Saccharothrix syringae: EKG83_19560
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Entry
EKG83_19560 CDS
T06258
Name
(GenBank) thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
ssyi
Saccharothrix syringae
Pathway
ssyi00280
Valine, leucine and isoleucine degradation
ssyi00640
Propanoate metabolism
ssyi00785
Lipoic acid metabolism
ssyi01100
Metabolic pathways
ssyi01110
Biosynthesis of secondary metabolites
ssyi01210
2-Oxocarboxylic acid metabolism
Module
ssyi_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ssyi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
EKG83_19560
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
EKG83_19560
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EKG83_19560
Enzymes [BR:
ssyi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
EKG83_19560
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Motif
Pfam:
E1_dh
DXP_synthase_N
Transketolase_N
TPP_enzyme_C
DUF4660
Motif
Other DBs
NCBI-ProteinID:
QFZ19340
UniProt:
A0A5Q0H0Q0
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Position
4525077..4526150
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AA seq
357 aa
AA seq
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MARTRVPERTLLPGEEPLSLLREDGTPVDDAPLAMPDDDVLVELHRRMVIGRRFDTQATA
LTRQGRLAVYPSSRGQEACEVGAVLALREQDWLFPTYRDSVALVTRGVDPAGTLTLLQGG
WHLGYDPYEHRVGPQCTPLATNTLHAVGFAHAARLKGEDTAALVFVGDGATSEGDTHEAL
NFAGVWRAPVVFLVQNNGYAISVPMSKQNAAPSLAHKGIGYGVPSVLVDGNDVAAVYAVV
REALHAGGPTLIEARTYRIEAHTNADDASRYRDAAEVAAWLDRDPVDRIETYLTSRGLLD
QARREAVAAEAERFAAWTRAQLNTDVVPDPDELFEHVYATRPAHLRAQAASLREELA
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
atggcccgcacccgcgtgcccgagcggacgttgctgcccggcgaggaaccgctctcgctg
ctgcgcgaggacggcacaccggtcgacgacgcgcccctggcgatgcccgacgacgacgtg
ctcgtcgagctgcaccggcgcatggtcatcggccgccgcttcgacacccaggccaccgcg
ctgaccaggcagggcaggctggccgtctacccgtcgtcgcgcggccaggaggcgtgcgag
gtcggcgcggtgctggcgctgcgcgagcaggactggctgttccccacctaccgcgactcg
gtcgccctggtcaccaggggtgtggacccggccgggacgctcaccctgctccagggcggc
tggcacctcggctacgacccgtacgagcaccgcgtcggcccgcagtgcaccccgctggcc
accaacaccctgcacgcggtcggcttcgcgcacgcggcccggctcaagggcgaggacacc
gccgcgctggtgttcgtcggcgacggcgccacctccgagggcgacacgcacgaggcgctg
aacttcgcgggcgtgtggcgggcaccggtggtgttcctggtgcagaacaacggctacgcg
atcagcgtgccgatgtccaagcagaacgccgcgccgtcgctggcccacaagggcatcggg
tacggcgtgccgtccgtgctggtggacggcaacgacgtggccgccgtgtacgcggtggtg
cgcgaggccctgcacgccggcggcccgacgctgatcgaggcccgcacctaccggatcgag
gcgcacaccaacgccgacgacgcgtcccgctaccgggacgccgccgaggtcgccgcctgg
ctcgaccgcgacccggtcgaccggatcgagacctacctgacctcgcgcggcctgctcgac
caggcgcgccgcgaggcggtggccgccgaggccgagcggttcgccgcgtggacgcgggcg
cagctgaacaccgacgtcgtgcccgaccccgacgagctgttcgagcacgtctacgcgacc
cggcccgcgcacctgcgggcccaggccgcctcgctgcgggaggaactggcgtga
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