Toxoplasma gondii: TGME49_232590
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Entry
TGME49_232590 CDS
T01093
Name
(RefSeq) glutamate-cysteine ligase, catalytic subunit domain-containing protein
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
tgo
Toxoplasma gondii
Pathway
tgo00270
Cysteine and methionine metabolism
tgo00480
Glutathione metabolism
tgo01100
Metabolic pathways
tgo01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
tgo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
TGME49_232590
09106 Metabolism of other amino acids
00480 Glutathione metabolism
TGME49_232590
Enzymes [BR:
tgo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
TGME49_232590
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Gene cluster
GFIT
Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
7898887
NCBI-ProteinID:
XP_002368128
UniProt:
A0A125YWW8
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Position
VIII:complement(join(2177059..2178252,2178787..2179377,2179815..2179985,2180555..2180742,2181168..2181295,2181691..2182007,2182555..2182931,2183293..2183355,2183723..2183882))
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AA seq
1062 aa
AA seq
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MGFLEEGAPLAWRDSDRYRATVKRRGVREFVKLFRHFKDSHCDRSSLSWGDELEFCLVKL
DYGSQIPRIFLAAECALHELRSREALLSKALTWKPSPTWRCVLNSLTQPISHRLGSAESG
GPSTSFSPLDAVLAFSALSNQSGDTTCSISANAPVWQLSGWHPEYGRHMVEAIPEKPFPL
DLESLIYLLPSMQIRRKKIQAVLPADCYVVSLTNFPTLGALVSDLDASTDSEKNQNGGSR
GDTNETGGGTHEGQRATNSGILKPGDFAFPAAVPDPFRGCSRSIFVGDEVIQKHPRFRTL
TANIRERRGKKVDITVPLFQDVCTFPRADRIDGSRTPAGDSAKAKTLHEQEYRRQLMMEG
KTLHDGRSIYMDHMVFGMGMHCAQATFGCPSLSDARYLYDQLGVLAPLWLSLTAATPFLR
GLVAATDTRWATIAGAVDCRTSKESRALPKSRYGAFSLYIGDHGSLHDHIDFYNDIPAPV
NRRAYAALVASGVDPVLARHVAFLFVRDPMVIFRDKLVDCQGEEEEEAIRRLEAEARVDW
AVDVYDGKYQTTADFENLQSTNWNSVRFKPPPSFNQFVGQAVGQTSKPLTAHEGGTQNEF
TETNERRQLRNEDKESPGATAQRLCRSGTTGPTVECWRVEFRTPEIQLSDFENAACIALI
TVFVQVLLEERFDLYIPMSLNDENMRRSSQLNSILTQKFWFRKDIRSSSSDRSFEEFYLH
EILFGVPVVPGRQTPAVALVPACLAYMERRLPSGSPYAAAQLLEFFDFLRHRTQGIVPTN
ATFLRAYLAAHPDYKHDSVVSRTISFGVCDLAAKIGHGTVRIPELFGPFAHRVGMRISDD
ESIQAYGDFSKPLVTADFPCPLGGFLASVREQHCEKGPAEAEPHSSVSGMNQKTPENLLC
NHSAGASFSPEKYGLCLSRRTKMDPPQSDPGLSFYLGGRVPLTLQKAWKSQQIQRFFDFR
NENSISKMEMREFRIHKDVWNPVQREFRGSSHRPITTNKAESTWAWMLSTAVGGPDTDTG
ASDENGSTSCPSLGEIGDISDEAQAEKRYNGAREQEGACSQG
NT seq
3189 nt
NT seq
+upstream
nt +downstream
nt
atggggttcctggaggaaggcgcgccactagcatggagagactcggacagatacagagcc
acagtgaaacggcgcggtgtccgtgaattcgtaaaactctttcggcacttcaaggacagc
cactgtgatcggtccagtctctcgtggggcgacgaactagagttctgcctcgtcaagctg
gactacggctctcaaattcctcggattttcttggccgccgaatgcgcgttacacgaacta
cggtcaagagaagctttgctgtctaaggctctcacgtggaaaccgtcgccgacgtggcgt
tgcgtgttgaattcgctgactcaaccgatttcccacaggttgggttcggcggaaagcgga
ggtcccagcacttccttctccccattggacgcagtccttgcattttctgcgttatccaac
cagagcggcgacacgacgtgcagcatctccgctaacgctcccgtgtggcagctcagtgga
