacttcgtcaacggcgcccagaccgtcgtggacgag
ttcatctcctcggccgagcagaagtggggccagacgtccggcgtcaccctgctgctgccg
cacggctacgagggccaggggccggaccactcgtccgcccgcccggagcgtttcctgcag
atgtgcgcgcaggacaacatgacggtcgcgatgcccaccctgccgtcgaactacttccac
ctcctgcggtggcaggtgcacaacccgcaccacaagccgctgatcgtcttcacgccgaag
tcgatgctgcgcctcaaggccgcggcgtcgaaggtggaggagttcaccacgggcgggttc
cgtccggtcatcggcgacgactcggtcgaggcggaagccgtccgcaaggtcgtcttctgc
gccggcaagctcttctacgacctggacgccgagcgtgtgaagcgcggcgacacggagacg
gcgatcatccgtctggagcgcctgtacccgctgccgggtgcggagatccaggccgagatc
gccaagtacccgaacgcggagaagtacctctgggcccaggaggagccggccaaccagggt
gcgtggccgttcatcgcgctcaacctgatcgaccacctggacctggccgtgggtgccgac
gtgccgcacggcgagcgtctgcgccgcatctcgcgtccgcacgggtcgtccccggcggtc
ggctcggccaagcgccaccaggccgagcagacccagctgatcgacgaggtcttcgaggcc
tga
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