Salmonella enterica subsp. enterica serovar Typhimurium LT2: STM0112
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Entry
STM0112 CDS
T00065
Symbol
leuB
Name
(RefSeq) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
stm
Salmonella enterica subsp. enterica serovar Typhimurium LT2
Pathway
stm00290
Valine, leucine and isoleucine biosynthesis
stm00660
C5-Branched dibasic acid metabolism
stm01100
Metabolic pathways
stm01110
Biosynthesis of secondary metabolites
stm01210
2-Oxocarboxylic acid metabolism
stm01230
Biosynthesis of amino acids
Module
stm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
stm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
STM0112 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
STM0112 (leuB)
Enzymes [BR:
stm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
STM0112 (leuB)
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Gene cluster
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
1251630
NCBI-ProteinID:
NP_459117
UniProt:
P37412
Structure
PDB
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All DBs
Position
complement(131076..132167)
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AA seq
363 aa
AA seq
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MSKNYHIAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKA
TVEGCEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAF
CPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAF
ESARKRRRKVTSIDKANVLQSSILWREIVNDVAKTYPDVELAHMYIDNATMQLIKDPSQF
DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIA
QILSLALLLRYSLDANDAATAIEQAINRALEEGVRTGDLARGAAAVSTDEMGDIIARYVA
EGV
NT seq
1092 nt
NT seq
+upstream
nt +downstream
nt
atgtcgaagaactatcatattgccgtactgccgggcgacggtatcggcccggaagtcatg
gcgcaagccctgaaagttatggatgcggtacgcagccgttttgatatgcgtataaccacc
agccactatgacgtcggcggtattgctatcgacaatcatggtcatccactgccgaaagcc
accgttgaagggtgcgagcaggcggatgccattctgtttggctccgtcggcggcccgaaa
tgggaaaatttgcccccggaaagccagccggagcgcggcgccctgctgccgctgcgcaaa
catttcaaattattcagtaacctgcgtccggcgaaactgtatcagggactggaagcattt
tgcccgttgcgcgccgatatcgccgctaacggtttcgatatcctgtgcgtgcgcgagctg
accggcgggatctatttcggacagccaaaaggccgtgaaggcagcggtcagtacgaaaaa
gcctttgataccgaagtttatcaccgctttgagatcgagcgcattgcccgtatcgccttt
gaatcggcgcgtaaacgccgccgtaaagtcacctctattgataaagccaacgtactgcaa
agctctatcctgtggcgtgaaatcgtcaatgatgtcgcgaaaacgtatcccgatgtggaa
ctcgcgcacatgtatatcgataacgccaccatgcagttgattaaagacccgtcgcagttt
gacgtactgctgtgctctaacctgttcggcgacattctgtccgacgaatgcgccatgatc
accggctcaatggggatgttgccctccgccagcctgaacgagcaagggtttggcctgtat
gaaccggctggcggctccgcgccggatatcgccgggaaaaatatcgccaacccaattgcg
cagatcctgtcactggcgctgctgctgcgctacagcctggatgccaacgatgcggcaacg
gccattgaacaggcgatcaatcgcgcattagaagagggcgttcgcaccggcgatttagcc
aggggcgctgccgcagtcagtaccgatgagatgggcgatattatcgcccgctatgtcgca
gaaggggtgtaa
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