Staphylococcus aureus subsp. aureus TW20 (MRSA): SATW20_10880
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Entry
SATW20_10880 CDS
T02060
Symbol
pdhA
Name
(GenBank) putative pyruvate dehydrogenase E1 component,alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
suw
Staphylococcus aureus subsp. aureus TW20 (MRSA)
Pathway
suw00010
Glycolysis / Gluconeogenesis
suw00020
Citrate cycle (TCA cycle)
suw00620
Pyruvate metabolism
suw00785
Lipoic acid metabolism
suw01100
Metabolic pathways
suw01110
Biosynthesis of secondary metabolites
suw01120
Microbial metabolism in diverse environments
suw01200
Carbon metabolism
suw01210
2-Oxocarboxylic acid metabolism
Module
suw_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
suw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SATW20_10880 (pdhA)
00020 Citrate cycle (TCA cycle)
SATW20_10880 (pdhA)
00620 Pyruvate metabolism
SATW20_10880 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SATW20_10880 (pdhA)
Enzymes [BR:
suw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SATW20_10880 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
CBI48967
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Position
1159358..1160470
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AA seq
370 aa
AA seq
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MAPKLQAQFDAVKVLNDTQSKFEMVQILDENGNVVNEDLVPDLTDEQLVELMERMVWTRI
LDQRSISLNRQGRLGFYAPTAGQEASQLASQYALEKEDYILPGYRDVPQIIWHGLPLTEA
FLFSRGHFKGNQFPEGVNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQ
GDFYEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDA
LAVYQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVR
FRKFLENKGLWNEDKENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ
YEIYKEKESK
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
atggctcctaagttacaagcccaattcgatgcagtaaaagttttaaatgatactcaatcg
aaatttgaaatggttcaaattttggatgagaatggtaacgtcgtaaatgaagacttagta
cctgatcttacggatgaacaattagtggaattaatggaaagaatggtatggactcgtatc
cttgatcaacgttctatctcattaaacagacaaggacgtttaggtttctatgcaccaact
gctggtcaagaagcatcacaattagcgtcacaatacgctttagaaaaagaagattacatt
ttaccgggatacagagatgttcctcaaattatttggcatggtttaccattaactgaagct
ttcttattctcaagaggtcacttcaaaggaaatcaattccctgaaggcgttaatgcatta
agcccacaaattattatcggtgcacaatacattcaagctgctggtgttgcatttgcactt
aaaaaacgtggtaaaaatgcagttgcaatcacttacactggtgacggtggttcttcacaa
ggtgatttctacgaaggtattaactttgcagcagcttataaagcacctgcaattttcgtt
attcaaaacaataactatgcaatttcaacaccaagaagcaagcaaactgctgctgaaaca
ttagctcaaaaagcaattgctgtaggtattcctggtatccaagttgatggtatggatgcg
ttagctgtatatcaagcaactaaagaagcacgtgaccgcgcagttgcaggtgaaggtcca
acattaattgaaactatgacatatcgttatggtcctcatacaatggctggtgacgatcca
actcgttacagaacttcagacgaagatgctgaatgggagaaaaaagacccattagtacgt
ttccgtaaattccttgaaaacaaaggtttatggaatgaagacaaagaaaatgaagttatt
gaacgtgcaaaagctgatattaaagcagcaattaaagaggctgataacactgaaaaacaa
actgttacttctctaatggaaattatgtatgaagatatgcctcaaaacttagcagaacaa
tatgaaatttacaaagagaaggagtcgaagtaa
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