Streptococcus pyogenes MGAS1882 (serotype M59): MGAS1882_0774
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Entry
MGAS1882_0774 CDS
T02062
Symbol
acoA
Name
(GenBank) acetoin dehydrogenase E1 component alpha-subunit AcoA
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
stx
Streptococcus pyogenes MGAS1882 (serotype M59)
Pathway
stx00010
Glycolysis / Gluconeogenesis
stx00020
Citrate cycle (TCA cycle)
stx00620
Pyruvate metabolism
stx00785
Lipoic acid metabolism
stx01100
Metabolic pathways
stx01110
Biosynthesis of secondary metabolites
stx01120
Microbial metabolism in diverse environments
stx01200
Carbon metabolism
stx01210
2-Oxocarboxylic acid metabolism
Module
stx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
stx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MGAS1882_0774 (acoA)
00020 Citrate cycle (TCA cycle)
MGAS1882_0774 (acoA)
00620 Pyruvate metabolism
MGAS1882_0774 (acoA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MGAS1882_0774 (acoA)
Enzymes [BR:
stx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MGAS1882_0774 (acoA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AFC67988
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Position
755516..756484
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AA seq
322 aa
AA seq
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MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVGEEAANVGAVAHLSYDD
IIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMHLADFEKGNYGTNGIVGGG
YALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNMAATWKLPVIFFIINNRYGIS
MSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYETMGKAVEHVRGGNGPAIVEVESY
RWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLTSEGIATDDELDAIQAQVKKEVDDA
YEFAQNSPDPELSVAFEDVWVD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atggtaacagtttctaaagaacaacatttggatatgttccttaaaatggaacgtattcgt
gaatttgattcacgtattaataaactcgtccgtcgtggatttgtacaagggatgactcac
ttctcagttggtgaagaagcagccaatgttggagcggtggctcacttgtcttacgatgac
attattttttcaaatcaccgtggacatggacaatcaatcgctaaagacatggaccttaat
aaaatgatggctgagcttgctggtaaagcaactggtgtgtctaaagggcgtggtggctca
atgcacttggctgattttgaaaaaggaaactatggtaccaatggtatcgttggtggtggt
tacgctcttgcagttggtgctgccctcactcaacaatacaaaggaactaacaatatagct
gttgctttctcaggtgatggcgctactaacgaaggatcattccacgagtctgttaatatg
gctgcaacatggaaacttcctgttattttcttcatcatcaacaaccgttatggaatttca
atgagcatcaataatgcaacaaatacaccacacttatacacacgtgcagaagcttacgga
attcctggtttctactgtgaagatggcaatgacgtgatggctgtctatgaaacaatgggc
aaagccgttgaacatgttcgtggtggaaatggtccagctattgttgaggtagaatcatac
cgttggtttggtcactcgactgcagatgctggtaaataccgtactaaagaagaagtggat
gagtggaaagaaaaagatccaatgatcaaatatcgtacttatctgacaagcgaaggcatt
gccactgatgacgaattggatgctattcaagcacaagtcaaaaaagaagttgacgatgct
tatgaatttgcacaaaacagtccagatccagaactttcagtagccttcgaagacgtttgg
gttgactaa
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