Talpa occidentalis (Iberian mole): 119234535 Help Entry 119234535         CDS       T07495                                  Symbol HK1 Name (RefSeq) hexokinase-1 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism tod  Talpa occidentalis (Iberian mole) Pathway tod00010   Glycolysis / Gluconeogenesis tod00051   Fructose and mannose metabolism tod00052   Galactose metabolism tod00500   Starch and sucrose metabolism tod00520   Amino sugar and nucleotide sugar metabolism tod00524   Neomycin, kanamycin and gentamicin biosynthesis tod01100   Metabolic pathways tod01200   Carbon metabolism tod01250   Biosynthesis of nucleotide sugars tod04066   HIF-1 signaling pathway tod04910   Insulin signaling pathway tod04930   Type II diabetes mellitus tod04973   Carbohydrate digestion and absorption tod05230   Central carbon metabolism in cancer Module tod_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate tod_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose tod_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:tod00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     119234535 (HK1)    00051 Fructose and mannose metabolism     119234535 (HK1)    00052 Galactose metabolism     119234535 (HK1)    00500 Starch and sucrose metabolism     119234535 (HK1)    00520 Amino sugar and nucleotide sugar metabolism     119234535 (HK1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     119234535 (HK1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     119234535 (HK1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     119234535 (HK1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     119234535 (HK1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     119234535 (HK1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     119234535 (HK1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:tod04131]     119234535 (HK1) Enzymes [BR:tod01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      119234535 (HK1) Membrane trafficking [BR:tod04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     119234535 (HK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 UvrD-helicase Motif Other DBs NCBI-GeneID:  119234535 NCBI-ProteinID:  XP_037353420 LinkDB All DBs Position Unknown AA seq 921 aa AA seqDB search MGQNCHRGVDLSSKNVIHPPLDQNKIDKYLYAMRLSDETLLDIMARFKKEMKNGLSRDYN PTAAVKMLPTFVRSIPDGSEKGDFIALDLGGSFFRILRVQVNHEQSQNVFMESEIYPTPE SIVHGSGSQLFDHVAECLGDFMEKKRIKDKNLPVGFTFSFPCRQSKIDEAILITWTKRFK ASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDHQCEVGLIIGTGTNA CYMEELRHIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDREIDRGSLNPGKQLFEKM VSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEIL TRLGVEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILSRLRDNKGTARLRTTVGVDGSL YKTHPQYSRRFHKTLRRLVPDSDVRFLVSESGSGKGAAMVTAVAYRLAEQHRQIEETLAH FRLTKDMLLEVKKRMRAEMEMGLNKKTHDNAVVKMLPSFVRSTPDGTEHGDFLALDLGGT NFRVLLVKVRSGKKRTVEMHNKIYAIPTEIMQGTGEELFDHIVSCISDFLDYMGIKGPKM PLGFTFSFPCKQTNLDEGILITWTKGFKATDCVGHDVATLLRDAVKRREEFEVDVVAVVN DTVGTMMTCAYEEPSCEVGLIVGTGSNACYMEEMKNIQMLDGDEGRMCINMEWGAFGDNG SLDDIRTTYDRMVDEHSLNAGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISESL