Thiothrix subterranea: HMY34_05245
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Entry
HMY34_05245 CDS
T07831
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
tsb
Thiothrix subterranea
Pathway
tsb00230
Purine metabolism
tsb01100
Metabolic pathways
tsb01110
Biosynthesis of secondary metabolites
Module
tsb_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tsb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
HMY34_05245 (purL)
Enzymes [BR:
tsb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
HMY34_05245 (purL)
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Gene cluster
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Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
QQZ28207
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Position
1099357..1103247
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AA seq
1296 aa
AA seq
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MLIFPGSVALSDFRRNKLLSALQAIVPTITAVQAEYVHFVRNSRELHPDEHAQLQALLTY
EEVQGSHAFSGTLLLVTPRKGTISPWSSKASDIAHNCGLTMVERIERGIAYDIQTTAALS
EAERLAIAALLHDRMTEMVLTDLQDAVVLFSEAEPAALRYVDISNDPKAALAKANTDWGL
ALSADEIDYLAENYAELQRNPTDVELMMFAQANSEHCRHKIFNADWIIDGKEQPKSLFAM
IRNTHAHAPEGILSAYHDNASVIEGPLATRFLTDVKTGEYHYTNEPVHILMKVETHNHPT
AISPFAGAATGSGGEIRDEGATGNGSKPKAGLSGFSVSNLRIPGYAQPWEHDFGKPDRIV
SALDIMLEGPIGAAAFNNEFGRPNITGYFRTFEMQAPGAKGTELRGYHKPIMIAGGMGNI
RENNINKNPLPEGTPIIVLGGPAMLIGLGGGAASSMASGTSAENLDFASVQRGNPEMQRR
CQEVIDRCVALGAENPILSIHDVGAGGISNAIPEIVNDAGRGGRFELRAVPNAELGMAPM
EIWSNEAQERYVLAIAEDRLDTFRALCERERAVYAVVGNATVEQQLLVGDSLFDNNPVNL
PMNVLLGKPPKMLRDVHHQTFHKPEIDLSGIELPEAIERVLRLPTVASKSFLITIGDRTV
TGMVTRDQMVGAWQVPVADVAVTSSDYTTNFGEAMAMGERTPIALVNPAASGRMAIGEAL
TNIAAADIANIRNIRLSANWMAAAGYHGEDAALFDTVKAVGEELCPRLGLAIPVGKDSLS
MKTVWQQDGENREMIAPLSLIVTAFSPVQDIRKTLTPALCSDVGDTDLILVDLGKGRNRL
AASALAQVYGQVGHHAPDVDNPDALKAFFDTVQDLRGENLILAYHDRADGGLLATLAEMS
FAGHVGVTACIGQVSEQLLPALFSEELGAVLQVRHCDTDAVLEAFREAGLAHCTHVIGEL
NDSDELVLTFANKEVYRAPRATLQKIWAETSYRMQALRDNADCAAQEFERLDDVQDPGLP
FAPTFELDEDVAAPYIRTGVRPAIAVLREQGVNGQVEMAAAFDRAGFKAVDVHMTDIISG
RVKLKDFKGLVACGGFSYGDVLGAGGGWAKTILMNPRASDEFAAFFARQDSFGLGVCNGC
QMFSQLRDMIPGAAHWPRFYRNRSEQFEARYSAVEVLESPSLFLQGMAGSKLPIAVAHGE
GRAVFDTATAEGMLAEGLVGLRYVDNRGNATEHYPENPNGSPLGITGVTTADGRFTIMMP
HPERLFRAVQHSWKPDDTGEDGAWLRMFRNARVWVG
NT seq
3891 nt
NT seq
+upstream
nt +downstream
nt
atgctgatcttccccggtagcgttgccctctccgattttcgccgcaacaagctgttgagc
gccttgcaagccatcgtgcccacgatcaccgctgtgcaagccgaatacgtccatttcgtg
cgcaacagccgcgaactgcaccccgacgaacacgcccagttgcaagcgttgctgacctac
gaagaagtgcaaggcagccacgcgttcagcggcacattgctgctcgtcaccccgcgcaaa
ggcacgatttcgccttggtcaagcaaagccagcgacatcgcccacaactgcggcttgacg
atggtggaacgcatcgaacgcggcattgcctacgacatccaaaccactgccgccctgtct
gaagccgagcgtctcgccattgccgcgctgttgcacgaccgcatgaccgaaatggtactg
accgacctgcaagatgccgtcgtcctgttcagcgaagccgaacccgccgccttacgctac
gttgacatcagcaatgaccccaaagccgcgctcgccaaagccaacaccgactggggcttg
gcgctgtcagcggatgaaatcgactacctcgcggaaaactacgccgaactccagcgcaac
cccaccgacgtagagttgatgatgttcgcgcaagccaactccgaacattgccgccacaaa
atcttcaacgccgactggattatcgacggcaaagaacagcccaaatcgctgtttgccatg
atccgcaacacccacgcgcacgcgcccgaaggcattctttccgcctaccatgacaacgcc
tccgtcatcgaaggcccgttggcaacgcgctttttgaccgacgtaaaaaccggcgaatac
