Thermus sp. CCB_US3_UF1: TCCBUS3UF1_11200
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Entry
TCCBUS3UF1_11200 CDS
T01866
Name
(GenBank) Pyruvate dehydrogenase (Lipoamide)
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
thc
Thermus sp. CCB_US3_UF1
Pathway
thc00010
Glycolysis / Gluconeogenesis
thc00020
Citrate cycle (TCA cycle)
thc00620
Pyruvate metabolism
thc00785
Lipoic acid metabolism
thc01100
Metabolic pathways
thc01110
Biosynthesis of secondary metabolites
thc01120
Microbial metabolism in diverse environments
thc01200
Carbon metabolism
thc01210
2-Oxocarboxylic acid metabolism
Module
thc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
thc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
TCCBUS3UF1_11200
00020 Citrate cycle (TCA cycle)
TCCBUS3UF1_11200
00620 Pyruvate metabolism
TCCBUS3UF1_11200
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TCCBUS3UF1_11200
Enzymes [BR:
thc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
TCCBUS3UF1_11200
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
HTH_41
EAD5
Motif
Other DBs
NCBI-ProteinID:
AEV16164
UniProt:
G8ND23
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Position
1096896..1097936
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AA seq
346 aa
AA seq
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MKLKAVAYLSNGEFPVAEGEALALYRAMRRARFFDEKAMTLQRQGRLGVYAPFMGQEAAQ
VGLALALGEGDWVVPSYRESALLLARGLPIHTLLLYWRAHPAGWGFPEGVRAVNPYIPIA
TQIPQAVGLALAGRYRGEDWVVATSIGDGGTSEGDFHEGLNFAAVFSAPVVFLVQNNGYA
ISVPRSRQMRVDYIARRAEGYGMPGVVVDGNDALAVYLEAKRAVERARRGEGPTLLEALT
YRLAPHTTSDDPSRYRTREEEEAWRAKDPILRLRKALEERGLWDEGQEAALLEELEAEFA
RELSLADAAPEPRPEEIVEHVYAAMGPDQRRAWEALRRGQHVEEVW
NT seq
1041 nt
NT seq
+upstream
nt +downstream
nt
gtgaagctcaaagcggtggcgtacctgagtaacggggagtttcccgtggccgagggggag
gccctggccctgtaccgggccatgcgccgggcccggttttttgacgagaaggccatgacc
ctgcagcggcaggggcggcttggggtctatgcccccttcatgggccaggaggcggcccag
gtgggcctggccctggccctgggggagggggactgggtggtgcccagctaccgggaaagc
gccctcctgctggcccggggcctgcccatccacaccctcctcctctactggcgggcccac
cccgcgggctgggggtttcccgagggggtgcgggcggtaaatccctacatccccatcgcc
acccagatcccccaggccgtgggcctggccctggccgggcggtaccggggggaggactgg
gtggtggccacctccatcggggacggggggaccagcgagggggatttccatgaggggctg
aacttcgccgccgtcttctccgcccccgtggtcttcctggtgcagaacaacggctacgcc
atcagcgtcccccggtcccggcagatgcgggtggactacatcgcccgccgggccgagggc
tacggcatgcccggggtggtggtggacgggaacgatgccctggccgtctacctggaggct
aagagggcggtggaaagggcccggcggggggaggggcctaccctcctcgaggccctcacc
taccgcctagccccccacaccacctccgacgacccctcccggtaccgcacccgggaggag
gaggaggcctggcgggccaaggaccccatcctccgcctccgcaaggccctggaggagcgg
ggcctatgggacgaggggcaggaggcggcccttctggaggagctggaggcggagtttgcc
cgggagctttccctggccgacgccgcccccgagccgaggccggaggagatcgtggagcac
gtctacgccgccatgggccccgaccagcggcgggcctgggaagccctgaggcggggccaa
cacgtggaggaggtatggtag
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