Thermobifida fusca: Tfu_3049
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Entry
Tfu_3049 CDS
T00265
Name
(GenBank) pyruvate dehydrogenase (lipoamide)
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
tfu
Thermobifida fusca
Pathway
tfu00010
Glycolysis / Gluconeogenesis
tfu00020
Citrate cycle (TCA cycle)
tfu00620
Pyruvate metabolism
tfu00785
Lipoic acid metabolism
tfu01100
Metabolic pathways
tfu01110
Biosynthesis of secondary metabolites
tfu01120
Microbial metabolism in diverse environments
tfu01200
Carbon metabolism
tfu01210
2-Oxocarboxylic acid metabolism
Module
tfu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tfu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Tfu_3049
00020 Citrate cycle (TCA cycle)
Tfu_3049
00620 Pyruvate metabolism
Tfu_3049
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Tfu_3049
Enzymes [BR:
tfu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Tfu_3049
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AAZ57082
UniProt:
Q47KE0
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All DBs
Position
3565896..3566993
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AA seq
365 aa
AA seq
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MADTAKPKATGKTGSRRRAARNNADSHFNGEKPEVLLDYYRQMLLIRRFEERAAQAYTQA
RIGGYCHLNLGEEATIVGLMEALQERDYLFTNYREHGYAIAKGTHPREVMAELYGRSTGV
SKGWGGSMHLFDARTRLLGGYGIVGGQLPLAVGAALAITYRGSDEVVMCQMGDGTTNIGA
FHESLNIASLWNLPVIFVVINNFTGMGTPVERSSAEPELYKRGSAYRIEGVRVDGRDVLA
VRDTATTLVERARSEHRPFLLEAFSYRMKGHSVVDPAKYRTKEEAEEALANDPIAMFEER
LTEAGILTDEIKKEIAESVKAEVADAADFAENSPHPEVSTLFDYTYATPVANESRRMPAD
PVFAE
NT seq
1098 nt
NT seq
+upstream
nt +downstream
nt
atggctgacacggccaagccgaaggcgaccggcaagaccggttctcgccgccgcgcggcc
cgtaataacgccgactctcacttcaacggtgagaagcccgaagtactcctcgactactac
cggcagatgctgctgatccgccgcttcgaggagcgtgccgcgcaggcctacacccaggcg
cgtatcggtggctactgccacctcaacctcggtgaagaagccaccatcgtcggtctcatg
gaggcgctccaggagcgcgactacctcttcaccaactaccgggaacacggctacgccatc
gccaaaggcacccatccgcgggaagtgatggcagagctctacggccgctccaccggcgtc
tccaagggctggggcggctccatgcacctgttcgacgcccgaacccgcctcctgggcggc
tacggcatcgtcggcggccaactgccgctcgccgtcggcgctgccctcgccatcacctac
cggggcagcgacgaagtcgtcatgtgccagatgggcgacggcaccaccaacatcggcgcg
ttccacgagtcgctgaacatcgccagcctgtggaacctgccggtgatcttcgtggtgatc
aacaacttcaccggtatgggcacgccggtcgagcgctcctcggcagagcccgaactgtac
aagcgcggctccgcttaccggattgaaggggtgcgcgtcgacggccgggacgtcctcgcc
gtccgcgacaccgccaccacactggtggagcgggcccgcagcgaacaccgccccttcctg
ctggaagccttcagctaccggatgaaaggccactccgtggtggacccggccaagtaccgc
accaaggaggaggcggaggaggccctcgccaacgatccgatcgccatgttcgaagaacgc
ctgaccgaggcgggcattctcaccgacgagatcaaaaaggagatcgccgaatcggtgaaa
gccgaggtcgccgacgccgccgatttcgcggagaacagcccgcaccccgaggtgtccacg
ctgttcgactacacctacgccaccccggtggccaacgagtcgcgccggatgcccgccgac
ccggtgttcgccgagtag
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