Treponema pallidum Fribourg-Blanc: TPFB_0512
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Entry
TPFB_0512 CDS
T02651
Symbol
ispDF
Name
(GenBank) bifunctional 2-C-methyl-D-erythritol 4-phosphatecytidylyltransferase/2-C-methyl-D-erythritol2, 4-cyclodiphosphate synthase
KO
K12506
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:
2.7.7.60
4.6.1.12
]
Organism
tpb
Treponema pallidum Fribourg-Blanc
Pathway
tpb00900
Terpenoid backbone biosynthesis
tpb01100
Metabolic pathways
tpb01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
tpb00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
TPFB_0512 (ispDF)
Enzymes [BR:
tpb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
TPFB_0512 (ispDF)
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
TPFB_0512 (ispDF)
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GFIT
Motif
Pfam:
YgbB
IspD
CV_2116-like
Motif
Other DBs
NCBI-ProteinID:
AGK84156
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All DBs
Position
549907..551154
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AA seq
415 aa
AA seq
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MTRAALLVTAAGSSARMRRGGACVQKKEYLPLTSRQPGVCLLSEILVRALEARSFFLVVV
TVPAGEVAYAESQVACDSRLSAFPSRTRPVILYVPGAHTRSASVRAGLDAMATHAPDVVL
VHDGARPFVSVALIHSVLEATCRYGAAVPVIEATDTPKGVAADGSIETHLIRSRVRLAQT
PQGFCYASLCAAHHRAATDGEQYTDDSELYARYGGTVHVCAGERSNVKITYPEDLEQRAS
EPALTRGISVLPCTEEGALRVGLGTDMHALCAGRPLILAGIHIPSKKGAQGHSDADVLAH
ASIDALLGAAGLGDIGTFFPSCDGRWKDAHSCALLRHTWQLVRAACWRLVNLDAVVCLEQ
PALHPFREAMRASLAQALDTHVTRVFVKAKTAERLGPVGSGAAVTAQVVVLLKKV
NT seq
1248 nt
NT seq
+upstream
nt +downstream
nt
gtgacccgcgccgcgttgcttgtcaccgctgcaggcagctctgcacgcatgcgcagaggt
ggtgcgtgtgtgcagaaaaaggagtacttgccgttaacttccaggcagcctggtgtctgc
ctcctttctgagatactcgtgcgtgcccttgaggcgcggtcgttcttccttgtcgttgtt
accgttcctgcaggtgaagttgcgtacgcagaaagtcaagtggcgtgtgattcgcgtctt
tcggcgttcccgtctcgtacgcgtccagtcattctttacgtgccgggtgcacatacacgc
agtgcgtctgtgcgcgcggggcttgacgcgatggctacgcatgcgcccgatgtggtcctg
gtgcacgacggcgcacgtccctttgtgagtgttgcgcttattcattctgtacttgaggct
acctgtcgctatggagcggcagtgccggttatagaggcgacggatactcccaagggtgtt
gctgccgatgggagtatcgaaacgcatcttatacggagtcgagtgcgcttagcacaaacc
cctcagggtttttgctacgcgtcgctgtgcgctgcccatcaccgcgctgctactgatggg
gaacagtatactgatgacagcgagctgtacgctcgctacggagggaccgtacatgtctgc
gccggtgaacgcagtaatgtaaagattacctatccggaggatctggagcagcgggcatcg
gagcctgctctcacgagggggatatcagtcctgccgtgtacggaagaaggtgccctgcgc
gttggactggggactgatatgcacgcgctgtgtgcaggaagaccgctgatacttgcaggg
atacatattcccagtaagaagggagcgcagggtcattcggatgcagacgttcttgcgcat
gcgagcattgacgcccttttgggtgcagcaggcctgggggatattggcacgtttttcccc
tcttgtgacggacgatggaaagacgcacattcttgcgcgttgctccgccatacctggcaa
ctggtgcgcgcagcgtgctggcggctggtgaatctcgatgctgttgtctgtcttgagcag
cctgcattacacccatttcgggaagcgatgcgcgcatcgcttgcgcaggccctggacacg
cacgtaacacgtgtttttgttaaggcaaagactgccgaacgcctcggacctgttggatct
ggtgcggcggttaccgcacaggtagtggtacttttgaaaaaggtatga
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