cactacaccaacgaacccgtccacatcctcatgaaggtggaaactcacaaccaccccacc
gccatttccccgtttgcgggtgctgcaacaggttcgggcggcgaaatccgcgatgaaggc
gcaaccggcaacggctcgaaacccaaggcgggcttgagcggcttctcggtatccaatctg
cgcatccccggctacgcccagccatgggaacacgattttggcaaacccgaccgcatcgtt
tccgccctcgacattatgctcgaaggccctattggtgccgccgcgttcaacaacgaattc
ggtcgccccaatatcaccggctatttccgcacctttgaaatgcaagcccccggcgcaaaa
ggtacggaactgcgtggctaccacaagccgatcatgattgcaggcggcatgggcaatatc
cgcgaaaacaacatcaataagaacccgctgcctgaaggcacaccgatcatcgtcctcggc
ggccccgccatgctgatcggtttaggcggcggtgcggcttcctcaatggcaagcggcacg
agtgcggaaaacctcgacttcgcctctgtgcagcgcggcaaccccgaaatgcaacgccgt
tgccaagaagtcatcgaccgttgcgtagccttgggcgcggaaaaccccatcctctccatc
cacgacgtaggcgctggcggtatttccaacgccatccccgaaatcgtcaacgatgccgga
cgcggcggacgctttgaactccgtgccgttcccaacgccgaactcggcatggcaccaatg
gaaatctggagcaacgaagcgcaagaacgctacgttctcgccattgccgaagaccgcctc
gacaccttccgcgccctgtgcgaacgcgaacgcgccgtctacgccgtggtcgggaatgct
acggttgaacaacaattgctggttggcgattccctgtttgacaacaatccggtgaatttg
ccgatgaacgtgctgctcggcaaaccgccgaaaatgctgcgtgacgtgcatcaccaaact
ttccacaagccggaaatcgacctgagcggcattgagttgccggaggcgattgagcgcgta
ttgcgcttgccgactgttgcctccaagtccttcctgattaccatcggcgaccgcacggta
acgggcatggtgacccgcgaccaaatggtcggagcatggcaagtgccggtggcggatgtg
gcggtcacctccagcgattacaccaccaatttcggcgaagcgatggcaatgggtgaacgc
accccgattgcgctggtgaatccggcagcatcggggcgcatggcgattggcgaagccctc
accaatattgcagcggcagacattgccaatatccgcaacattcgtctgtccgccaactgg
atggcggcggcaggctatcacggcgaagatgccgcgttgtttgacaccgtgaaagcggtc
ggcgaagaactgtgcccgcgtttgggtctagcaattccggttggcaaagactccctgtcg
atgaaaaccgtatggcagcaagacggcgaaaaccgcgaaatgatcgcgccgctttccttg
atcgtcaccgcgttttcgcctgtgcaggacattcgcaaaaccctgactccggcattgtgc
agcgacgttggcgataccgacctgattctggtggatctcggcaaagggcgtaaccgattg
gcagcgtctgcactggcgcaagtctacggacaagtcgggcatcacgcgccggacgtggat
aaccctgacgcgctcaaagccttcttcgataccgtgcaagatttacgtggcgaaaacctg
attttggcgtaccacgaccgtgccgatggcggcttgctggcaacactggcagaaatgagc
tttgcggggcatgtgggcgtgaccgcttgcatcgggcaggtgagtgagcaattgctgccc
gcgctattcagcgaagaactcggcgcggtattgcaagtgcgccattgcgatacggatgcg
gtgttggaagcgttccgcgaagctgggctggcgcattgcactcatgtcattggcgaattg
aacgacagcgacgaattggtgctgacctttgctaacaaagaagtgtaccgcgctccacgt
gctactttgcaaaaaatctgggcagaaaccagctaccggatgcaggcgttgcgtgacaat
gccgattgcgccgcgcaagaatttgagcggctggatgatgtgcaagaccccggtttgcca
ttcgcgccaacctttgagttggatgaggatgtggcagcgccgtatatccgtaccggagta
cgtccggcgattgcggtattgcgtgagcaaggtgtgaacgggcaggtggaaatggcggcg
gcgtttgaccgtgccggtttcaaggcggttgacgtacacatgaccgacattatcagtggg
cgtgtgaagttgaaagatttcaaaggcttggtggcgtgcggcggcttctcctacggcgat
gtgttgggcgctggcggcggctgggcgaaaaccattctgatgaatccgcgtgccagtgat
gaatttgcggcgttttttgcgcggcaagattccttcgggctgggcgtgtgcaatggctgc
caaatgttctcgcaattgcgtgacatgatccccggtgcggcacattggccacgtttctac
cgcaaccgttccgagcagtttgaggcgcgttattcggcagtcgaggtgttggaatcgccg
tcgttgttcctgcaaggcatggctggctcgaagctgccgattgcggtagcgcatggtgaa
gggcgggcggtgtttgataccgctacggctgaagggatgttggcggaaggcttggtcggc
ttgcgttatgtggataatcgcggcaatgccactgagcattaccccgaaaaccccaacggt
tcgccgttgggcatcacgggcgttaccacggcggatgggcgttttaccatcatgatgccg
caccccgaacgcttgtttcgggcggtgcagcattcatggaagccggatgatacgggtgaa
gatggtgcgtggttgcggatgttccgcaatgcgcgggtttgggtaggctaa
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