Thermoflexus hugenholtzii: KNN16_00555
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Entry
KNN16_00555 CDS
T07254
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
thug
Thermoflexus hugenholtzii
Pathway
thug00010
Glycolysis / Gluconeogenesis
thug00020
Citrate cycle (TCA cycle)
thug00620
Pyruvate metabolism
thug00785
Lipoic acid metabolism
thug01100
Metabolic pathways
thug01110
Biosynthesis of secondary metabolites
thug01120
Microbial metabolism in diverse environments
thug01200
Carbon metabolism
thug01210
2-Oxocarboxylic acid metabolism
Module
thug_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
thug00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
KNN16_00555 (pdhA)
00020 Citrate cycle (TCA cycle)
KNN16_00555 (pdhA)
00620 Pyruvate metabolism
KNN16_00555 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
KNN16_00555 (pdhA)
Enzymes [BR:
thug01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
KNN16_00555 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
BEX
Motif
Other DBs
NCBI-ProteinID:
QWK10778
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Position
111840..112913
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AA seq
357 aa
AA seq
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MSGRGKGNAAKAAAPAAALDVATKLSFYRQMVLIRRFEELSRIAYQQGKIAGFLHLYIGE
EAVAVGAIAALRPEDHLITHYRDHGHAIARGLDPRVLMAELYGKVTGCSRGRGGSMHFAS
REHNFWGGHAIVGGHLPMAVGLGFAARYLGEPRVVMAIFGDAATDIGEFYEALNMAALWK
TPVVFLCENNLYGMGVAIEKASAVTEVYKKACMANIPAERIDGMDVLAVYEAATRAVEWA
RAGNGPYFLEALCYRFQGHSVADPELYRTKEEVEQWKQRDPIQRFRRHLIEVEGIPEARL
DAIHEEVEREMEEVMRFAEESPDPPLEEIYDFIYANPVGDWRGDERFLRLWDQSSGS
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
atgagcggtcgtgggaaagggaacgcagcgaaggctgcagcgccggccgcggcgcttgac
gtggcgaccaagctctccttctaccgccagatggtcctgatccgtcgctttgaggagctg
tctcgcatcgcgtatcagcaggggaagatcgccggcttcctgcacctctacatcggcgag
gaggctgtcgcagtgggcgccatcgccgccctccgcccggaggaccacctcatcacgcac
tatcgggatcacggccacgccatcgcccgggggctggatcctcgcgtcctgatggcggag
ctgtatgggaaggtcaccggctgcagccggggccgcgggggctccatgcacttcgccagc
cgggagcataacttctggggcgggcacgccatcgtgggcgggcacctgcccatggccgtg
ggcctgggcttcgccgcccgttatctgggggagccgcgcgtggtgatggctatcttcggc
gatgccgccacggacatcggggagttctacgaggccctgaacatggccgccctctggaag
acccccgtggtcttcctctgcgagaacaacctctatgggatgggcgtggccatcgagaag
gcctccgcggtcacggaggtctacaagaaggcctgcatggcgaacatccccgccgagcgg
atcgatggtatggatgtcctggccgtctacgaggcggcgacccgcgccgtggagtgggcc
cgcgccggcaacggcccctatttcctcgaggccctctgctaccgcttccagggccactcc
gtcgccgaccccgagctctatcgaactaaagaagaggtcgagcagtggaagcaacgggat
cccatccagcggttccgccggcacctcatcgaggtcgaggggatcccggaggcccggctg
gacgcgatccacgaagaggtggaacgcgagatggaggaggtgatgcgcttcgccgaggag
agcccggatccgcccctggaggagatctacgacttcatctacgccaacccggtgggggac
tggcggggcgatgagcgcttcctccggctctgggatcaatcctcaggatcctga
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