Streptomyces tubercidicus: STRTU_004738
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Entry
STRTU_004738 CDS
T09099
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
stud
Streptomyces tubercidicus
Pathway
stud00790
Folate biosynthesis
stud01100
Metabolic pathways
stud01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
stud00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
STRTU_004738
Enzymes [BR:
stud01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
STRTU_004738
6.3.2.17 tetrahydrofolate synthase
STRTU_004738
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
WAU14153
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Position
5458643..5460196
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AA seq
517 aa
AA seq
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MSERPQNDDPDPTDAFDELVEAETDLPQDLDSARSGETPIPDLAVIEAGSRTLRAQAGPP
QGDGIPARPADPEVDRALRAVEEELAGRWGETKLDPSVQRIAALLDILGEPQRAYPSIHI
TGTNGKTSTARMIEALLSAFDLRTGRYTSPHVQSITERISLDAAPISAERFIETYRDIAP
YVEMVDAQQEYRLSFFEVLTAMAYAAFADSPVDVAVVEVGMGGTWDATNVIDGDVAVITP
ISLDHTDRLGETPEQIAGEKSGIIKKDATVVLAQQPVDAASVMLKRAVEVDATVAREGME
FGVLSREVAVGGQMLTLRGLGGEYPEIFLPLYGAHQAHNAAVALAAVEAFFGVGSEQART
LDIDTLRSAFAAVTSPGRMEVVRRSPTVVLDAAHNPAGARAAAEAVTEAFGFSRLVGVVG
ASDDKDVRGLLEAFEPIFAEIVVTRNSSHRAMDPDELAAVAVEVFGAERVQVEPRLDDAL
EAAITLAEEEGEFSGAGVLVTGSVITVGEARLLMGRG
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgagcgcccccagaacgacgaccccgacccgaccgacgccttcgacgaactggtc
gaggccgagaccgaccttccccaagatctcgactccgctcgatcaggggagaccccaatc
cccgatctggccgtgatcgaggccggcagccgcaccctgcgtgcccaggccggtccgccg
cagggggacgggatccccgcccgcccggccgaccccgaggtcgaccgtgcgctgcgcgcc
gtggaggaggagctggcgggccgctggggcgagaccaagctggacccgtcggtgcagcgc
atcgcggcgctgctggacatcctcggcgagccgcagcgcgcctacccgtccatccacatc
accggcaccaacggcaagaccagcaccgcccgcatgatcgaggccctgctgtccgccttc
gacctgcgcaccggccgctatacgagcccgcatgtccagtcgatcaccgagcggatcagc
ctggacgccgccccgatctccgccgagcgcttcatcgagacctaccgggacatcgccccg
tatgtggagatggtcgacgcccagcaggagtaccgcctgtcgttcttcgaggtgctgacg
gcgatggcctacgccgccttcgcggacagccccgtggacgtcgcggtcgtcgaggtcggc
atgggcggcacctgggacgcgacgaacgtcatcgacggcgatgtcgccgtgatcaccccg
atctcgctggaccacaccgaccggctgggggagacgcccgagcagatcgccggtgagaag
tccgggatcatcaagaaggacgccacggtcgtgctggcccagcagccggtggacgcggcg
tcggtgatgctcaagcgcgcggtcgaggtggatgccacggtcgcccgtgagggcatggag
ttcggggtgctctcccgtgaggtggccgtcggcgggcagatgctgacgctgcgcggactg
ggcggcgagtatccggagatcttcctgccgctgtacggcgcccaccaggcgcacaacgcc
gcggtggcgctcgccgcggtcgaggcgttcttcggcgtcggctcggagcaggccaggacg
ctggacatcgacaccctccgctccgcgttcgccgccgtcacctcacccggccggatggag
gtcgtgcgccgcagccccacggtggtgctggacgcggcccacaacccggcgggggcgcgg
gcggcggccgaggcggtcaccgaggcgttcgggttcagccggctggtcggtgtggtcggt
gccagtgacgacaaggacgtccggggcctcctggaggccttcgagccgatcttcgcggag
atcgtggtgacgcgtaattccagccatcgtgcgatggacccggatgagctggcggcggtc
gccgtcgaggtcttcggcgccgagcgggtccaggtggagccgcggctcgacgacgccctg
gaggcggcgatcaccctcgccgaggaggagggcgagttctccggtgccggtgtgctggtg
accggctcggtgatcacggtcggcgaggcccggctgctgatgggaaggggctga
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