KTWGIFQTKYLSQIESDRLALLQVRAILQQLGLDSTCDDSILVKTVCGVVSRRAAQLCGA GMAAVVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVSELSPKCNVSFLLSEDG SGKGAALITAVGVRLREERSS NT seq 2766 nt NT seq  +upstreamnt  +downstreamnt atgggacagaactgccatcgaggagtggatttatcctctaaaaatgtaatccatccccct cttgatcaaaataagattgacaagtatctctatgccatgcggctctctgatgagactctg ttagatatcatggctcgtttcaagaaggagatgaagaatggcctctcccgggattataat cccacagctgcagtcaagatgttgccaacgtttgtaaggtccattcctgatggttcagaa aagggagatttcatcgccctggaccttggtgggtctttctttcgaattctgcgagtgcaa gtgaatcatgagcaaagccagaatgtttttatggagtctgagatttatcccacgccggag agcatcgtgcatggcagtggaagccagctttttgatcatgttgctgagtgcctgggagac ttcatggagaagaagaggatcaaggacaagaacttacctgtgggattcacattctctttc ccttgtcggcagtccaaaatagacgaggccatcctgatcacctggacaaagagatttaaa gcgagtggagtggaaggagcagatgtggtgaagctgcttaacaaagccatcaagaagcga ggggactatgatgccaacattgtggctgtggtgaatgacaccgtggggaccatgatgacc tgtggctatgatgaccatcagtgtgaagttggactcatcattggcactggcaccaatgcc tgttacatggaggagctgaggcacatcgacctggtggaaggtgacgaggggaggatgtgc atcaacacggagtggggggcctttggggacgatggggccctggaagacatccgcaccgag tttgaccgggagattgaccgcgggtccctcaaccccgggaaacagctgtttgagaagatg gtcagtggcatgtacctgggggagctggttcgcctgatcctggtcaagatggccaaggag ggcctcttatttgaagggcggatcaccccagagctgctcaccagagggaagtttaatacc agtgatgtgtcagctattgaaaagaataaggaaggcctccacaacgccaaagaaatcctg acccgcctaggagtggagccgtccgatgacgactgtgtttccgttcagcacgtgtgcacc atcgtctcctttcgctctgccaacctggtggctgcaacgctgggtgccatcttgagccgc cttcgagataacaagggcacagccaggctgcggaccacggttggtgtcgacgggtctctt tacaagacgcacccacagtattcccggcgtttccacaagactctgaggcgcttggtgccc gactccgacgtgcgtttcctcgtctcagagagtggcagtggcaagggggccgccatggtg accgcggtggcctaccgtctggctgagcagcaccggcagatagaggagaccctggctcac ttccgcctcaccaaggacatgctgctggaggtgaagaagaggatgcgggccgagatggag atggggctgaataagaagacgcatgataacgccgtagtcaagatgctgccctcctttgtt cggagcactccggatggaacagagcacggtgacttcttggctctggatctcggaggaacg aatttccgcgtcttgctggtgaaagtccgtagtgggaaaaagagaactgtagaaatgcac aacaagatctatgccattcccactgaaatcatgcagggcaccggggaagagctgtttgac cacattgtctcttgcatctccgacttcctggactacatggggatcaaaggccccaaaatg cctttgggcttcaccttctcattcccctgcaaacagacgaacttggatgagggtatcttg ataacctggacaaagggttttaaggctactgactgtgtgggccatgatgtggcaacctta ctaagggatgcggtaaaaaggagagaggaatttgaagtggacgtggtggctgtggtcaat gacaccgtgggcaccatgatgacctgtgcttatgaggagcccagctgtgaggttggactc atcgtaggcaccggctccaacgcctgctacatggaagaaatgaagaacatccagatgctg gatggggatgaggggcgaatgtgtatcaacatggagtggggtgcctttggggacaatggg agcctggatgatatcagaacaacctatgacaggatggtggatgagcattctctaaatgct gggaaacaaaggtttgagaagatgatcagtggtatgtacctcggtgaaattgtccgcaac atcttgattgacttcaccaagaaggggttcctcttccgggggcagatctctgagtcgctg aagacctggggcatcttccagaccaagtatctctctcagattgagagtgaccggttagcg ctgctgcaggtccgggccatccttcagcagctgggcctggacagcacctgcgacgacagt atcctcgtgaagacagtgtgcggagtggtgtccaggagggcggcacagctgtgtggcgct ggcatggctgccgtggtggataagatacgagagaacagaggcctagaccatctcaacgtg actgtgggggtagacggaacactttacaagctgcatccacacttctcccgaatcatgcac caaaccgtgtcggaactgtcaccaaagtgtaacgtgtccttcctcctgtccgaggacggc agcggcaagggtgcggcccttatcacggcagtgggcgtccggctccgagaagagaggagc agctaa

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