Treponema medium: DWB79_11595
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Entry
DWB79_11595 CDS
T07695
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tmed
Treponema medium
Pathway
tmed00790
Folate biosynthesis
tmed01100
Metabolic pathways
tmed01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
tmed00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
DWB79_11595
Enzymes [BR:
tmed01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
DWB79_11595
6.3.2.17 tetrahydrofolate synthase
DWB79_11595
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Motif
Pfam:
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QSH98377
UniProt:
A0A898DH36
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Position
2609276..2610811
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AA seq
511 aa
AA seq
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MNEAYNTDSIPIAHQENLNDFYRWLDGFINFEKRPHKKNFSLEVIRYYATLFSNPQTTYK
CIHIAGSKGKGSVAVMLSALLTETGYKTGLYTSPHVNDFRERITENGRFFSDLAYLEAFR
AVQESVMPHIDKETEPQPSWFELVTLTAFVLFRQERLDWAVFETGMGGRLDATNIIQPEI
TILTPIELEHCEYLGHTIPLIAAEKAGIIKAGVPVFCSRQQPSALEVFKERAAALNAPFF
YLPDFIETIEHRLTPQGREVTICFSADHPVGALFKRPLHAILPLFTPVQAENAALAAAAF
KYRFPDMPEDLIESGLSKAWLPARFQLLSTKPLIVLDGAHTHNSIQTCADTFFSLLSDGS
GASIPYNDSTSVHSGTPPVSGTISAYSDTQSIPDAPPNAKPILVFACAADKDPAGFAPIF
YGNIAHLYLTVPGSFKKGNLEKTVIAFTQVFENENSVVMEASEDFNAVLKKAFTQSITEN
RPLLITGSFYLAAEAQRVYSAEGFQDRETQG
NT seq
1536 nt
NT seq
+upstream
nt +downstream
nt
atgaacgaagcatataataccgattcaatacccatagctcatcaagaaaatctgaacgat
ttttaccgatggcttgacggttttattaactttgaaaaacgaccgcataaaaaaaacttt
tcgcttgaggttatcagatactatgcaacgctcttttccaacccgcaaacaacgtataaa
tgcatacacattgccggttcaaagggaaagggttccgttgcggtgatgctttcagcctta
ctcaccgaaaccggttataagaccggcctctacacctctccacatgtaaacgacttccgc
gagcggataacggaaaacggtcgttttttcagtgatttagcctaccttgaagcattccgt
gccgtacaggagagcgttatgccgcatatcgataaagagacggaaccccaaccgagctgg
ttcgagctggtaacacttacggcctttgtactgttccggcaagagcggctcgactgggcg
gtgtttgaaaccggcatggggggcaggcttgacgctaccaatatcatacagccggaaata
accatactgacaccgatcgagcttgaacactgtgaatatctcggtcataccattccgctc
attgcggcagaaaaagcgggaatcattaaagcgggtgttcccgttttttgctcacgtcaa
caaccttccgcgcttgaagtattcaaagaacgggcggcggcactcaatgctccgtttttt
tatctacccgattttatcgaaacgattgaacaccggctgacaccgcaaggccgcgaagtt
accatctgcttttcagctgaccatccggtaggagcgctctttaaacgtccgctgcacgca
atactcccgctttttacgcccgtacaggcggagaacgctgcgctcgccgccgccgctttt
aaataccgctttcccgatatgccggaagacttaatcgaaagcgggctttcaaaggcatgg
ctccccgcgcgcttccagcttttaagtacgaagccgctgattgtcctcgacggcgcacat
acgcataacagcatccaaacctgtgcagacacgtttttttctctcctcagcgatggatcc
ggcgcttcgattccctataacgacagtacatccgtacattccggtactccgcccgtctcc
ggtactatatccgcatactctgatactcagtccatacccgatgcgccaccgaacgccaag
ccgatactggtgtttgcctgcgcggccgataaagaccccgccggttttgcgccgatattc
tacggcaacattgcgcacctctacctcaccgtgccgggctcgtttaaaaagggcaattta
gaaaaaaccgtcatcgcatttacgcaggttttcgaaaatgagaacagtgttgtaatggaa
gcaagtgaagattttaacgcagtattaaagaaggcctttacccaaagcattaccgaaaat
cggccgctgttgattacgggttcattctatctggcggcggaagcgcaacgagtatattcc
gctgagggttttcaggatcgggaaactcaaggctga
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