Sphaerobacter thermophilus: Sthe_3030
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Entry
Sthe_3030 CDS
T01128
Name
(GenBank) FolC bifunctional protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sti
Sphaerobacter thermophilus
Pathway
sti00790
Folate biosynthesis
sti01100
Metabolic pathways
sti01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sti00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Sthe_3030
Enzymes [BR:
sti01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Sthe_3030
6.3.2.17 tetrahydrofolate synthase
Sthe_3030
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
DUF3670
Motif
Other DBs
NCBI-ProteinID:
ACZ40432
UniProt:
D1C9D9
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All DBs
Position
2:678113..679471
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AA seq
452 aa
AA seq
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MDYREAIAYIIERSGYDRGFVANPFDAETVGLQRTKWLLEALGNPEERFTAVHIAGTKGK
GSTGACVAAILRAAGKRTGLYSSPHLHTFRERVQIDGEPITPEDFAALTAELAAVNSRLA
EARPDWGEATAFEVSTALAFLAFARAGVEVGVVEVGLGGRLDATNVVTPAVAVITPISYD
HTAILGDTLDAIATEKGGIIKPGRPVVLGPQPPEALATLERIAAERGSPVYRAGRDWHAT
GTDTGFDLTGPWGTIRDLRVALRGRHQVENAATAVAACWLLREQGIDIPEDAIRAGLAAV
HWPGRLEVVREQPLVVVDGAHNVDAAARLAEALVDTFGQRRRTLVLGIARDKDIPAMLEI
LAPLADRIIATASHHPRAADPAQVAAAARAAGGAGLAVEEAPDIATGLHRALDAAAPEDL
ICVTGSLYAVSEAREALGLAQADDFERELLFR
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggactaccgggaggcgatcgcctacatcatcgagcgctccggctacgaccggggcttc
gtagccaaccccttcgacgccgagacggtcggcctccaacgcaccaagtggttactggaa
gcgctcggcaaccccgaggagcgcttcaccgccgtgcacatcgcaggcaccaaggggaag
ggctcgaccggggcctgcgtcgccgccatcctgcgcgccgcgggaaaacgcaccggcctc
tactcctcaccccacctccacaccttccgcgagcgggtccagatcgacggcgagccgatc
acgcctgaggacttcgccgccctgaccgccgagcttgccgcggtcaacagccgcctggcc
gaggcgcggcccgactggggcgaggccaccgccttcgaggtctccaccgcgctcgccttc
ctcgccttcgctcgggctggtgttgaggtcggcgtggtcgaggtcggactcggcgggcga
ctcgacgccaccaacgtcgtcaccccggccgtcgccgtcatcaccccgatcagctacgac
cacaccgccatcctgggcgacaccctcgacgcgatcgcgaccgagaaggggggcatcatc
aagccgggccgcccggtcgtcctcggcccacagccgcccgaagccctggccaccctggag
cggatcgccgccgagcgcggcagcccggtctaccgggccggtcgcgactggcatgcgacc
ggcaccgacaccggcttcgacctgaccggcccgtgggggaccatccgcgacctgcgcgtc
gcgctgcgcgggcgacaccaggtggagaacgcagccacggccgtcgccgcctgctggcta
ctgcgcgagcagggcatcgacatcccggaggacgccatccgcgccgggctggcagcggtc
cactggcccggccgcctggaagtcgtgcgtgagcagcccctggtcgtggtcgacggcgcg
cacaacgtcgacgccgccgcccgcctcgccgaggcgctggtcgacaccttcggacagcgc
cgccgcacgctcgtcctcggcattgcccgggacaaagacatcccggcgatgctggagatc
ctcgccccgctggcggaccggatcatcgccactgcctcccaccacccccgggccgccgat
ccggcccaggtcgcagccgccgcccgggcggccggcggcgccgggctcgccgtcgaggag
gctcccgacatcgccaccgggctacaccgcgcactggatgccgccgcgccggaagacctg
atctgcgtcaccggctccctctacgccgtttccgaggcccgcgaggccctcggcctcgcc
caggccgacgacttcgagcgcgagctgctgttccggtga
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