Talpa occidentalis (Iberian mole): 119257456 Help Entry 119257456         CDS       T07495                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism tod  Talpa occidentalis (Iberian mole) Pathway tod00230   Purine metabolism tod01100   Metabolic pathways tod01522   Endocrine resistance tod04015   Rap1 signaling pathway tod04022   cGMP-PKG signaling pathway tod04024   cAMP signaling pathway tod04062   Chemokine signaling pathway tod04072   Phospholipase D signaling pathway tod04114   Oocyte meiosis tod04211   Longevity regulating pathway tod04213   Longevity regulating pathway - multiple species tod04261   Adrenergic signaling in cardiomyocytes tod04270   Vascular smooth muscle contraction tod04371   Apelin signaling pathway tod04540   Gap junction tod04611   Platelet activation tod04713   Circadian entrainment tod04714   Thermogenesis tod04723   Retrograde endocannabinoid signaling tod04724   Glutamatergic synapse tod04725   Cholinergic synapse tod04726   Serotonergic synapse tod04727   GABAergic synapse tod04728   Dopaminergic synapse tod04750   Inflammatory mediator regulation of TRP channels tod04911   Insulin secretion tod04912   GnRH signaling pathway tod04913   Ovarian steroidogenesis tod04914   Progesterone-mediated oocyte maturation tod04915   Estrogen signaling pathway tod04916   Melanogenesis tod04918   Thyroid hormone synthesis tod04921   Oxytocin signaling pathway tod04923   Regulation of lipolysis in adipocytes tod04924   Renin secretion tod04925   Aldosterone synthesis and secretion tod04926   Relaxin signaling pathway tod04927   Cortisol synthesis and secretion tod04928   Parathyroid hormone synthesis, secretion and action tod04934   Cushing syndrome tod04935   Growth hormone synthesis, secretion and action tod04970   Salivary secretion tod04971   Gastric acid secretion tod04972   Pancreatic secretion tod04976   Bile secretion tod05012   Parkinson disease tod05030   Cocaine addiction tod05031   Amphetamine addiction tod05032   Morphine addiction tod05034   Alcoholism tod05163   Human cytomegalovirus infection tod05166   Human T-cell leukemia virus 1 infection tod05200   Pathways in cancer tod05207   Chemical carcinogenesis - receptor activation tod05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:tod00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     119257456 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     119257456 (ADCY5)    04371 Apelin signaling pathway     119257456 (ADCY5)    04072 Phospholipase D signaling pathway     119257456 (ADCY5)    04024 cAMP signaling pathway     119257456 (ADCY5)    04022 cGMP-PKG signaling pathway     119257456 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     119257456 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     119257456 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     119257456 (ADCY5)    04062 Chemokine signaling pathway     119257456 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     119257456 (ADCY5)    04923 Regulation of lipolysis in adipocytes     119257456 (ADCY5)    04912 GnRH signaling pathway     119257456 (ADCY5)    04913 Ovarian steroidogenesis     119257456 (ADCY5)    04915 Estrogen signaling pathway     119257456 (ADCY5)    04914 Progesterone-mediated oocyte maturation     119257456 (ADCY5)    04921 Oxytocin signaling pathway     119257456 (ADCY5)    04926 Relaxin signaling pathway     119257456 (ADCY5)    04935 Growth hormone synthesis, secretion and action     119257456 (ADCY5)    04918 Thyroid hormone synthesis     119257456 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     119257456 (ADCY5)    04916 Melanogenesis     119257456 (ADCY5)    04924 Renin secretion     119257456 (ADCY5)    04925 Aldosterone