Streptomyces vinaceus: CP980_22205
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Entry
CP980_22205 CDS
T06865
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
svn
Streptomyces vinaceus
Pathway
svn00790
Folate biosynthesis
svn01100
Metabolic pathways
svn01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
svn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CP980_22205
Enzymes [BR:
svn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CP980_22205
6.3.2.17 tetrahydrofolate synthase
CP980_22205
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QEV47423
UniProt:
A0A5J6JBD7
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Position
4911339..4912868
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AA seq
509 aa
AA seq
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MSEQQPESNGPDDRDETSDLFERIVAEESDRDPDLAVIEAGSRTLRAQAGPPQGDPVPSQ
PLDPEVARALQEVEQELSTRWGETKLEPSVTRIAALMDVLGEPQRAYPSIHVTGTNGKTS
TARMIEALLNAFELRTGRYTSPHVQSVTERISLDGAPITAERFVETYHDIKPYVEMVDAA
EEYRLSFFEVLTGMAYAAFADAPVDAAVVEVGMGGTWDATNVIDGAVAVITPISLDHTDR
LGSTPGEIAQEKGGVIKQDATVILAQQPVDAAQVLLKKAVEVDATVAREGMEFGVVSREV
AVGGQMLTLRGVGGEYDGIFLPLYGAHMAHNAAVALAAVEAFFGVGAQQSRELDLETVRR
AFASVTSPGRMEVVRRSPTVVLDAAHNPAGAQVTAEAVTEAFGFSRLIGVMAASEGKDVK
GVLEAFEPIFAEIVVTENSSHRAMSADELAAVAVEVFGPDRVQVEPRLDDALEAAITLAE
EEAEYGGAGVLVTGSVITVGEARLLLKRG
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagcagcagcccgagagcaacggacccgacgaccgcgacgagacctccgatctc
ttcgaacggatcgtggccgaagagtccgaccgcgaccccgacctggcggtgatcgaggcc
ggcagccgcaccctgcgcgcccaggccggaccgccccagggcgacccggtaccgtcgcag
cccctcgacccggaggtggcgcgggcgctccaggaggtggagcaggagctctccacccgc
tggggcgagaccaagctggagccgtccgtcacgcggatcgccgcgctgatggacgtgctg
ggcgaaccgcagcgcgcgtacccctccatccacgtcaccggcaccaacggcaagaccagc
accgcgcgcatgatcgaggccctgctgaacgccttcgaactgcgcaccggtcgctacacc
agcccgcacgtgcagtcggtcaccgaacggatcagcctcgacggggcgccgatcaccgcc
gagcgcttcgtcgagacgtaccacgacatcaagccgtacgtggagatggtcgacgccgcc
gaggagtaccggctgtccttcttcgaggtgctcaccggcatggcgtacgcggccttcgcg
gacgcgccggtggacgcggccgtcgtcgaggtcggcatgggcggtacctgggacgcgacc
aacgtgatcgacggcgcggtcgccgtcatcaccccgatcagcctggaccacacggaccgg
ctcggctccacgcccggggagatcgctcaggagaagggcggcgtcatcaagcaggacgcc
accgtgatcctggcgcagcagccggtggacgcggcgcaggtgctgctgaagaaggccgtc
gaggtggacgcgaccgtggcccgcgagggcatggagttcggcgtcgtctcgcgcgaggtg
gccgtcggcgggcagatgctgacgctgcgcggcgtgggcggcgagtacgacgggatcttc
ctgccgctgtacggggcccacatggcccacaacgcggcggtggcgctggcggcggtcgag
gccttcttcggcgtcggggcgcagcagtcgcgggagctggacctggagaccgtacgccgg
gccttcgcctcggtgacctcgccgggccggatggaggtcgtacggcgcagcccgacggtg
gtcctggacgcggcgcacaacccggccggcgcacaggtcacggcggaggcggtgaccgag
gccttcggcttcagccggctgatcggggtcatggcggcgagcgagggcaaggacgtcaag
ggggtcctggaggccttcgagccgatcttcgcggagatcgtcgtcacggagaactccagc
caccgggcgatgtccgccgacgagctggcggcggtcgcggtcgaggtcttcgggccggac
cgggtgcaggtggagccgcggctggacgacgccctggaggcggcgatcaccctggcggag
gaagaggccgagtacggaggggccggggtcctggtgaccggttccgtgatcacggtgggc
gaggcccgcctgctgctgaagaggggctga
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