Thauera aromatica: Tharo_1192
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Entry
Tharo_1192 CDS
T05381
Name
(GenBank) Dihydrofolate synthase / Folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tak
Thauera aromatica
Pathway
tak00790
Folate biosynthesis
tak01100
Metabolic pathways
tak01240
Biosynthesis of cofactors
Module
tak_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
tak00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Tharo_1192
Enzymes [BR:
tak01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Tharo_1192
6.3.2.17 tetrahydrofolate synthase
Tharo_1192
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AVR88123
UniProt:
A0A2R4BLP6
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Position
1253535..1254830
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AA seq
431 aa
AA seq
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MPDTLAGWLDLLEQRHGQRIELGLERVRTVRAAMGAPSDAVLITVGGTNGKGSCCAMLES
ILLAAGYRVGCYTSPHLLRYNERVRIDGKDADDARLVAAFAAVEAARGATPLTYFEHGTL
AAWALFAAERPDVIILEVGLGGRLDAVNVFDADCAIVTGVAMDHMEYLGDTREKIGFEKA
GIFRAGRPAVCGDPQPPASLLEHARAIGAELWVSGRDFGFGGDRQQWGYWRYALPAAQGA
LLRRGGLAYPALRGANQLLNAAAVLTALECLRQRLPVSMQHVRQGLMLVDVPGRFQVLPG
RPAVVLDVAHNPQAAGVLAENLGNMGFYPETWAVLGMLGDKDVAGVVARMADRVDHWLLA
DLPGPRGLSAQALAERVREAGGRGDLHCFGSPADAFVAAQEGAAEGDRIVAFGSFLTVAD
VLAALRAARHG
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
ttgccggacacgctggccggttggctcgacctcctcgaacagcgccacgggcagcgcatc
gagctcggcctcgagcgcgtgcgcacggtgcgggcggcgatgggcgcgccgtcggacgcg
gtattgatcaccgtcggcggcaccaacggcaagggctcgtgctgcgcgatgctcgagagc
atcctgctcgccgccggctaccgggtcggttgctacacttcgccccacctgctgcgctac
aacgagcgcgtgcgtatcgacggcaaggatgcggacgatgcccgcctcgtcgccgcattc
gccgcggtcgaggcggcgcgcggcgccaccccgctgacctacttcgagcacggcacgctc
gccgcctgggcgctgttcgccgccgagcgcccggacgtgatcattctcgaagtcggcctg
ggcgggcgcctggacgcggtcaacgtgttcgacgccgactgcgcgatcgtcaccggcgtg
gcgatggaccacatggagtatctcggcgacacgcgcgagaagatcggcttcgagaaggcc
ggcattttccgcgctggccggcccgcggtatgcggcgacccgcagccgccggcgagcctg
ctcgagcatgcacgcgcgatcggtgccgaactgtgggtcagcggccgggacttcggcttc
ggcggcgaccgccagcagtggggctactggcgctatgcgctgcctgccgctcagggcgcg
ctgcttcggcgcggcgggctggcgtacccggcgctgcgcggggccaaccagctgctcaac
gctgccgccgtgctcaccgcgctggaatgcctgaggcagcgcctgccggtgtcgatgcag
cacgttcgccagggcctgatgctggtcgacgtgccggggcgcttccaggtgctgccgggg
cgaccggcggtggtgctcgatgtcgcgcacaatccgcaagccgccggcgtgctcgcggaa
aacctcggcaacatggggttttatcccgaaacctgggcagtgctgggcatgctcggcgac
aaggatgttgccggcgtggtggcgcggatggccgaccgggtcgatcactggctgctggcc
gacctgcccgggccgcgcggcctgtcggcgcaggcgctggccgagcgggtgcgcgaggcc
ggtggcaggggggatctgcattgtttcggctcgcctgcagacgcgtttgttgcagcgcag
gagggggctgccgagggtgatagaatcgtggccttcggttccttcctgacggtggcggac
gtgcttgcagcgctcagggctgcgcggcacgggtga
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