Thermotoga neapolitana: CTN_0521
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Entry
CTN_0521 CDS
T00847
Name
(GenBank) Folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tna
Thermotoga neapolitana
Pathway
tna00790
Folate biosynthesis
tna01100
Metabolic pathways
tna01240
Biosynthesis of cofactors
Module
tna_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
tna00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CTN_0521
Enzymes [BR:
tna01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CTN_0521
6.3.2.17 tetrahydrofolate synthase
CTN_0521
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ACM22697
UniProt:
B9K6W4
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Position
523757..525052
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AA seq
431 aa
AA seq
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MGYLDILRYLYHKRPMSKIKPGLERISLLLSLLGNPHTKYRVIHVGGTNGKGSVTNMISN
VLIAQGYRVGSYYSPHLSTFRERIRLNEEFISEEDVERIYQQMEPVLKRLDENEVFSPSF
FETVTAMAFLYFAEKNVDVAVVEVGLGGRLDATNVVSPLCSIIVTVDRDHEKVLGTTIEQ
IAWEKSGIIKNSVPVVTGEEKTEALKVIEEVARKKGSKVYALNRDFAVEVESLKLFENRF
SYLGDKVLKDLVLTMNGPHQLTNAGVALKALEAIDLSVSESAIREGLKKAKNLGRFEVIE
KDGKRFILDGAHNPHGARSLVKSLKLYFKEPLNLIIGVLDDKDRAGILKEYRNVFDRIVL
TRVPSPRMKDFDGFVALAKEILGNVDVIEDPLEALKIAEEKSVTVVSGSLFLVGYVREYL
ETGKIGEEWYL
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgggatacctggacattttgagatatctctaccacaagcgccctatgagtaagataaaa
ccgggtcttgagaggatctctctgcttctttcccttcttggaaatccccacacgaagtac
cgggtcattcatgttggaggaacaaatggcaaaggttccgtcacgaacatgatcagcaac
gttctcatagcacaggggtacagggtgggttcgtattactcaccacatctcagcaccttc
agagagaggatcaggttgaacgaagagttcatctccgaggaagatgtagaaaggatctat
cagcaaatggaacccgttttgaaacgtctggatgagaacgaagtgttttctcccagtttc
ttcgagacggtcacggcgatggcctttctctattttgcagagaaaaatgttgatgtggcc
gttgtggaggtagggcttggaggacgtctggacgccacaaacgtcgtatccccactctgc
tcgatcatcgtaacggtggatagggatcacgagaaagtgctgggtacaaccatcgaacag
atcgcctgggaaaaatccgggataataaaaaactctgttccagttgtcaccggagaagaa
aagacagaagcactgaaagtgatagaagaggtggcgagaaagaaaggatcgaaagtgtac
gctctcaacagagatttcgccgtggaggttgaatcgttgaaactcttcgaaaacaggttc
agctacctgggagacaaagtgttgaaagaccttgttttgacgatgaacggacctcatcag
ttgacaaacgcgggggttgctttgaaagcgctggaagcgatcgatctttcggtgagcgag
tcggcgatccgggaaggcttgaaaaaggcgaaaaatcttggaagattcgaagtgattgaa
aaggacggaaaaagattcattctggatggagctcacaatccccacggtgcgaggtctctt
gtgaaatcgctgaaactgtatttcaaagaacctttgaatctgatcatcggtgtgctggac
gacaaagatcgagctggcattttgaaggaatacaggaacgttttcgatagaatcgtcctc
acacgggttccttcccccagaatgaaagatttcgatgggtttgttgcacttgcaaaggag
atactgggaaacgtcgatgtcatagaagatcccctcgaagcgctgaagatcgccgaggaa
aaatcagtaactgtcgtcagcgggtctctctttcttgtgggttacgtcagagagtacctc
gagacaggaaagatcggtgaggagtggtacctgtga
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