Theropithecus gelada (gelada): 112631314
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Entry
112631314 CDS
T08041
Name
(RefSeq) aldo-keto reductase family 1 member C4
KO
K00037
3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:
1.1.1.50
1.1.1.357
1.1.1.225
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00120
Primary bile acid biosynthesis
tge00140
Steroid hormone biosynthesis
tge01100
Metabolic pathways
tge05208
Chemical carcinogenesis - reactive oxygen species
Module
tge_M00104
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
tge_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
112631314
00140 Steroid hormone biosynthesis
112631314
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
112631314
Enzymes [BR:
tge01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
112631314
1.1.1.225 chlordecone reductase
112631314
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
112631314
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Motif
Pfam:
Aldo_ket_red
Motif
Other DBs
NCBI-GeneID:
112631314
NCBI-ProteinID:
XP_025252036
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All DBs
Position
9:4870341..4883566
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AA seq
202 aa
AA seq
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LQPGETPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIRVSNFNRRQLEMILNNPG
LKYKPICNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPVL
CALAKKHKRSPALIALRYQLQRGVVVLAKNYNEQRITENVQVFEFQLTSEDMKVLDGLNR
NFRYAVMDFLVVHPDYPFSDEY
NT seq
609 nt
NT seq
+upstream
nt +downstream
nt
cttcagccaggtgagacgccactaccaaaagatgaaaatggaaaagtaatgttcgacaca
gtggatctctgtgccatatgggaggccatggagaagtgtaaggatgcaggattggccaag
tccatccgggtgtcaaacttcaaccgcagacagctggagatgatcctcaacaacccagga
ctcaagtacaagcccatctgcaaccaggtggaatgtcatccttacctcaaccagagcaaa
ctgctggatttctgcaagtcaaaagacattgtcctggttgcccatagtgctctgggaacc
caacgacataaactatgggtggaccagaactccccagctcttttggaggacccagttctt
tgcgccttagcaaagaaacacaaacgatccccagccctgattgccctgcgctaccagctg
cagcgtggggttgtggtcctggccaagaactacaatgagcagcggatcacagaaaacgtc
caggtttttgaattccagttgacttcggaggatatgaaagttctagatggcctaaacaga
aattttcgatatgctgtcatggattttcttgtggtccaccctgattatccattttcagat
gaatattag
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