Streptomyces tsukubensis: B7R87_09365
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Entry
B7R87_09365 CDS
T07155
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
stsu
Streptomyces tsukubensis
Pathway
stsu00790
Folate biosynthesis
stsu01100
Metabolic pathways
stsu01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
stsu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
B7R87_09365
Enzymes [BR:
stsu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
B7R87_09365
6.3.2.17 tetrahydrofolate synthase
B7R87_09365
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AZK94060
UniProt:
A0A5H2UHX3
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Position
complement(2445545..2447086)
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AA seq
513 aa
AA seq
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MSEHPADPQPNDPRAHEPEPYERDVFDEIVDTETDRDPDLAVIEAGSRTLRAQAGPPDAQ
VPEPPADPEVAAALRAVEAELASRWGETKLEPSVRRIAALMDVLGEPQRAYPSIHITGTN
GKTSTARMVEALLAAFDLRTGRYTSPHVRSVTERISLDGSPVSAERFVSVYEDVKPYVEM
VDAAEDYRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGTWDATNVIDASVAVVTPIDLD
HTDRLGSTPGEIAAEKSGIVKQGATVVLAQQPVDAAQVLLKKAVEVDATVAREGMEFGIV
SREVAVGGQLLTLRGLGGEYPEVFLPLYGAHQAHNAVVALAAVEAFFGVGADHARVLDID
TVRRAFASVSSPARLEVVRRSPTVVLDAAHNPAGARATAEAITEAFGFSRLIGVVGTSAG
KDVRGLLEAFEPVFAEIVVTRNSTERSMDPDELAAIAVEVFGEERVVVEPQLDEALEAAV
TLAEEDAEYAGAGVLVTGSVFTAGEARLLLGKG
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagcaccccgccgacccccagccgaacgatccccgggcgcacgagccggagccg
tacgagcgtgacgtcttcgacgagatcgtcgacacggagaccgaccgcgatcccgacctc
gcggtgatcgaggcgggcagccgcacgctgcgcgcccaggccggtccgccggacgcccag
gtgccggagccgcccgcggacccggaggtcgccgccgcgctgcgcgccgtggaggccgag
ctggcctcgcgctggggcgagacgaagctggagccctcggtgcggcggatcgcggcactg
atggacgtgctgggcgagccccagcgggcgtacccctccatccacatcaccggcaccaac
ggcaagacgtccacggcccggatggtcgaggcgctcctcgccgcgttcgatctgcgcacc
ggccgctacacctcgccgcatgtgcggtccgtcaccgagcggatcagcctggacggctcg
ccggtgagcgcggagcggttcgtctccgtgtacgaggacgtcaagccgtacgtggagatg
gtggacgccgcggaggactaccgtctgtcgttcttcgaggtgctgaccggtatggcgtac
gcggcgttcgcggacgccccggtggacgtggccgtcgtcgaggtcggcatgggcgggacc
tgggacgcgaccaatgtcatcgacgcttcggtggccgtggtgacgcccatcgacctggac
cacaccgaccggctgggcagcacgcccggcgagatcgccgccgagaagtcggggatcgtc
aagcagggggcgacggtcgtcctggcccagcagccggtggacgcggcgcaggtgctgctg
aagaaggccgtcgaggtggatgcgacggtggcccgcgagggcatggagttcgggatcgtg
tcccgggaggtcgcggtcggcggccagctgctgaccctgcgcgggctcggcggcgagtac
cccgaggtcttccttccgctctacggggcccaccaggcgcacaacgcggtggtggcgctc
gccgcggtcgaggccttcttcggggtgggcgcggaccacgcccgggtgctggacatcgac
acggtccgccgggccttcgcctcggtctccagcccggcgcggctggaagtggtgcggcgc
agtccgaccgtggtgctggacgcggcgcacaatccggcgggtgcccgggcgacggcggag
gcgatcacggaggccttcggcttctcccggctgatcggtgtcgtcgggaccagcgcgggc
aaggacgtccgcggtctgctggaggcgttcgagccggtgttcgcggagatcgtggtcacc
cggaactccaccgagcggagcatggaccccgacgagctggcggcgatcgccgtggaggtc
ttcggggaggagcgtgtggtggtggagccgcagctggacgaggccctggaggcggcggtg
accctcgccgaggaggacgccgagtacgcgggcgccggagtgctggtgacgggttcggtg
ttcacggccggggaagcccggctgctgctggggaagggctga
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