Spirochaeta thermophila DSM 6192: STHERM_c19620
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Entry
STHERM_c19620 CDS
T01315
Name
(GenBank) pyruvate dehydrogenase E1 component, subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
sta
Spirochaeta thermophila DSM 6192
Pathway
sta00010
Glycolysis / Gluconeogenesis
sta00020
Citrate cycle (TCA cycle)
sta00620
Pyruvate metabolism
sta00785
Lipoic acid metabolism
sta01100
Metabolic pathways
sta01110
Biosynthesis of secondary metabolites
sta01120
Microbial metabolism in diverse environments
sta01200
Carbon metabolism
sta01210
2-Oxocarboxylic acid metabolism
Module
sta_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sta00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
STHERM_c19620
00020 Citrate cycle (TCA cycle)
STHERM_c19620
00620 Pyruvate metabolism
STHERM_c19620
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
STHERM_c19620
Enzymes [BR:
sta01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
STHERM_c19620
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
ADN02897
UniProt:
E0RQC1
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Position
complement(2154300..2155316)
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AA seq
338 aa
AA seq
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MGVKRPRTQRGERSDRDLYMKFLREMLLIRLFEEKAAQMYGLRKIGGFCHLYIGQEAVAV
GSIAAIDLSKDYVVTAYRDHGHALACGMDPKVVMAELFGKVTGCSRGKGGSMHMFDVEKH
FLGGNGIVGAQIPVGTGVAFAQKYQGTGGVTLVYFGDGAIHQGAFHEALNMAKIWELPVV
YVCENNQWGMGTFWKKVSAVADLYKLGAAYDIPGVQVDGMDVRAVYEATGEAVSRAREGQ
PVLIEARTYRYKGHSMSDPAKYRTREELEEYKRQDPIGRLKTFMEEEGLLDEETFRSLYD
EIQREVEEAVAFAEQSEEPALHTMYEDVYAGEDAIWRS
NT seq
1017 nt
NT seq
+upstream
nt +downstream
nt
atgggagtgaaacgccctcgcacacagagaggggagaggtccgaccgggatctctacatg
aagttcctgagggagatgctcctcatccgcctcttcgaggagaaggcggcccagatgtac
gggctcaggaagatcggggggttctgccacctctacatcgggcaggaggcggtggccgtg
ggttccatcgccgcgatcgatctttcgaaggactacgtggtcacggcctaccgggatcac
ggccatgccctcgcctgcggcatggatccgaaggtggtgatggccgagctcttcgggaag
gtgacggggtgtagcagggggaagggagggtccatgcacatgttcgacgtggagaagcac
ttcctcggcggcaacgggatcgtgggtgcccagatcccggtggggaccggggtggcgttc
gcgcagaagtaccagggcacggggggggtgacgctcgtgtacttcggggacggcgccatc
caccagggggccttccacgaggcgctcaacatggcgaagatctgggagctgccggtggtc
tacgtctgcgagaacaaccagtggggtatggggaccttctggaagaaggtctcggccgtg
gccgacctctacaagctcggtgcggcgtacgacatccccggcgtccaggtggatgggatg
gacgtgcgggcggtgtacgaggccacgggcgaggcggtctcccgcgcgagggaggggcaa
ccggtgctcatcgaggcccggacctaccggtacaagggccactccatgagcgatcctgcg
aagtatcgtacgagggaggagctcgaggagtacaagcgtcaggatcccatcggcaggctc
aagaccttcatggaggaggaggggctcctcgacgaggagaccttccgcagcctctacgac
gagatccagagggaggtggaggaggcggtggcgttcgcggagcagagcgaggagcctgcc
ctccacaccatgtacgaagacgtatacgcaggggaggatgcgatatggcggtcatga
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