Subtercola sp. PAMC28395: KPL76_09095
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Entry
KPL76_09095 CDS
T07261
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
subt
Subtercola sp. PAMC28395
Pathway
subt00790
Folate biosynthesis
subt01100
Metabolic pathways
subt01240
Biosynthesis of cofactors
Module
subt_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
subt00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
KPL76_09095
Enzymes [BR:
subt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
KPL76_09095
6.3.2.17 tetrahydrofolate synthase
KPL76_09095
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
RMNT_CmcI
DUF1442
Motif
Other DBs
NCBI-ProteinID:
QWT25363
UniProt:
A0A975SJP5
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Position
1968621..1970054
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AA seq
477 aa
AA seq
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MADAYDTQLVDRQNRADGENGDSDYDDLPDEYVEAGDEVFRQLQLRLGEAAPQPRLSATR
RAVEMLGDPHRAYPVIHITGTNGKTSTSRLTESILRAYGLRTGLFTSPHLERLNERIMID
GRPISNESLAENWADIQPYLELVDAELEGAGEPRLTFFEALSVLAFASFAEAPIDVAVIE
VGMGGEWDSTNVADGQVAVFTPISLDHTARLGNTVAEIARTKSGIVKPAAQVVTSRQVPE
VLAELQRAAELTESTFASEGAAFSLLSTSVAVGGQVISIKGLAGTYRDVFLPLYGDHQAQ
NAAVAVAAVESFLGGGSTAIVEDVLVEAFATVTSPGRLQLIGTEPTVLVDAAHNPGGALA
LAAALKEYFSFDKIVAVISVLADKDAAGIIRALEPVVSEFVVTQSSSERAINADELASIV
VGIAGADRVVVELDPREAANLARDSAAESDTGAVLVTGSITLVGEIITLAGDEGWKP
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atggccgatgcgtacgacacgcagctggtcgatcgccagaatcgtgccgatggcgagaat
ggcgactccgactacgacgacctgcccgacgaatacgtcgaggcgggcgacgaggttttc
cggcagctgcagttgcgcctgggggaggcggccccgcagccacggctctcggcgacacgg
cgcgcggtcgagatgctgggtgacccgcaccgggcctacccggtcatccacatcaccggc
acgaacggcaagacgagcaccagccgcctcactgagagcatcctgcgcgcctacggcctg
cgtaccgggctgttcaccagcccacatctcgaacgcctgaacgagcggatcatgatcgac
ggccggccgatcagcaatgagtcgctcgccgagaactgggccgacatccagccctacctc
gagctggtggatgctgaactcgagggtgccggcgaaccccgcctgacgttcttcgaggcc
ctctctgtgctggccttcgcgtcgttcgccgaagcgccgatcgacgtcgccgtgatcgag
gtcggcatgggcggagagtgggattcgaccaacgttgccgacggccaggtcgcggtcttc
acgccgatctcgctcgaccacaccgccaggctcggcaacaccgtcgccgagatcgcccgc
accaagtcgggcatcgtgaagcccgcggcccaggtcgtcacctcgaggcaggtgccggag
gtgctggcagagcttcagcgtgcggccgagctcaccgaatcgacgttcgcctcagagggc
gcggcgttctccctgctctcgaccagcgtcgccgtcggtggccaggtcatctcgatcaag
gggctcgccggaacgtaccgcgacgtgttcctgcccctgtacggcgaccaccaagcccag
aatgcggcggtcgccgtggcggctgtggagtcgttcctcggcggcgggtcgaccgcgatc
gtcgaagacgtgctcgtcgaggcgttcgccactgtcacctctcccgggcgcctgcagctg
atcggcaccgagccgacggttctggtggatgctgcgcacaaccccggcggagcgctggcg
ctcgcggcggcactgaaggagtacttctccttcgacaagatcgtcgctgtgatcagtgtt
ctcgccgacaaggacgccgccggcatcatccgcgcgctcgagccggtcgtttcggagttc
gtcgtcacgcagtcctcgtcggagcgcgcgatcaacgccgacgagctggcgagtatcgtc
gtcggcatcgccggggcagaccgcgttgtggtcgaactcgacccgcgggaggccgccaat
ctcgccagggactctgcggcagaatccgacaccggtgccgtgctcgtgaccggctcgatc
acgctcgtcggtgagatcatcaccctcgcaggcgacgaggggtggaagccgtga
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