Streptococcus pyogenes MGAS15252 (serotype M59): MGAS15252_0778
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Entry
MGAS15252_0778 CDS
T01794
Symbol
acoA
Name
(GenBank) acetoin dehydrogenase E1 component alpha-subunit AcoA
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
stg
Streptococcus pyogenes MGAS15252 (serotype M59)
Pathway
stg00010
Glycolysis / Gluconeogenesis
stg00020
Citrate cycle (TCA cycle)
stg00620
Pyruvate metabolism
stg00785
Lipoic acid metabolism
stg01100
Metabolic pathways
stg01110
Biosynthesis of secondary metabolites
stg01120
Microbial metabolism in diverse environments
stg01200
Carbon metabolism
stg01210
2-Oxocarboxylic acid metabolism
Module
stg_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
stg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MGAS15252_0778 (acoA)
00020 Citrate cycle (TCA cycle)
MGAS15252_0778 (acoA)
00620 Pyruvate metabolism
MGAS15252_0778 (acoA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MGAS15252_0778 (acoA)
Enzymes [BR:
stg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MGAS15252_0778 (acoA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AFC66124
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Position
758091..759059
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AA seq
322 aa
AA seq
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MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVGEEAANVGAVAHLSYDD
IIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMHLADFEKGNYGTNGIVGGG
YALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNMAATWKLPVIFFIINNRYGIS
MSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYETMGKAVEHVRGGNGPAIVEVESY
RWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLTSEGIATDDELDAIQAQVKKEVDDA
YEFAQNSPDPELSVAFEDVWVD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atggtaacagtttctaaagaacaacatttggatatgttccttaaaatggaacgtattcgt
gaatttgattcacgtattaataaactcgtccgtcgtggatttgtacaagggatgactcac
ttctcagttggtgaagaagcagccaatgttggagcggtggctcacttgtcttacgatgac
attattttttcaaatcaccgtggacatggacaatcaatcgctaaagacatggaccttaat
aaaatgatggctgagcttgctggtaaagcaactggtgtgtctaaagggcgtggtggctca
atgcacttggctgattttgaaaaaggaaactatggtaccaatggtatcgttggtggtggt
tacgctcttgcagttggtgctgccctcactcaacaatacaaaggaactaacaatatagct
gttgctttctcaggtgatggcgctactaacgaaggatcattccacgagtctgttaatatg
gctgcaacatggaaacttcctgttattttcttcatcatcaacaaccgttatggaatttca
atgagcatcaataatgcaacaaatacaccacacttatacacacgtgcagaagcttacgga
attcctggtttctactgtgaagatggcaatgacgtgatggctgtctatgaaacaatgggc
aaagccgttgaacatgttcgtggtggaaatggtccagctattgttgaggtagaatcatac
cgttggtttggtcactcgactgcagatgctggtaaataccgtactaaagaagaagtggat
gagtggaaagaaaaagatccaatgatcaaatatcgtacttatctgacaagcgaaggcatt
gccactgatgacgaattggatgctattcaagcacaagtcaaaaaagaagttgacgatgct
tatgaatttgcacaaaacagtccagatccagaactttcagtagccttcgaagacgtttgg
gttgactaa
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