Thermomonas aquatica: FHQ07_04585
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Entry
FHQ07_04585 CDS
T06025
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
thes
Thermomonas aquatica
Pathway
thes00790
Folate biosynthesis
thes01100
Metabolic pathways
thes01240
Biosynthesis of cofactors
Module
thes_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
thes00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
FHQ07_04585 (folC)
Enzymes [BR:
thes01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
FHQ07_04585 (folC)
6.3.2.17 tetrahydrofolate synthase
FHQ07_04585 (folC)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QDA56641
UniProt:
A0A5B7ZNB1
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All DBs
Position
complement(953014..954288)
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AA seq
424 aa
AA seq
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MNVMQRSISDWLDFIERQHPKAIDMGLDRVREVAARMGLKRPAKRVITVGGTNGKGSTVA
FVEAIARAHGWKVGSYTSPHLLRYNERVRIDGHDADDADLVAGFEAVEAARGDTPLTYFE
YGTLCALWLFARNKLDLAVLEVGLGGRLDAVNLVDADASIITTVDLDHQDWLGEDIETIG
LEKAGIARPFKPLVLGDDDPPASVLRHAYAIGAQAWRIANDFFAEPLDAGTWRWREVGFS
MQLPMPALAAPVQLRNAACAIAALRALGARIDKRTYAEGVANAQVAGRLQRFEQDGVEVV
VDVGHNPQAARALAAWLRRQPKRRTLAVYAALADKDVAGVVAALAEMVDGWHLAGLADAG
PRGQGVDDLARRLADTAAAGAVRHADVAAALDAAIAQADADGRVLVFGSFHTATAALERF
EANG
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgaacgtcatgcagcgatcaatttccgactggctcgatttcatcgaacgccagcacccg
aaagccatcgacatgggcctggaccgcgtgcgcgaagtcgccgcgcggatgggcttgaaa
cgtcccgccaagcgcgtgatcaccgtgggcggcaccaatggcaagggctcgaccgtcgcc
ttcgtcgaggccatcgcccgcgcgcatggctggaaggtcggcagctacacctcgccgcac
ctgctgcgctacaacgagcgcgtgcgcatcgatgggcacgatgccgatgatgcggatctc
gtcgccggtttcgaagcggttgaagcggcgcgcggcgacacgccgctgacctatttcgaa
tacggcacgctgtgcgcgctgtggctgttcgcgcgcaacaagctcgacctcgcggtgctg
gaagtcggcctcggcgggcggctggatgcggtgaacctggtcgatgcggatgcttcgatc
atcaccacggttgacctcgaccaccaggactggctgggcgaggacatcgaaaccatcggc
ctggagaaggccggcatcgcccgcccgttcaagccattggtgctgggcgacgacgatccg
ccggccagcgtgctgcgccatgcctatgcgatcggcgcgcaggcctggcggatcgccaac
gatttcttcgccgagcccctcgatgccggcacttggcgctggcgcgaggtcggtttctcg
atgcagttaccgatgcccgcgctcgccgcgccggtacagctgcgcaatgccgcctgcgcg
atcgccgccctgcgcgcgctgggtgcgcgcatcgacaagcgcacgtatgccgagggcgtg
gccaatgcgcaggtcgccgggcgcctgcaacgcttcgagcaggacggcgtggaggtggtg
gtcgatgtcggccacaacccgcaggcggcgcgtgcgttggcggcgtggctgcgtcgccaa
ccgaagcggcgcacgctggcggtgtatgccgcgctggcggacaaggacgttgcgggcgtg
gtggctgcgctggcggagatggtggatggctggcatctcgccggactggccgatgccggg
ccgcgcgggcagggcgtggacgacttggcgcggcgattggccgataccgcggccgctggc
gcggtccgccatgccgatgtcgcggcggcgctggatgccgccatcgcgcaggccgatgcg
gatggaagggtgctggtcttcggctccttccacaccgcgacggccgcgcttgagcgattc
gaggcgaacggttaa
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