Streptomyces violascens: HWN34_21855
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Entry
HWN34_21855 CDS
T08842
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
svio
Streptomyces violascens
Pathway
svio00790
Folate biosynthesis
svio01100
Metabolic pathways
svio01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
svio00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HWN34_21855
Enzymes [BR:
svio01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HWN34_21855
6.3.2.17 tetrahydrofolate synthase
HWN34_21855
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QLA59006
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Position
5014699..5016225
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AA seq
508 aa
AA seq
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MSDHPPHDSGEPEQPGPDDEAFQEIVDAEQDRDPDLAVIEAGSRTLRTHTAPPQDEPVRP
ADPETAAALREVETELAGRWGETKLEPSVTRIQGLMDVLGDPQRAYPSIHITGTNGKTST
ARMIEALLGAFELRTGRYTSPHVQSITERISLDGAPIAPDRFVETYQDLKPYVEMIDNQG
EYRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGQVAVITPIDLDHTDRL
GNTPGEIAGEKAGIIKPDATVIMAQQPVDAAQVILKKAVEADATVAREGMEFGVVSRQIA
VDGQLVTLRGLGGEYEDIYLPLHGPYQAHNAAVALAAVEAFFGIGSEHARELDIDTLRKG
FASVTSPGRLEIVRKSPTVVLDAAHNPSGARATATAVTEAFDFSRLIGVVGVSDGKDAKG
LLEAFEPLLAEVVVTRNSSERAMDADALAALAVEVFGEDRVQVEPRLDDALEAAVTLAEE
EGEYSGGGVLVTGSVITVGEARLLLGRG
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgaccaccccccgcacgacagcggcgagcccgagcagcccggacccgatgacgag
gccttccaggagatcgtcgacgcagaacaggaccgcgaccccgacctcgccgtgatcgag
gcgggcagccgcaccctgcgcacccacaccgctccgccgcaggacgagccggtccgcccc
gccgaccccgagaccgccgccgcgctgcgcgaggtcgagacggaactggccggccgctgg
ggcgagaccaagctggagccctccgtcacccgtatccaggggctgatggacgtgctgggc
gacccgcagcgcgcgtacccctcgatccacatcaccgggaccaacggcaagacctccacg
gcccgcatgatcgaggcgctgctcggcgccttcgagctgcgcaccgggcggtacacctcg
ccgcacgtccagtcgatcaccgagcggatcagcctggacggcgcgccgatcgcccccgac
cggttcgtcgagacctaccaggacctcaagccctacgtcgagatgatcgacaaccagggc
gagtaccggctctccttcttcgaggtgctcaccgggatggcctacgcggccttcgcggac
gcgccggtggacgtcgccgtggtcgaggtcggcatgggcggcagctgggacgcgaccaac
gtcatcgacggccaggtcgcggtcatcaccccgatcgacctggaccacaccgaccggctc
ggcaacacgcccggcgagatcgccggtgagaaggccgggatcatcaagcccgacgccacc
gtgatcatggcgcagcagcccgtcgacgccgcccaggtcatcctcaagaaggccgtggag
gccgacgcgacggtggcccgcgagggtatggagttcggcgtggtctcccggcagatcgcc
gtcgacggccagctggtcaccctgcgcgggctcggcggcgagtacgaggacatctacctg
ccgctgcacgggccctaccaggcgcacaacgcggcggtcgcgctcgccgccgtcgaggcg
ttcttcggcatcggctccgagcacgcccgcgagctggacatcgacaccctgcgcaagggg
ttcgcctcggtgacctcgccgggccgcctggagatcgtccgcaagtcgccgacggtcgtc
ctggacgccgcccacaacccctcgggcgcccgcgccaccgcgaccgccgtcaccgaggcg
ttcgacttcagccgcctgatcggcgtggtcggggtgagcgacggcaaggacgccaagggg
ctcctcgaagccttcgagccgctcctcgccgaggtcgtcgtcacccgcaactccagcgag
cgggcgatggacgccgacgcgctggcggcgctcgccgtcgaggtcttcggcgaggaccgc
gtccaggtcgagccgcggctcgacgacgccctggaggcggcggtcaccctcgccgaggaa
gagggcgagtactccggcggtggcgtcctcgtcaccggctccgtcatcacggtcggcgag
gcccggctgcttctgggaaggggctga
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