Talpa occidentalis (Iberian mole): 119249351
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Entry
119249351 CDS
T07495
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X2
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00280
Valine, leucine and isoleucine degradation
tod00640
Propanoate metabolism
tod00785
Lipoic acid metabolism
tod01100
Metabolic pathways
tod01210
2-Oxocarboxylic acid metabolism
Module
tod_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
119249351 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
119249351 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
119249351 (BCKDHA)
Enzymes [BR:
tod01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
119249351 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
119249351
NCBI-ProteinID:
XP_037372528
LinkDB
All DBs
Position
Unknown
AA seq
479 aa
AA seq
DB search
MAVAAAAARVGGLRRVLSQAGFLFLRRPGARGLARSLLADVLVVQGEEEEGNFNCQGSPR
WFLNHHPKKQHPQRQQQHFSSLDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQG
QIINPSEDPQLPQEKVLKFYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAA
AMDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNVNDMGKGRQMPVHYGCKERHFVTIS
SPLATQIPQAVGAAYAAKRANDNRAVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRN
NGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLI
EAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLQSRGWWDDEQEKAWRKQS
RKKVMEAFEQAERKPKPNPSLLFSDVYQEMPAQLRKQQESLARHLQTYGEHYPLEHFDK
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggcagctgcagcggcgagggtcggggggctgcgtcgagtcctgagccaggct
ggcttcctgttcctgcggcggcccggagcgcgggggttggctagatctttgctagcagat
gttttagtggttcagggagaagaggaggaaggaaacttcaattgtcaagggagtcctcgc
tggtttctcaaccaccaccccaaaaagcagcacccccagaggcagcaacagcacttctca
tccctggatgacaagccccagtttccaggggcctcggcggaatttattgacaagctagag
ttcatccagcccaatgtcatctctggaatccccatctaccgcgtcatggaccggcagggc
cagatcatcaaccccagcgaggatccccaactgccccaggagaaggtgctcaagttctac
aaaagcatgaccctgctcaacaccatggaccgcatcctctatgagtcccagcggcagggc
cggatctccttctacatgaccaactatggtgaggaggggacgcacgtggggagtgctgcg
gccatggacaacacggacctggtgtttggccagtaccgggaggcaggtgtgctgatgtac
cgggactaccccctggagctcttcatggcccagtgctacggcaacgtgaacgacatgggc
aaggggcgccaaatgccggtccactatggctgcaaggagcgccacttcgtcaccatctcc
tctcccctggccacgcagatccctcaggctgtgggggcggcctacgcagccaagagggcc
aatgacaacagggccgtcatctgttacttcggcgagggggcggccagtgagggggatgct
cacgccggcttcaatttcgccgccaccctggagtgccccatcatcttcttctgccggaac
aatggctatgccatctccacacccacctctgagcagtaccgcggggatggcatagcggct
cgaggccctggctatggcatcatgtcgatccgcgtggatggcaacgacgtgtttgctgtg
tacaatgccaccaaagaggcccggcgacgggctgtggccgagaaccagccctttctcatt
gaggccatgacctacaggatcgggcaccacagcaccagtgacgacagctctgcataccgc
tcggtggatgaggtcaactactgggacaagcaggaccaccccatctcccggctgaggcac
tacctgcagagccgtggctggtgggacgatgaacaggagaaggcctggaggaagcagtcc
cgcaagaaggtgatggaggcctttgagcaggctgagcggaagccgaagcccaaccccagc
ctgctgttctcagacgtgtaccaggagatgcccgcccagctccgcaagcagcaggagtcc
ctggcccgtcatcttcagacctatggcgagcactaccccctggagcactttgacaagtga
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