Streptomyces qaidamensis: A4E84_12375
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Entry
A4E84_12375 CDS
T04777
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
stsi
Streptomyces qaidamensis
Pathway
stsi00010
Glycolysis / Gluconeogenesis
stsi00020
Citrate cycle (TCA cycle)
stsi00620
Pyruvate metabolism
stsi00785
Lipoic acid metabolism
stsi01100
Metabolic pathways
stsi01110
Biosynthesis of secondary metabolites
stsi01120
Microbial metabolism in diverse environments
stsi01200
Carbon metabolism
stsi01210
2-Oxocarboxylic acid metabolism
Module
stsi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
stsi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
A4E84_12375
00020 Citrate cycle (TCA cycle)
A4E84_12375
00620 Pyruvate metabolism
A4E84_12375
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
A4E84_12375
Enzymes [BR:
stsi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
A4E84_12375
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
RL
Motif
Other DBs
NCBI-ProteinID:
AMW10237
UniProt:
A0A143BYF1
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All DBs
Position
2824182..2826929
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AA seq
915 aa
AA seq
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MASASDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIPTKSEPFFPGNEDIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQVFFQGHASPGIYARAFLLDRLNEQHLDGFRQ
EKSKAPHALSSYPHPRSMPDFWEFPTVSMGLGPIGAIYQARMNRYMAARGIADTSKSQVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESIFRGA
GWNVIKLVWDRSWDPLLAQDRDGVLVNKMNTTPDGQFQTYATETGAYIRDHFFGDDHRLR
AMVEGMTDDQILHLGRGGHDHKKIFAAYKAAAEHKGQPTVILAKTIKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHLPIPDKELESGVPPYYHPGRDSEEIQYMHDRRKSLGGYVP
TRVVRSKPLALPEDKTYATVKKGSGQQSIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRDLLLAYKEAPNGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAFGFEIAHIVKDGLRRMYGSSEEHPHGEDVFYYLTVYNEPIQH
PAEPENVDVDGILKGLYRFSEGTAGEIPAQVLASGVALPWAVEAQKILAEDWNVKADVWS
ATSWNELRREAVSCEEHNLLHPEEEQRVPYVTRKLADAQGPVVAVSDWMRAVPDQIARWV
PQTYQSLGADGFGFADTRGAARRFFHIDAQSIVVGVLTELAREGKVDRSVLKQAIDRYQL
LDVSAADPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccgcatccgatcgcaacccgatcatcattggcggccttccgagtcaggttcct
gacttcgatcccgaagagacgcaggagtggctcgactcgctcgacgccgccgtcgacgag
cggggccgggagcgggcccgctacctgatgctgcggctgatcgagcgggcccgcgagaag
cgcgtggccgtgccggagatgcgcagcacggactacgtcaacaccatccccaccaagagc
gagccgttcttcccgggcaacgaggacatcgagcgcaaggtcctcaacgccacccgctgg
aacgcggcggtgatggtctcccgggcccagcgccccggcatcggcgtcggcgggcacatc
gccacgttcgcgtcctccgcctccctctacgacgtcggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccaggtcttcttccaggggcacgcctcaccgggcatc
tacgcccgcgcgttcctgctcgaccggctgaacgagcagcacctggacggcttccgccag
gagaagtcgaaggcgccgcacgcgctgtcgtcgtacccgcacccgcggtcgatgccggac
ttctgggagttcccgacggtgtcgatgggcctcggcccgatcggtgcgatctaccaggcg
cggatgaaccgttacatggcggcgcgcgggatcgccgacacctcgaagtcgcaggtgtgg
gctttcctcggcgacggcgagatggacgagccggagtcgctgggccagctgtccatcgcc
gcccgcgagggcctggacaacctcacgttcgtcgtgaactgcaacctccagcgcctcgac
ggcccggtgcgcggcaacgggaagatcatccaggagctggagtcgatcttccgcggcgcc
ggctggaacgtgatcaagctggtctgggaccgcagctgggacccgctgctcgcccaggac
cgcgacggcgtgctggtcaacaagatgaacaccacgccggacgggcagttccagacgtac
gccacggagaccggcgcgtacatccgcgaccacttcttcggtgacgaccaccggctgcgg
gccatggtcgagggcatgaccgacgaccagatcctgcacctgggccgcggcggtcacgac
cacaagaagatcttcgcggcgtacaaggcggccgcggagcacaagggccagccgacggtg
atcctcgccaagacgatcaagggctggacgctgggcccgaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgacgacctcaagcgcttccgcgaccgtctgcac
ctgccgatcccggacaaggagctggagtccggcgtgccgccgtactaccacccgggccgg
gactcggaggagatccagtacatgcacgaccgccgcaagtcgctcggcggttacgtcccc
acgcgcgtggtgcgctccaagccgctggcgctgcccgaggacaagacgtacgcgaccgtg
aagaagggctcgggccagcagtccatcgcgacgacgatggctttcgtccgactcctgaag
gacctcatgcgggacaaggagatcggcaagcgtttcgtgctgatcgcgcctgacgagtac
cgcaccttcggcatggactcgttcttcccgagtgcgaagatctacaacccgctaggccag
cagtacgagtcggtcgaccgcgacctgctcctcgcctacaaggaggcgccgaacggccag
atgctgcacgacggcatctccgaggcgggctgcacggcgtccctgatcgccgccggatcg
gcctacgcgacccacggcgagccgctcatcccggtctacgtcttctactcgatgttcggt
ttccagcgcaccggcgaccagttctggcagatggccgaccagctggcgcgcggcttcgtc
ctgggcgcgaccgccggccgtacgaccctgaccggtgagggcctgcagcacgcggacggc
cactcccagctgctggcctcgacgaacccgggctgcgtcgcctacgacccggcgttcggc
ttcgagatcgcccacatcgtcaaggacggcctgcgccggatgtacggctcctccgaggag
catccgcacggcgaggacgtcttctactacctgaccgtctacaacgagcccatccagcac
ccggccgagcccgagaacgtggacgtcgacggcatcctcaagggcctctaccggttcagc
gagggcacggccggtgagatcccggcgcaggtcctggcgtccggtgtcgcgctgccctgg
gccgtcgaggcgcagaagatcctggccgaggactggaacgtcaaggcggacgtctggtcg
gcgacctcctggaacgagctgcggcgcgaggccgtgagctgcgaggagcacaacctgctg
caccccgaggaggagcagcgggtgccgtacgtgacgcgcaagctcgccgacgcgcagggg
ccggtcgtggccgtgtccgactggatgcgggcggttccggaccagatcgcgcgctgggtg
ccgcagacgtaccagtcgctgggagcggacggcttcggcttcgccgacacgcggggcgcc
gcccggcggttcttccacatcgacgcgcagtcgatcgtggtgggcgtgctgaccgagctg
gcccgtgagggcaaggtcgaccgctccgtgctcaagcaggccatcgaccgctaccagctg
ctcgacgtgtcggccgccgacccgggagccgcgggcggcgacgcgtag
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