synthesis and secretion     119257456 (ADCY5)    04927 Cortisol synthesis and secretion     119257456 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     119257456 (ADCY5)    04270 Vascular smooth muscle contraction     119257456 (ADCY5)   09154 Digestive system    04970 Salivary secretion     119257456 (ADCY5)    04971 Gastric acid secretion     119257456 (ADCY5)    04972 Pancreatic secretion     119257456 (ADCY5)    04976 Bile secretion     119257456 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     119257456 (ADCY5)    04727 GABAergic synapse     119257456 (ADCY5)    04725 Cholinergic synapse     119257456 (ADCY5)    04728 Dopaminergic synapse     119257456 (ADCY5)    04726 Serotonergic synapse     119257456 (ADCY5)    04723 Retrograde endocannabinoid signaling     119257456 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     119257456 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     119257456 (ADCY5)    04213 Longevity regulating pathway - multiple species     119257456 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     119257456 (ADCY5)    04714 Thermogenesis     119257456 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     119257456 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     119257456 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     119257456 (ADCY5)    05163 Human cytomegalovirus infection     119257456 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     119257456 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     119257456 (ADCY5)    05031 Amphetamine addiction     119257456 (ADCY5)    05032 Morphine addiction     119257456 (ADCY5)    05034 Alcoholism     119257456 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     119257456 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     119257456 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     119257456 (ADCY5) Enzymes [BR:tod01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      119257456 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  119257456 NCBI-ProteinID:  XP_037381329 LinkDB All DBs Position Unknown AA seq 1263 aa AA seqDB search MSGSKSASPPGYAAQTAAAPASRGGQEHRSAWGEADPRANGYPHAPGGSTRGSAKKPGGA VTPQQQQQQQQRLAGRWRGDDDGDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSR RQRRGAAGGGSTRAPPAGGGGGSAAAAAAAGGTEVRPRSLELGLDERRGKGRAADHLEAG AVEGEDRPGDGGSSAGSGGGPGAALSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLN QSSLTMLMAVLVLVCLVMLAFHAARPPVQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHM GLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLS ALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQAR LHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGF TSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCV EMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAG GKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAK MNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDE FLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFV QITIVPHSMFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPGPLQTLSRKIVRSKMNSTLVG VFTIILVFLSAFVNMFMCNSKDLFGCLAYEHNISTSQVNACHVVESAVNYSLGDEQGFCG SSWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPVVTLFDNA DLLVTANAIDFNNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLW KLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIA NFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDS TYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDI WGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGP PLS NT seq 3792 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgcgagccccccgggctacgcggcgcagaccgcagcggcgccc gcgtcccggggaggccaggagcaccgctccgcgtggggcgaggccgacccccgcgccaac ggctacccgcacgcccccgggggctccacccgcggctccgccaagaaacccgggggggcg