Talpa occidentalis (Iberian mole): 119246292
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Entry
119246292 CDS
T07495
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00010
Glycolysis / Gluconeogenesis
tod00020
Citrate cycle (TCA cycle)
tod00620
Pyruvate metabolism
tod00785
Lipoic acid metabolism
tod01100
Metabolic pathways
tod01200
Carbon metabolism
tod01210
2-Oxocarboxylic acid metabolism
tod04066
HIF-1 signaling pathway
tod04922
Glucagon signaling pathway
tod05230
Central carbon metabolism in cancer
tod05415
Diabetic cardiomyopathy
Module
tod_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
119246292 (PDHA1)
00020 Citrate cycle (TCA cycle)
119246292 (PDHA1)
00620 Pyruvate metabolism
119246292 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
119246292 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
119246292 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
119246292 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
119246292 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
119246292 (PDHA1)
Enzymes [BR:
tod01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
119246292 (PDHA1)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
119246292
NCBI-ProteinID:
XP_037368534
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDVLCVREATKFAAAHCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNNNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgcggtgtcgcgcgtgttatcgggcgccgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaag
tgtgatcttcaccggctggaagagggccctcccgtcacaactgtgctcaccagggaggat
ggactcagatactacaggatgatgcagaccgtgcgccgaatggagttaaaggctgaccag
ctgtacaagcagaaaatcattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaagctggtataaaccccacggaccatcttatcacagcctatcgggct
catggcttcacctttactcgtgggctttctgtccgagaaattcttgcagagcttacagga
cgaagaggaggctgtgctaaaggaaagggaggctcgatgcatatgtatgcgaagaacttc
tacggtggcaatggcatcgttggagcccaggtgcccctgggagctgggattgctctggcc
tgtaagtataacggaaaagatgaggtctgtttgactttatatggcgatggtgctgctaat
cagggtcagatatttgaagcttacaatatggcagctttgtggaaattgccttgcattttc
atctgtgaaaataaccgctatggaatgggaacctctgttgagagagcagccgccagcact
gactactacaagagaggcgacttcatccccgggctgagggtagacggaatggatgtcctg
tgtgtccgggaggcgacaaagtttgcagctgcccattgtagatccggaaaagggcccata
ctgatggagttacagacttaccgttaccatggacacagcatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctatcatgcttctc
aaggacagaatggtgaacaacaatcttgcgagcgtggaggaattaaaggaaattgatgtg
gaagtgaggaaagaaattgaggatgctgcccagtttgccaccgctgatcctgaaccacct
ttggaagaactaggctatcacatctatagcagcgacccaccttttgaagttcgtggtgca
aatcagtggatcaagtttaagtccatcagttaa
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integrated database retrieval system
