Thermotoga maritima MSB8: TM0166
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Entry
TM0166 CDS
T00022
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tma
Thermotoga maritima MSB8
Pathway
tma00790
Folate biosynthesis
tma01100
Metabolic pathways
tma01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
tma00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
TM0166
Enzymes [BR:
tma01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
TM0166
6.3.2.17 tetrahydrofolate synthase
TM0166
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Gene cluster
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AAD35259
UniProt:
Q9WY13
Structure
PDB
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All DBs
Position
complement(171412..172704)
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AA seq
430 aa
AA seq
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MAYLEVLRYLYHKRPMGKVKPGLERISMLLSKLGNPHLEYKTIHIGGTNGKGSVANMVSN
ILVSQGYRVGSYYSPHLSTFRERIRLNEEYISEEDVVKIYETMEPILNELDKEEIFSPSF
FEVVTAMAFLYFAEKNVDIAVLEVGLGGRLDATNVVFPLCSTIVTVDRDHEKTLGYTIEQ
IAWEKSGIIKERVPLVTGERKREALKVMEDVARKKSSRMYVIDKDFSVKVKSLKLHENRF
DYCGENTFEDLVLTMNGPHQIENAGVALKTLEATGLPLSEKAIREGLKNAKNLGRFEILE
KNGKMYILDGAHNPHGAESLVRSLKLYFNGEPLSLVIGILDDKNREDILRKYTGIFERVI
VTRVPSPRMKDMNSLVDMAKKFFKNVEVIEDPLEAIESTERATVVTGSLFLVGYVREFLT
TGKINEEWKL
NT seq
1293 nt
NT seq
+upstream
nt +downstream
nt
atggcatacctcgaagttctcaggtatctctaccacaaaagacctatgggaaaggtgaaa
ccaggtcttgagaggatctcaatgctactttcaaagctgggaaatccccatctggaatac
aaaaccatacacataggtggcacgaacggaaagggttctgttgcaaacatggtcagtaac
attctggtatctcaagggtacagagtgggatcatattactcccctcatctgagcacgttc
agagaaaggataaggttaaacgaagagtacatatccgaagaggacgtggtgaagatctac
gaaacaatggagccgattctgaacgagctcgacaaagaagaaatattctccccaagcttt
tttgaagttgtaacggcgatggcttttctctatttcgcggaaaaaaacgttgacattgcc
gtcctggaagttggtcttggaggcagactggacgcaacgaacgtggtgttccctctttgt
tccaccattgtcacggtggacagagatcacgaaaaaacgttgggatacaccatagaacag
atcgcatgggaaaaatccggaataataaaagaaagagttccccttgtgacaggggaaaga
aaaagagaagccctcaaagtgatggaagatgttgcccgaaagaagagctcaaggatgtac
gtcatcgacaaggatttttccgttaaggttaaatctctgaaacttcacgaaaacagattc
gattactgtggggaaaacaccttcgaagatctcgtcctgaccatgaacggtcctcaccag
atagaaaacgccggtgttgccctgaagactcttgaagcaacaggacttccgttgagcgag
aaagcaatacgcgaaggcttgaaaaatgcgaagaatctgggaagatttgaaatcttagag
aaaaacgggaagatgtacatcctcgatggagcgcacaaccctcacggagcggaaagcctt
gtcagaagcttgaaattgtacttcaacggcgaacccttgagcctggtaataggtattctg
gacgacaagaaccgggaggacattcttcgaaagtacaccggaatcttcgaaagggtcata
gtcacccgtgttccttcacctcgtatgaaagacatgaacagccttgttgacatggcaaag
aaattcttcaaaaacgtggaagtcatagaagatcccctggaagcgatcgaatctactgaa
agagccacggttgttacaggatcactgtttctagtgggatacgtaagggagttcctgaca
accggaaagataaatgaggagtggaaactatga
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