KEGG   Talpa occidentalis (Iberian mole): 119247369
Entry
119247369         CDS       T07495                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod01521  EGFR tyrosine kinase inhibitor resistance
tod01522  Endocrine resistance
tod04010  MAPK signaling pathway
tod04014  Ras signaling pathway
tod04015  Rap1 signaling pathway
tod04066  HIF-1 signaling pathway
tod04068  FoxO signaling pathway
tod04114  Oocyte meiosis
tod04115  p53 signaling pathway
tod04150  mTOR signaling pathway
tod04151  PI3K-Akt signaling pathway
tod04152  AMPK signaling pathway
tod04211  Longevity regulating pathway
tod04213  Longevity regulating pathway - multiple species
tod04510  Focal adhesion
tod04550  Signaling pathways regulating pluripotency of stem cells
tod04730  Long-term depression
tod04750  Inflammatory mediator regulation of TRP channels
tod04913  Ovarian steroidogenesis
tod04914  Progesterone-mediated oocyte maturation
tod04935  Growth hormone synthesis, secretion and action
tod04960  Aldosterone-regulated sodium reabsorption
tod05200  Pathways in cancer
tod05202  Transcriptional misregulation in cancer
tod05205  Proteoglycans in cancer
tod05214  Glioma
tod05215  Prostate cancer
tod05218  Melanoma
tod05224  Breast cancer
tod05410  Hypertrophic cardiomyopathy
tod05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119247369 (IGF1)
   04014 Ras signaling pathway
    119247369 (IGF1)
   04015 Rap1 signaling pathway
    119247369 (IGF1)
   04066 HIF-1 signaling pathway
    119247369 (IGF1)
   04068 FoxO signaling pathway
    119247369 (IGF1)
   04151 PI3K-Akt signaling pathway
    119247369 (IGF1)
   04152 AMPK signaling pathway
    119247369 (IGF1)
   04150 mTOR signaling pathway
    119247369 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    119247369 (IGF1)
   04115 p53 signaling pathway
    119247369 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    119247369 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    119247369 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    119247369 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    119247369 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    119247369 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    119247369 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    119247369 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    119247369 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    119247369 (IGF1)
   04213 Longevity regulating pathway - multiple species
    119247369 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119247369 (IGF1)
   05202 Transcriptional misregulation in cancer
    119247369 (IGF1)
   05205 Proteoglycans in cancer
    119247369 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    119247369 (IGF1)
   05218 Melanoma
    119247369 (IGF1)
   05215 Prostate cancer
    119247369 (IGF1)
   05224 Breast cancer
    119247369 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    119247369 (IGF1)
   05414 Dilated cardiomyopathy
    119247369 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    119247369 (IGF1)
   01522 Endocrine resistance
    119247369 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:tod04052]
    119247369 (IGF1)
Cytokines and neuropeptides [BR:tod04052]
 Cytokines
  Growth factors (RTK binding)
   119247369 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 119247369
NCBI-ProteinID: XP_037369660
LinkDB
Position
Unknown
AA seq 159 aa
MGKISSLPTQLFKCCFCDFLKVKMHSVSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRTPQTGIVDECCFRSCDLRRLEMYCAPLKPAKAARS
VRAQRHTDMPKAQKYQPPSTNKKTKSQRRRKGSAFEERK
NT seq 480 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtcaagatgcacagcgtgtcctcctcacacctcttctacctggccctgtgcttgctc
accttcaccagctccgccacggctggaccggagacactctgcggggctgagctggtggac
gctcttcagttcgtgtgtggagacaggggcttttatttcaacaagcccacggggtacggg
tccagcagtcggaggacgccccagacaggcatcgtggatgagtgctgcttccggagctgt
gacctgagaaggctggagatgtactgcgcacccctcaaacctgccaaggcggcccgctcc
gtccgtgcccagcgtcacaccgacatgcccaaggctcagaagtatcagcccccatccacc
aacaagaaaacgaagtctcagaggagaaggaaaggaagtgcatttgaagaacgcaagtag

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