Theropithecus gelada (gelada): 112625013
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Entry
112625013 CDS
T08041
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00010
Glycolysis / Gluconeogenesis
tge00020
Citrate cycle (TCA cycle)
tge00620
Pyruvate metabolism
tge00785
Lipoic acid metabolism
tge01100
Metabolic pathways
tge01200
Carbon metabolism
tge01210
2-Oxocarboxylic acid metabolism
tge04066
HIF-1 signaling pathway
tge04922
Glucagon signaling pathway
tge05230
Central carbon metabolism in cancer
tge05415
Diabetic cardiomyopathy
Module
tge_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
112625013 (PDHA2)
00020 Citrate cycle (TCA cycle)
112625013 (PDHA2)
00620 Pyruvate metabolism
112625013 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
112625013 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
112625013 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
112625013 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
112625013 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
112625013 (PDHA2)
Enzymes [BR:
tge01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
112625013 (PDHA2)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
112625013
NCBI-ProteinID:
XP_025241968
Ensembl:
ENSTGEG00000003743
LinkDB
All DBs
Position
5:complement(46013874..46015250)
Genome browser
AA seq
391 aa
AA seq
DB search
MKKMLTALISRVLRRVAQKSARRVLVASRNSSNDATFEIEKCDLHLLEEGPPVTTVLTRA
EGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHLITSYR
AHGMCYTRGLSVQSILTELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIAL
ACKYKGNNEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYAMGTSAERAAAS
TDYYKRGNFIPGLKVDGMDVLCVREATKFAADYCRSGKGPILMELQTYRYHGHSMSDPGV
SYRTREEIQEVRSKRDPIVILQDRMVNSKLATVEELKEIGTEVKKEIDDAAQFATSDPEP
RLEELGHHIYSSDSSFEVRGANPWIKFKSVS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaatgctgaccgccctcatctcccgcgtgttgaggcgagttgcccagaagtca
gctcgcagagtgctggtggcatcccgtaattcctcaaatgacgctacatttgaaattgag
aaatgtgatcttcacctgttggaggagggtccccccgtcactacagtgctcactagggcg
gaggggcttaaatactacaggatgatgctgactgttcgccgcatggaattgaaggcagat
cagctgtacaaacagaaattcattcgtggtttctgtcacctgtgcgatggtcaggaagct
tgctgcgtgggccttgaggctggaataaacccctcggatcacctcatcacatcctatagg
gctcatggtatgtgctatactcggggactttctgtccaatccattctcacagagctgacg
ggaagaagaggaggttgtgctaaaggaaaaggaggatcgatgcatatgtataccaagaac
ttctacgggggcaatggcatcgtcggagcgcagggccccctgggcgctggcattgctctg
gcctgtaaatataagggaaacaatgagatctgtttgactttatatggggatggcgctgcg
aatcaggggcagatagccgaagctttcaatatggcagctttatggaaattaccttgtgtt
ttcatctgtgagaataacctatatgcaatgggaacatctgctgagagagcagcagccagc
actgattactacaagaggggcaattttatccctgggctaaaagtcgatggaatggatgtt
ctatgtgttcgtgaggcaacaaaatttgcagctgactactgtaggtctggaaaggggccc
atactgatggagctgcagacctaccgttatcatggacacagtatgagtgatcctggagtc
agttatcgtacacgagaagaaattcaggaagtaagaagtaagagggatcctatagtgatt
ctccaagatagaatggtaaacagcaagctcgccactgtcgaagaattaaaggaaattggg
actgaggtgaagaaagaaattgatgatgctgcccagtttgctaccagtgatcctgagcca
cgtctggaagaattaggccatcacatctacagcagtgattcatcttttgaagttcgtggt
gcaaatccatggatcaagtttaagtccgtcagttaa
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