Streptomyces viridifaciens: CP971_22550
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Entry
CP971_22550 CDS
T06960
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
svr
Streptomyces viridifaciens
Pathway
svr00790
Folate biosynthesis
svr01100
Metabolic pathways
svr01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
svr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CP971_22550
Enzymes [BR:
svr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CP971_22550
6.3.2.17 tetrahydrofolate synthase
CP971_22550
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QEV04153
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All DBs
Position
5112254..5113645
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AA seq
463 aa
AA seq
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MSDKADPNPYTLRPAEGDTGDALRDVELELSKRWPENKLEPSLDRIEALMDILGQPQRAF
PSIHITGTNGKTSTARMIEQLLNTFELRTGRYTSPHVETVTERISLDGAPISPERFVEVY
RDIEPYVQMVDAAQPVPMSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDAAV
AVITPIGLDHTDKLGETTGAIAVEKSGIIKSGAVAVVAQQQLDAAETILRRAVEVDATVA
REGMEFGVIRRELAVGGQLVTLRGLGGEEYEDVFIPLHGEHQAHNAALALAAVEAFFGVG
GARGGQLDADKVRQGFSGVSSPGRLEVVRRSPTIILDAAHNPHGARATVAAISESFGFTR
LVGVIGTSGDKDVAGVLEAFEPILAEVVVTRNSTHRAMDVDALAALAVEVFGEDRVQVEP
RLDDAIAAAVTLAEEEGDLGGAGVLVTGSVITVGEARLLLGRK
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgacaaggccgacccgaacccgtacaccctccgccccgccgagggcgacaccggc
gacgccctgcgcgacgtcgaactcgaactctccaagcgctggccggagaacaagctggag
ccctcgctcgaccggatcgaggcgctgatggacatcctgggccagccccagcgggccttc
ccgtccatccacatcaccggcaccaacggcaagacctccaccgcccggatgatcgagcag
ctgctcaacaccttcgagctgcgcaccggccgctacaccagcccgcacgtggagaccgtc
accgagcggatcagcctggacggcgccccgatcagccccgagcgcttcgtcgaggtctac
cgcgacatcgagccctacgtgcagatggtcgacgccgcccagccggtgccgatgtccttc
ttcgaggtgctcaccggcatggcctacgcggccttcgccgacgcgccggtggacgtcgcg
gtggtcgaggtcggcatgggcggctcctgggacgccaccaacgtcatcgacgccgccgtc
gccgtgatcaccccgatcgggctggaccacaccgacaagctcggcgagaccaccggcgcc
atcgcggtcgagaagtccgggatcatcaagtccggcgccgtcgccgtggtcgcccagcag
cagctggacgccgccgagaccatcctgcgccgggccgtcgaggtggacgccaccgtggcc
cgcgagggcatggagttcggcgtgatccgccgtgagctcgccgtcggcggccagctggtg
acgctgcgcggactcggcggcgaggagtacgaggacgtcttcatcccgctgcacggcgag
caccaggcgcacaacgcggcgctggcgctggccgcggtcgaggccttcttcggcgtcggc
ggcgcccgcggcggccagctggacgccgacaaggtccgccagggcttctccggcgtctcc
tcgcccggccgcctcgaggtcgtccgccgcagtcccacgatcatcctggacgccgcgcac
aacccgcacggcgcccgggccaccgtcgccgcgatctccgagtccttcggcttcacccgc
ctggtcggcgtgatcggcacctcgggggacaaggacgtggccggcgtgctggaggccttc
gagccgatcctggccgaggtcgtcgtgacccggaactccacccaccgcgcgatggacgtg
gacgcgctcgcggccctggccgtcgaggtcttcggcgaggaccgggtccaggtcgagccg
cggctcgacgacgccatcgccgccgcggtcaccctggccgaggaggagggcgacctcggc
ggcgccggggtgctggtcaccggttcggtcatcacggtgggcgaggcccgcctgctgctc
gggaggaagtga
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