gtgaccccgcagcagcagcagcagcagcagcagcgcctggccggccgctggcgcggcgac gacgacggcgaccccccgctgagcggcgacgaccccctggccgggggcttcggcttcagc ttccgctccaagtccgcctggcaggagcgcggcggcgacgactgtggtcggggcagccgc cggcagcggcggggcgcggccggcgggggcagcacccgggcgccccctgcgggcggcggc gggggctcggcggcggcggccgcggccgcgggcgggaccgaggtgcgcccccgctccctg gagctcggcctggacgagcggcgaggcaagggccgagcggccgaccatctggaggccggc gccgtcgagggcgaagaccggccgggggatggcggcagctcggcgggctccggcggcggc cccggcgcggcgctgtccctgggcgcctgctgcctggcgctgctgcagatcttccgctcc aagaagttcccgtcggacaagctggagcggctgtaccagcgctacttcttccgtctgaac cagagcagcctcaccatgctcatggcagtgctcgtgctcgtgtgcctcgtcatgttggcc ttccacgcggcgcggcccccggtccagctgccctacctggcggtgctggccgcggccgtg ggcgtgatcctcgtcatggccgtgctctgcaaccgcgcagccttccaccaggaccacatg ggcctggcctgctacgcactcatcgccgtggtgctggccgtccaggtggtgggcctgctg ctgccccagccacgcagcgcctccgagggcatctggtggacggtgttcttcatctacacc atctacacgctgctgcccgtgcgcatgcgagctgctgtgctcagcggggttctcctgtct gccctccacctggccatcgccctgcgcaccaacgcccaggaccagttcttgcttaagcag cttgtctccaatgtcctcattttctcctgcaccaacatcgtgggcgtctgcacccactat ccggctgaggtgtcccagagacaggccttccaggagacccgggagtgcatccaggctcga ctccactctcagcgggaaaaccagcaacaggagcggctcctgctgtctgtccttccccgt catgttgccatggaaatgaaagcagacatcaatgccaagcaggaggatatgatgttccat aagatttacatccagaaacatgacaacgtgagcatcctgtttgctgacatcgagggcttc accagcctggcatcccagtgcactgcccaggagctggtcatgaccctcaacgagctcttc gcccgcttcgacaaactggctgcagagaatcactgtttacgtattaagatcctgggggat tgttattactgcgtctcagggctgcctgaagcgagggctgaccacgcccactgctgcgtg gagatgggcatggacatgattgaggccatctcgttggtccgggaggtgacaggggtgaac gtgaacatgcgcgtgggaattcacagcgggcgagtacactgcggtgtccttggtctcagg aagtggcagttcgacgtctggtctaacgacgtcactctggccaaccacatggaagctgga ggcaaggctggacgcatccacatcaccaaggccacgctcaactacctgaatggagactac gaggtggagccaggctgtgggggcgagcgcaatgcctacctcaaggaacatagcatcgag accttcctcatcctgcgctgcacccaaaagaggaaagaagagaaggccatgatcgccaag atgaatcgccagagaaccaactccatcgggcacaacccaccgcactggggggccgagcgc cccttctacaaccacctaggcggcaaccaggtgtccaaggagatgaaacggatgggcttt gaagaccccaaggacaagaatgcccaggaaagtgcaaaccctgaggatgaagtggatgag tttctggggcgagccattgacgccaggagcatcgacaggctgcggtctgagcatgttcgc aagttcctcctgaccttcagggagcctgacttagagaagaagtactccaagcaggtggat gaccgattcggtgcctatgtggcgtgtgcctcgctcgtattcctcttcatctgctttgtc cagatcaccatcgtgccccactccatgttcatgttgagtttctacctgacctgtttcctg ctgctgactttggtggtgttcgtgtccgtgatctactcctgtgtgaagctcttcccaggc cctctgcagaccctctccaggaagatcgtgcggtccaagatgaacagcaccttagtcggg gtgttcaccatcatcctggtgttcctgtcggcttttgtcaacatgttcatgtgcaactcc aaggacctgttcggctgcctggcatacgagcacaacatcagcaccagccaggtcaacgcg tgccacgtggtagagtcggctgtcaactatagcctgggtgatgagcagggcttctgtggc agctcctggcccaactgcaactttcctgagtacttcacctacagcgtgctgctcagcctg ctggcctgctccgtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggcc atcgagctcatctacgttctcgtcgtcgaggtgcccgtggtcactctctttgacaatgct gacctgctggtcaccgccaacgccatagacttcaacaacaacgggacctcccagtgtccc gagcatgcgaccaaggtggcgctgaaggtggtgacacccatcatcatctcggtgttcgtg ctggccctgtacctgcatgcccagcaagtggagtccaccgcccgcctcgacttcctctgg aaactgcaggccacggaggagaaggaggagatggaggagctgcaggcctacaaccggcgg ctgctgcacaacatcctgcccaaggacgtggcggcccacttcctggcccgtgagcggcgc aacgacgagctttactatcagtcgtgcgagtgcgtggccgtcatgttcgcctccatcgcc aacttctctgagttctatgtggagctggaggccaacaacgagggcgtggagtgcctgcgg ctgctcaacgagatcatcgccgactttgacgagatcatcagcgaggatcggtttaggcag ctggaaaagatcaagaccattggcagcacctacatggctgcctcaggcctcaacgactcc acctatgacaaggtgggcaagacccacatcaaagctctggccgactttgccatgaagctg atggaccaaatgaagtacatcaacgagcactccttcaacaacttccagatgaagattgga ctcaatattggccccgtggtggctggggtgataggggctcgcaagcctcagtacgacatc tggggcaatacagtgaatgtggccagccgcatggacagcactggtgtgcccgatcgtatc caggtcaccacggacatgtaccaagtgctggctgccaatacctaccagctggagtgccgg ggtgtggtcaaagtcaagggcaaaggcgagatgatgacctacttcctcaacggagggccc ccactcagttag

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