Treponema pallidum subsp. pallidum Mexico A: TPAMA_0340
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Entry
TPAMA_0340 CDS
T02273
Symbol
folC
Name
(GenBank) bifunctional dihydrofolate synthase/tetrahydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tpo
Treponema pallidum subsp. pallidum Mexico A
Pathway
tpo00790
Folate biosynthesis
tpo01100
Metabolic pathways
tpo01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
tpo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
TPAMA_0340 (folC)
Enzymes [BR:
tpo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
TPAMA_0340 (folC)
6.3.2.17 tetrahydrofolate synthase
TPAMA_0340 (folC)
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AFU66349
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Position
complement(363195..364667)
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AA seq
490 aa
AA seq
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MSDLSNVHQFSFPARIAASSVPHIIVRPSAHGVSHIPVHSFQDFYAWVERIRTLEKMPPS
GTPPLHRMTALARALCNPHNAYQSIHVAGTKGKGSSARMLAAILNEIGFNTGLYASPHVM
DPRERITRAGVFFSPAEYASACTHVYHTVKKTENLRDYGQATWFELITLLAFMLFAQQRM
EWSVFEVGLGGRLDATNIICPSICLLLPIEQEHTRILGTRIKSIAKEKGGIIKPYTPIFC
FDQPEDALHVFKHIAREKHAPFFYLPDMVTHIESSIKHFTHTATLSFNAAHPVGRLFARN
IHCTLALCDIVQAKNAALAACAAKYLFPTVSETLIERGLSRAYVPARFEIMQEDPLIVID
GAHTTQSIRCACRTFSSLLPSAQYILLFACAADKAVSQFPPLFSHAASEIFLTIPGTSKH
ADIQKTYHAFRTTFHQTVPIFWSEDFASIISRALYASFAQRKALLAIGSFYLAAEVKRIY
ARTCHTLPNR
NT seq
1473 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaccttagcaatgtacatcagttctctttcccggcaaggattgctgcctcttcc
gtaccgcatattatagtgcgaccgagcgcacacggagtttcacatataccggtgcattct
tttcaagatttttacgcctgggttgagcgcattcgcacgcttgagaaaatgcccccaagc
ggcacaccacctctgcacaggatgactgcacttgcacgcgcgctttgtaatccacacaac
gcatatcagagcatccatgttgcgggcacgaagggaaaaggttccagcgcacgtatgctt
gcagcgatactcaatgaaattggattcaacaccgggctatacgcttctcctcacgttatg
gatccgagagagagaataacacgcgcgggtgtgtttttttcacctgccgagtatgcaagc
gcgtgcacacacgtataccacacggtgaaaaaaacagagaatctgcgcgactacggccag
gcgacgtggtttgagcttataacgctactggcgttcatgctatttgcacaacaacgcatg
gaatggtccgtttttgaagtaggacttggaggaagactagatgcaacaaacatcatttgt
cctagtatctgtctccttctccccatagaacaagaacacacgcgcatattaggaacacgt
ataaaaagtattgcaaaagaaaagggcggcattatcaaaccctatacgcctattttttgt
tttgatcagccagaagatgcattgcacgtttttaaacatatcgcgcgagaaaaacatgct
cccttcttttacttaccagatatggtcacacatattgaaagttcaataaaacacttcaca
cacactgcaactctcagttttaacgccgcgcatcctgttggcagattattcgctcgaaat
atacactgcacactcgcgttatgcgatattgttcaggcaaaaaatgcagcactggctgcg
tgcgcggcaaaatatttatttcctaccgtgagcgaaacgttaatcgagcggggactgtcc
cgtgcatacgtgccagcacgctttgaaattatgcaggaagatccactcatagtgattgac
ggtgcgcacactacgcagagtatacggtgcgcatgtcgtacgttctcttctttactacct
tctgcacaatacattttactctttgcgtgcgcggcggacaaagcagtgtcccagttcccc
cctcttttttcacatgccgccagcgaaatttttttaaccataccgggcacatctaaacat
gcagatatacaaaaaacataccacgcgtttcgtacgacatttcaccaaacagtcccaatt
ttttggagcgaagactttgcgtcaattatttcccgtgcactgtatgccagttttgcgcaa
cgtaaagcgctccttgccatcggttctttctatttagctgctgaagtaaaacgcatatac
gcacgcacctgccacaccctacctaaccgataa
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