Thermaerobacter sp. FW80: E1B22_04970
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Entry
E1B22_04970 CDS
T05930
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
thef
Thermaerobacter sp. FW80
Pathway
thef00790
Folate biosynthesis
thef01100
Metabolic pathways
thef01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
thef00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
E1B22_04970
Enzymes [BR:
thef01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
E1B22_04970
6.3.2.17 tetrahydrofolate synthase
E1B22_04970
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
AAA_16
Motif
Other DBs
NCBI-ProteinID:
QBS38481
UniProt:
A0A4P7GX09
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Position
1149261..1150628
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AA seq
455 aa
AA seq
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MRLGLQRIRRLLAALGHPEEDLPPVYHVTGTNGKGSTACILEAVLRAAGCRTALFTSPHL
VRYEERFAFDGRPVSGLELAAAIERVRSAADAVAATGEAPTEFEVATAVFFLLVQARRPD
AVVLEVGLGGRYDATNVVPRPAVSVVTNVALDHTDRLGRTVEEIAYDKVGIARPGVPLVT
GALDPAALRVLRRETARVGAPLWEVRPLTDAPPPAVGPGRDEPAGEPPGPVAVATYRLRT
TGPEGSRWDYRGPAGSPRGAAVRWDHLPLALVGPHQVANAAVAVAALQAAAATGRGLQVG
RAAVERGLAAARWPGRMERLRWQGRDVWLDGAHNPAGMAALARTVATLWPGRRVLLVIGM
LDDKDVEQAAGAIAPVTGRAVVSEPPSPRAAPAERLARALATQGVPVVVEREPVGALARA
LREAEPGQPVLVTGSLYLVGAVRAHVLAPAGTPGA
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgcggctgggactccagcggatccggcgcctgctggcggcgctgggccacccggaggag
gacctgccgcccgtctaccacgtgacggggaccaacggcaagggctctacggcgtgcatc
ctggaggccgtgctccgggcggcgggctgccggacggccctcttcacctccccgcacctg
gtccgctacgaggagcggttcgccttcgacggccggcccgtctccggccttgagctggcg
gccgccatcgagcgggtgcggagcgcagccgacgccgtggcggcgacgggcgaggcaccc
accgagttcgaggtggcgaccgccgtgttcttcctgctggtgcaggcgcgacggcccgac
gccgtcgtgctggaggtcggcctgggcgggcgctacgacgccaccaacgtggtgccccgg
ccggcggtctcggtggtcaccaacgtcgccctggatcacaccgaccggctgggccggacg
gtggaggagatcgcctacgacaaggtgggcatcgcgcgacccggcgtgcccctggtgacg
ggcgccctggaccccgcggccctgcgggtgctgcgccgggagacggcgcgggtgggcgcg
ccgctctgggaggtgcgtccgctgacggacgcaccccctcccgcggtggggccggggcgg
gacgaaccggccggcgagccacccgggccggtggcggtggccacctaccgcttgcggacc
accggtccggaggggtcgcgctgggactaccgggggccggccgggtcgccgcgcggcgca
gcggtgcgctgggaccacctgccgctggccctcgtcggcccccaccaggtcgccaatgcg
gcggtggccgtggccgcgctgcaggccgcggccgccaccggccgcggcctgcaggtgggc
cgcgcggcggtggagcgcggcctggccgccgcccgctggcccgggcgcatggagcgcctg
cgctggcagggccgggacgtctggctggacggcgcccacaatcccgccggcatggccgcc
ctggcccggacggtggccaccctctggcccggccgccgggtgctgctggtgatcggcatg
ctggacgacaaggacgtcgagcaggcggcgggtgccatcgccccggtgacgggacgggcc
gtggtgagcgagccgccgagcccgcgggccgcgccggcggagcgactggcgagggccttg
gcgacccagggcgtaccggtggtggtggagagggagccggtgggcgccctggcccgcgcg
ttgcgcgaggcggagcccgggcagccggtgctggtgaccggcagcctgtacctggtgggc
gccgtgcgggcccacgtgctggcgcccgcaggaacccccggcgcctga
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