Thiothrix subterranea: HMY34_04435
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Entry
HMY34_04435 CDS
T07831
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tsb
Thiothrix subterranea
Pathway
tsb00790
Folate biosynthesis
tsb01100
Metabolic pathways
tsb01240
Biosynthesis of cofactors
Module
tsb_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
tsb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HMY34_04435 (folC)
Enzymes [BR:
tsb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HMY34_04435 (folC)
6.3.2.17 tetrahydrofolate synthase
HMY34_04435 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QQZ28063
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Position
complement(930582..931814)
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AA seq
410 aa
AA seq
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MKTLDDWLRWQETQFLTEIKLGLDRIRCVAERMGLLSVPVPLLTVGGTNGKGSTCAMLTR
ILLLQGYKVGTYTSPHLLRYNERIALNGVPVRNADICAAFAAIDKARDDIDLTYFEFGTL
AAVWCFLQAKVDVIVLEVGLGGRLDACNLWDADVAIITSIGIDHVEWLGSTREAIGYEKS
GIMRAGKPVVCGDPQPPASIAREAARIGADLWQLGRNFSVEHVPQPALVGDVQRQNAAVV
VTALQRLADKLPVSPDAIAEGLASVSLMGRMQRIRAEPEVILDVAHNPHAATELAGWLKK
NPVNGKTFAIFSILADKDIAGVLKIMASAVDEWYVVALSSKRALSQDDLLALMRSNGISQ
PIHAYPDFQSAWNVMVLSAEKQDRVVAFGSFLVVSAMLEIDVSPHGAGSA
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
ttgaaaacgctcgatgattggttgcgttggcaggaaacgcaattcttgaccgaaatcaag
ctggggctggatcggattcgttgcgtcgctgagcgcatgggcttgctgtctgtacccgtg
ccactgctgacggtgggcgggacgaacggcaaaggttccacctgcgccatgttaacgcgg
attttgctgctgcaaggttacaaggtcggtacgtatacttcccctcacttactgcgctac
aacgaacgcattgcgctgaatggcgtaccggtaaggaatgcggacatttgtgccgctttc
gccgcgattgataaggctcgcgatgatattgatttgacctactttgaattcggcacactg
gcggcggtgtggtgttttttgcaagccaaggttgatgtgattgtgttggaagtcgggctg
ggcgggcgtttggatgcgtgcaatctgtgggatgcggatgtcgcgattatcaccagcatt
ggcattgatcacgtggaatggctgggcagtactcgcgaagccatcggctatgaaaaatct
ggcattatgcgggcaggcaaaccggtagtttgcggcgacccgcagccacccgccagcatt
gcgcgtgaagccgcgcgtatcggggcggatttgtggcaattggggcggaatttcagcgtc
gagcatgtgccacagcctgcattggtgggcgatgtgcaacgtcaaaacgcggcggttgtg
gtgacagctttgcaacgattggcggataaattgcctgtttccccagatgcaattgctgaa
ggcttagccagtgtgagcctgatggggcggatgcagcggattcgagcagaaccggaagtc
atccttgatgtcgcgcacaatccccatgcagcgactgaattggcaggatggttgaaaaaa
aatccagtaaacggcaaaacatttgcaattttttctatacttgcagataaggatattgct
ggggtgctgaaaatcatggcgtcggcggtggatgaatggtacgtagtggcattgtccagc
aagcgggcgctcagtcaggatgatctgttagcactcatgcgttccaatggcataagccaa
ccgattcatgcctatcctgatttccagagtgcatggaacgttatggttttaagcgcagaa
aaacaggacagagtagttgcattcggttcttttctggtagtatccgctatgctggaaata
gacgtttctccccatggcgctggttctgcctga
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