Treponema pallidum subsp. pallidum Chicago: TPChic_0446
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Entry
TPChic_0446 CDS
T01868
Symbol
ispG
Name
(GenBank) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
KO
K03526
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:
1.17.7.1
1.17.7.3
]
Organism
tph
Treponema pallidum subsp. pallidum Chicago
Pathway
tph00900
Terpenoid backbone biosynthesis
tph01100
Metabolic pathways
tph01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
tph00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
TPChic_0446 (ispG)
Enzymes [BR:
tph01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.7 With an iron-sulfur protein as acceptor
1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
TPChic_0446 (ispG)
1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
TPChic_0446 (ispG)
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GFIT
Motif
Pfam:
GcpE
Motif
Other DBs
NCBI-ProteinID:
ADD72567
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Position
473332..474591
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AA seq
419 aa
AA seq
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MNQRDERAARQPEEKVDSSAGVSPCNSPYGSGLLDVPLKLRPRASHYRARSLVIGGKEHV
RALPLGGDAPIPIQTMWKEPLIGADLQSIVDRLLELEQLGCDVVRFAVPDRESAELFVAL
CARTRMPLVADIHFDYRLALRCMDGPVAKVRINPGNIGVRERVRAVVEKARATGTALRIG
VNTGSLPGVVKRAVAARYADGMQSVNARAEALVQTAFAEAAYLDQLHFDRVVLSLKASTV
AETVRANELFAQQSDIPLHLGVTEAGPLVSGIVKSTLAFSQLLSRNIGATVRVSLSDSME
HEVLAAREILAECGKRAGGVRLVSCPRCGRIGFDVHAFVRRWQKELFSLKKDITVAVMGC
VVNGPGEGKHADLGISGAEDSVIFFKRGKIVRRIQVRDLCADERTRIIDAAFKEELSSL
NT seq
1260 nt
NT seq
+upstream
nt +downstream
nt
gtgaatcagagggacgagcgtgctgcgcggcagccagaggaaaaggtggattcatctgcc
ggtgtgtctccctgcaatagtccgtatgggagtggacttttggatgttccattaaaatta
agaccgcgtgcgtcccactaccgtgcacgatcattggtaattggaggaaaggaacatgtg
cgtgcgttgcctcttgggggtgacgcaccgattcctatccaaacaatgtggaaagaaccg
ctcattggtgcagatctccaatccattgtggaccgtcttttggaacttgaacaattaggg
tgtgacgttgtgcgttttgccgttcctgacagggaatcggctgagctttttgtggcgctt
tgcgcgcgcacgcgtatgccgcttgttgcagacattcactttgattaccggcttgcgctg
cggtgtatggacggaccggtagcgaaagtgcgtattaacccggggaatatcggtgtgcgt
gagcgcgtgcgtgcggtggtagaaaaggctcgagcaaccggcactgctttgcgtattggg
gtgaataccggttctctgccgggtgtggtgaagcgcgcagttgcggcgcgttacgcggat
gggatgcagtcagtgaatgcgcgtgcagaagcgttggtgcaaactgcctttgcagaagct
gcgtatctagatcagttacactttgatcgggttgtcctttctctgaaggcttctacggtt
gcagagacggtacgtgccaacgaactttttgcgcagcagtctgatattcccttgcacctt
ggagtaacagaagcaggcccgcttgtttccggtattgtcaaaagtacacttgcattttcc
caattactgtcacgcaatattggtgccacggtgcgggtgagtctttcagatagcatggag
catgaggtgctggctgcgcgagaaattcttgctgaatgcggtaaacgggctggtggggtt
cgtttagtgtcatgtccgcgctgtggcaggattggttttgacgtacacgcatttgtgcgg
aggtggcaaaaggaactgttcagtttgaaaaaggatatcacggttgcggttatgggctgt
gtagtgaatggtcctggagaaggaaagcatgcggatctcggtatcagcggtgcggaggat
tcggtgattttttttaagcggggaaagatagtgcgtcgcattcaggtacgtgatctttgc
gcagacgagcgcacgcgcataatagacgcagcgtttaaagaggaattgtcaagtttatga
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