KEGG   Trichechus manatus latirostris (Florida manatee): 101342555
Entry
101342555         CDS       T05135                                 
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
tmu  Trichechus manatus latirostris (Florida manatee)
Pathway
tmu01521  EGFR tyrosine kinase inhibitor resistance
tmu01522  Endocrine resistance
tmu04012  ErbB signaling pathway
tmu04015  Rap1 signaling pathway
tmu04062  Chemokine signaling pathway
tmu04137  Mitophagy - animal
tmu04144  Endocytosis
tmu04360  Axon guidance
tmu04370  VEGF signaling pathway
tmu04510  Focal adhesion
tmu04520  Adherens junction
tmu04530  Tight junction
tmu04540  Gap junction
tmu04611  Platelet activation
tmu04613  Neutrophil extracellular trap formation
tmu04625  C-type lectin receptor signaling pathway
tmu04727  GABAergic synapse
tmu04750  Inflammatory mediator regulation of TRP channels
tmu04810  Regulation of actin cytoskeleton
tmu04912  GnRH signaling pathway
tmu04915  Estrogen signaling pathway
tmu04917  Prolactin signaling pathway
tmu04919  Thyroid hormone signaling pathway
tmu04921  Oxytocin signaling pathway
tmu04926  Relaxin signaling pathway
tmu05100  Bacterial invasion of epithelial cells
tmu05135  Yersinia infection
tmu05152  Tuberculosis
tmu05161  Hepatitis B
tmu05163  Human cytomegalovirus infection
tmu05167  Kaposi sarcoma-associated herpesvirus infection
tmu05168  Herpes simplex virus 1 infection
tmu05203  Viral carcinogenesis
tmu05205  Proteoglycans in cancer
tmu05207  Chemical carcinogenesis - receptor activation
tmu05208  Chemical carcinogenesis - reactive oxygen species
tmu05219  Bladder cancer
tmu05417  Lipid and atherosclerosis
tmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    101342555
   04015 Rap1 signaling pathway
    101342555
   04370 VEGF signaling pathway
    101342555
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101342555
   04137 Mitophagy - animal
    101342555
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101342555
   04520 Adherens junction
    101342555
   04530 Tight junction
    101342555
   04540 Gap junction
    101342555
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101342555
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101342555
   04613 Neutrophil extracellular trap formation
    101342555
   04625 C-type lectin receptor signaling pathway
    101342555
   04062 Chemokine signaling pathway
    101342555
  09152 Endocrine system
   04912 GnRH signaling pathway
    101342555
   04915 Estrogen signaling pathway
    101342555
   04917 Prolactin signaling pathway
    101342555
   04921 Oxytocin signaling pathway
    101342555
   04926 Relaxin signaling pathway
    101342555
   04919 Thyroid hormone signaling pathway
    101342555
  09156 Nervous system
   04727 GABAergic synapse
    101342555
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101342555
  09158 Development and regeneration
   04360 Axon guidance
    101342555
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101342555
   05207 Chemical carcinogenesis - receptor activation
    101342555
   05208 Chemical carcinogenesis - reactive oxygen species
    101342555
   05203 Viral carcinogenesis
    101342555
  09162 Cancer: specific types
   05219 Bladder cancer
    101342555
  09172 Infectious disease: viral
   05161 Hepatitis B
    101342555
   05168 Herpes simplex virus 1 infection
    101342555
   05163 Human cytomegalovirus infection
    101342555
   05167 Kaposi sarcoma-associated herpesvirus infection
    101342555
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101342555
   05152 Tuberculosis
    101342555
   05100 Bacterial invasion of epithelial cells
    101342555
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101342555
   05418 Fluid shear stress and atherosclerosis
    101342555
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101342555
   01522 Endocrine resistance
    101342555
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tmu01001]
    101342555
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tmu04131]
    101342555
Enzymes [BR:tmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     101342555
Protein kinases [BR:tmu01001]
 Non-receptor tyrosine kinases
  SRC family
   101342555
Membrane trafficking [BR:tmu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    101342555
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    101342555
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    101342555
  Macropinocytosis
   Kinases
    101342555
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 101342555
NCBI-ProteinID: XP_012414264
UniProt: A0A2Y9G0M3
LinkDB
Position
Unknown
AA seq 542 aa
MGSNKSKPKDASQRRRSLEPTENTHSGGGGAFPASQTPSKPASADGHRGPNTAFVPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNTENPRGT
FLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYS
KHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR
VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLK
GETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI
EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREV
LDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE
NL
NT seq 1629 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccagcggcgccgcagcctggagccc
accgagaacacccacagtggcggcgggggagccttccctgcctcacagacccccagcaag
ccggcctccgctgatggccaccgtggccccaacacggcctttgtcccggcagccgctgag
cccaagctgtttggaggcttcaactcctcggacacggtcacttccccgcagagggcgggg
ccgctggctggaggagtgaccacctttgtggccctctatgactatgagtctaggacagag
actgacctgtccttcaagaagggggagcggctccagattgtcaacaacacgaggaaggtg
gatgtcagagagggagactggtggctggcccactcgctcagcacaggacagacgggctac
atccccagcaactacgtggcaccctccgactccatccaggctgaggagtggtacttcggc
aagatcaccagacgggagtcagaaaggctgttgctcaatacggaaaacccacgagggacc
ttcctggtgcgagaaagtgagaccacgaaaggcgcctactgcctctcagtgtccgacttc
gacaatgccaagggcctcaatgtgaagcactacaaaatccgcaagctggacagcggtggc
ttctacatcacctcccgcacccagttcaatagtctgcagcagctcgtggcctactactcc
aaacacgctgatggcctgtgccaccgtctcaccaccgtgtgccccacgtccaagccgcag
actcagggcctggccaaggacgcctgggagatcccccgggagtctctgcggctggaggtc
aagctgggccagggctgcttcggagaggtgtggatggggacctggaatggcaccaccagg
gtggccatcaaaaccctgaagccgggcacgatgtcgccagaggccttcctgcaggaggcc
caggtcatgaagaaactgaggcacgagaagctggtgcagctgtacgcggtggtgtccgag
gaacctatctacattgtcaccgagtacatgagcaaggggagtttgctggactttctcaag
ggggaaacgggcaagtacctgcggctccctcagctagtggacatggctgctcagatcgcc
tcaggcatggcgtacgtggagaggatgaactatgtccaccgggacctccgtgctgccaat
atcctggttggagagaacctggtatgcaaagtggctgacttcgggctggctcgactcatc
gaagacaatgagtacaccgcccggcaaggtgccaaattccccatcaagtggacggctcca
gaagctgccctgtacggccggttcaccatcaagtcggacgtatggtcctttgggatcctg
ctgacggagctcaccacgaagggacgggtgccctaccctgggatggtgaaccgagaggtg
ctggaccaggtagagcggggctaccggatgccctgcccgcccgagtgccctgagtccctg
catgacctcatgtgtcagtgctggcggaaggagccggaggagcggcccaccttcgagtac
ctgcaggccttcctggaggactacttcacatccaccgagccccagtaccagcccggcgag
aacctatag

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