Trachypithecus francoisi (Francois's langur): 117078518
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Entry
117078518 CDS
T07225
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn00010
Glycolysis / Gluconeogenesis
tfn00020
Citrate cycle (TCA cycle)
tfn00620
Pyruvate metabolism
tfn00785
Lipoic acid metabolism
tfn01100
Metabolic pathways
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Carbon metabolism
tfn01210
2-Oxocarboxylic acid metabolism
tfn04066
HIF-1 signaling pathway
tfn04922
Glucagon signaling pathway
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Central carbon metabolism in cancer
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Diabetic cardiomyopathy
Module
tfn_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
117078518 (PDHA1)
00020 Citrate cycle (TCA cycle)
117078518 (PDHA1)
00620 Pyruvate metabolism
117078518 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
117078518 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
117078518 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
117078518 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
117078518 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
117078518 (PDHA1)
Enzymes [BR:
tfn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
117078518 (PDHA1)
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
DUF1117
Motif
Other DBs
NCBI-GeneID:
117078518
NCBI-ProteinID:
XP_033057968
LinkDB
All DBs
Position
Unknown
AA seq
433 aa
AA seq
DB search
MTLSRRAATEAWRLLGHLKETLGHPRRASWAVRSRRCRQCLCFMRKMLAAVSRVLSGASQ
KPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELK
ADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAE
LTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDG
AANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGM
DILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPI
MLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEV
RGANQWIKFKSVS
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgactctgtcacgtcgcgctgcgactgaggcgtggcgtctgctggggcacctgaaggag
actttgggacacccgcgtcgtgcctcttgggctgtgaggagtcgccgctgccgccagtgc
ctgtgcttcatgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcag
aagccggcaagcagagtgctggtagcatcccgtaattttgcaaatgatgctacatttgaa
attaagaaatgtgaccttcaccgactggaagaaggccctcctgtcacaacagtgctcacc
agggaggatgggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaa
gcagatcagctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcag
gaagcttgctgtgtgggcctggaagccggcatcaaccccacagaccatctcataacagcc
taccgggctcacggctttaccttcacccggggcctttccgtccgagaaattctcgcagag
cttacaggacgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgcc
aagaacttctacgggggcaatggcatcgtgggagcgcaggtgcccctgggcgctgggatt
gctctagcctgtaagtataatggaaaagatgaggtctgcctgactttatacggcgatggt
gctgctaaccagggccagatattcgaagcttacaacatggcagctttgtggaaattacct
tgtattttcatctgtgagaataatcgctatggaatgggaacatctgttgagagagcagca
gccagcactgattactacaagagaggcgatttcattcctgggctgagagtggatggaatg
gatatcctgtgcgtccgagaggcgacaaagtttgctgctgcctattgtagatctgggaag
gggcccatcctgatggagctgcagacttatcgttaccacggacacagtatgagtgatcct
ggagtcagttaccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctatt
atgcttctcaaggacaggatggtgaacagcaatcttgccagtgtggaagaactaaaggaa
attgatgtggaagtgaggaaggagattgaggatgctgcccagtttgccacggccgatcct
gagccacctttggaggagctgggctaccacatctactccagtgacccacctttcgaagtt
cgtggtgccaatcagtggatcaagtttaagtcagtcagttaa
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