tggcaccctgaatatgggcggcacatggtcgaggccatcccagaaaaaccttttcctctg
gacttagagtcgctcatctacctccttccctccatgcagatacgacgcaaaaagatccag
gctgtccttcccgcagactgctacgtagtctcgctgacgaactttcccactctaggtgca
cttgtctcggaccttgacgccagcactgactctgagaagaatcagaacggaggctcccgc
ggcgatacgaacgaaactggaggtggtactcatgagggtcaacgcgccacgaactccggt
atattgaagcctggagattttgcgtttcccgccgccgtgcctgatccgtttcgcggctgc
agcaggagcatttttgtcggcgacgaggtcatccaaaagcacccgcggttccgcactctt
accgcgaacatccgagagcggcgaggcaaaaaagtcgacatcaccgttccgctgtttcag
gatgtctgcacgtttccccgtgctgatcggatagacggaagccgcacgcctgccggcgat
tcagcgaaggcgaaaacgctgcacgagcaggagtatcggcggcaactcatgatggaggga
aagactctgcatgatgggcggtcgatttacatggaccacatggtcttcggcatgggcatg
cattgcgcacaagctacttttggctgcccgtcgctttccgatgcacggtatctctacgat
cagttgggtgtccttgctcctttgtggctttcgctgacagcggcgactccatttcttcga
gggctcgtcgcggcgacggacacacgctgggcgacaattgccggcgcggtggattgtcgc
acttcgaaggagtccagggctctgccaaagtctcgttacggagcattttcgctgtacatc
ggcgaccacggttctttacatgatcatatcgacttctacaacgacattcctgcccccgtg
aaccgacgggcgtatgcggctttagtcgctagtggagtggatcctgttctcgctcgccat
gtcgcgtttttgtttgtgcgggaccccatggtaatctttcgagacaagcttgtcgactgc
cagggcgaagaagaggaagaagcaattcggcgcctggaggcagaagcacgggttgactgg
gcggtggacgtgtatgacggaaagtaccagactaccgcagacttcgagaaccttcagtcg
acaaactggaattctgtgcgtttcaaacctccaccgtcgttcaaccaattcgtcggacaa
gctgtgggacagacatcaaaacccctgacagcacacgaaggtggaacgcagaatgagttc
acagagacgaacgaaaggcggcaactgaggaatgaggacaaagaaagtcctggcgcaact
gcacagagactttgcagaagcggcacaactggacccaccgttgagtgttggagggtcgag
ttccgaacacccgagatccagctatcggactttgaaaatgctgcatgcattgcgctcatt
acagtctttgtgcaggttcttttggaggaacgtttcgacttgtatattccaatgtccttg
aacgacgagaacatgcggcgttcaagtcagctgaactcgatcctgacacagaagttttgg
ttccgtaaagacatccgatcgagttcgtccgatcgctcttttgaagagttctaccttcat
gaaattctttttggcgttcccgtggtgcccggacgccaaacgcctgccgttgctcttgtt
ccggcatgtttggcctacatggagcgaaggctgcctagcggctcgccctacgctgctgca
cagcttttggaattcttcgattttcttcgtcatcgaacgcaaggcattgttccgacaaac
gcgaccttcttgcgagcctacctagctgctcaccccgactacaagcatgactctgtggta
tcccgaacgataagctttggcgtatgcgatttagctgcgaaaatagggcacgggactgtt
cgcattcctgagctctttgggccgtttgcacatcgcgtaggaatgcggatttcagatgac
gaaagcatccaggcgtacggagacttttcgaagcccctggtgacagctgatttcccctgt
ccactcggtggctttctcgcgtctgtgcgtgaacagcattgtgagaagggtcctgctgag
gcagaacctcactcgtccgtgagtgggatgaatcagaaaacaccagagaacctcttgtgc
aaccacagtgcgggtgcgtccttctcaccggaaaaatacggtctgtgcctttctaggcga
accaaaatggatcctccccaatccgaccctggactgagtttttaccttggaggccgtgtg
ccacttacattacagaaggcgtggaaaagccaacagattcagaggttttttgactttaga
aacgagaacagcatcagtaaaatggagatgagagagttcaggatccataaagacgtctgg
aatccagtccagcgcgaattccgtggctcgtctcatcgccctatcacgaccaataaggcg
gagtcgacatgggcatggatgctttccactgcagtaggagggccggacacggacactggc
gcttccgatgagaatgggtccacttcctgtccgagtttgggcgagatcggggatatttct
gacgaagcacaggcagagaaacgatataatggagcgagagaacaggaaggggcctgctct
cagggataa
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