KEGG   Trachypithecus francoisi (Francois's langur): 117086074
Entry
117086074         CDS       T07225                                 
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
tfn  Trachypithecus francoisi (Francois's langur)
Pathway
tfn00562  Inositol phosphate metabolism
tfn01100  Metabolic pathways
tfn01521  EGFR tyrosine kinase inhibitor resistance
tfn04068  FoxO signaling pathway
tfn04070  Phosphatidylinositol signaling system
tfn04071  Sphingolipid signaling pathway
tfn04115  p53 signaling pathway
tfn04140  Autophagy - animal
tfn04150  mTOR signaling pathway
tfn04151  PI3K-Akt signaling pathway
tfn04218  Cellular senescence
tfn04510  Focal adhesion
tfn04931  Insulin resistance
tfn05165  Human papillomavirus infection
tfn05166  Human T-cell leukemia virus 1 infection
tfn05200  Pathways in cancer
tfn05206  MicroRNAs in cancer
tfn05208  Chemical carcinogenesis - reactive oxygen species
tfn05213  Endometrial cancer
tfn05214  Glioma
tfn05215  Prostate cancer
tfn05218  Melanoma
tfn05222  Small cell lung cancer
tfn05224  Breast cancer
tfn05225  Hepatocellular carcinoma
tfn05230  Central carbon metabolism in cancer
tfn05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tfn05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:tfn00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    117086074 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    117086074 (PTEN)
   04070 Phosphatidylinositol signaling system
    117086074 (PTEN)
   04071 Sphingolipid signaling pathway
    117086074 (PTEN)
   04151 PI3K-Akt signaling pathway
    117086074 (PTEN)
   04150 mTOR signaling pathway
    117086074 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    117086074 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    117086074 (PTEN)
   04218 Cellular senescence
    117086074 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    117086074 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117086074 (PTEN)
   05206 MicroRNAs in cancer
    117086074 (PTEN)
   05208 Chemical carcinogenesis - reactive oxygen species
    117086074 (PTEN)
   05230 Central carbon metabolism in cancer
    117086074 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    117086074 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    117086074 (PTEN)
   05214 Glioma
    117086074 (PTEN)
   05218 Melanoma
    117086074 (PTEN)
   05215 Prostate cancer
    117086074 (PTEN)
   05213 Endometrial cancer
    117086074 (PTEN)
   05224 Breast cancer
    117086074 (PTEN)
   05222 Small cell lung cancer
    117086074 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    117086074 (PTEN)
   05165 Human papillomavirus infection
    117086074 (PTEN)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    117086074 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    117086074 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    117086074 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:tfn01009]
    117086074 (PTEN)
Enzymes [BR:tfn01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     117086074 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     117086074 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     117086074 (PTEN)
Protein phosphatases and associated proteins [BR:tfn01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    117086074 (PTEN)
SSDB
Motif
Pfam: PTEN_C2 DSPc Y_phosphatase PTPlike_phytase Y_phosphatase3 DUF3256
Other DBs
NCBI-GeneID: 117086074
NCBI-ProteinID: XP_033071476
LinkDB
Position
Unknown
AA seq 385 aa
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCSPTRREDKFMYFEFPQPLPVCGDIKVEFF
HKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVL
TLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYR
YSDTTDSDPENEPFDEDQHTQITKV
NT seq 1158 nt   +upstreamnt  +downstreamnt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatgggatttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctttgtgctgaaagacattatgacaccgccaaa
tttaattgcagagttgcacaatatccttttgaagaccataacccaccacagctagaactg
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcacctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcagccccacacgacgggaagacaagttc
atgtactttgagttccctcagccgttacctgtgtgtggtgatatcaaagtagaattcttc
cacaaacagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaatacattc
ttcataccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaa
gaaattgatagcatttgcagtatagagcgtgcagataatgacaaggaatatctagtactt
actttaacaaaaaatgatcttgacaaagcaaataaagacaaagccaaccgatacttttct
ccaaattttaaggtgaagctgtacttcacaaaaacagtagaggagccgtcaaatccagag
gctagcagttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattataga
tattctgacaccactgactctgatccagagaatgaaccttttgatgaagatcagcataca
caaattacaaaagtctga

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