Spirochaeta thermophila DSM 6578: Spith_2010
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Entry
Spith_2010 CDS
T02016
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
stq
Spirochaeta thermophila DSM 6578
Pathway
stq00010
Glycolysis / Gluconeogenesis
stq00020
Citrate cycle (TCA cycle)
stq00620
Pyruvate metabolism
stq00785
Lipoic acid metabolism
stq01100
Metabolic pathways
stq01110
Biosynthesis of secondary metabolites
stq01120
Microbial metabolism in diverse environments
stq01200
Carbon metabolism
stq01210
2-Oxocarboxylic acid metabolism
Module
stq_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
stq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Spith_2010
00020 Citrate cycle (TCA cycle)
Spith_2010
00620 Pyruvate metabolism
Spith_2010
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Spith_2010
Enzymes [BR:
stq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Spith_2010
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
AEJ62268
UniProt:
G0GED1
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Position
complement(2249208..2250230)
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AA seq
340 aa
AA seq
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MGVKRPGTQKGGKEKQRRDLYMKFLREMLLIRVFEEKSAQMYGLRKIGGFCHLYIGQEAV
AVGSIAAIDLAKDYVVTAYRDHGHALACGMDPKVVMAELFGKVTGCSRGKGGSMHMFDVE
KHFLGGNGIVGAQIPVGTGVAFAQKYEGTGGVTLVYFGDGAIHQGAFHEALNLAKIWELP
VVYICENNQWGMGTFWKKVSAVADLYKLGAAYDIPGVQVDGMDVRAVYEATTEAVSRARE
GDPVLIEARTYRYKGHSMSDPAKYRTREELEEYKRQDPIGRLKTFMEEEGLLEEKTFRAL
YEEIQKEVDEAVEFAERSEEPALHTIYEDVYAGEDATWRS
NT seq
1023 nt
NT seq
+upstream
nt +downstream
nt
atgggagtgaaacgcccgggtacacagaagggagggaaggaaaagcagcgccgggacctc
tacatgaagttcctgagggagatgctcctcatccgcgtcttcgaggagaagtcggcccag
atgtacgggctcaggaagatcggggggttctgccacctctacatcgggcaggaggcggtg
gccgtgggctccatcgccgcgatcgatcttgcgaaggactacgtggtcacggcctaccga
gatcacggccatgctctcgcctgcggcatggatccgaaggtggtgatggccgagctcttc
gggaaggtgacggggtgcagtagggggaaaggcggatccatgcacatgttcgacgtggag
aagcacttcctcgggggtaacgggatcgtgggtgcccagatcccggtggggaccggggtg
gcgttcgcccagaagtacgaggggaccggaggagtgacgctcgtgtatttcggagacggc
gccatccaccagggggccttccacgaggcactcaacctggccaagatctgggagctcccg
gtggtctatatctgtgagaacaaccagtgggggatggggaccttctggaagaaggtctcg
gctgtggccgatctctacaagctcggggcggcctacgacatccccggtgtgcaggtggac
gggatggacgtgcgggcggtctacgaggccaccactgaggcggtctcccgcgcgagggag
ggagacccggtgctcatcgaggcccgcacctaccgttacaaggggcattccatgagcgac
cctgcaaaataccgtacgagggaggagctcgaggagtacaagcgccaggatcccataggg
aggctcaagactttcatggaggaggaggggcttctcgaagagaagacgttcagggccctc
tatgaggagattcaaaaggaagtggatgaggctgtggagtttgccgagcgaagtgaagag
cctgcacttcacaccatatacgaagatgtgtatgcaggggaggatgccacatggcggtca
tga
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