Thermococcus sibiricus: TSIB_0486
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Entry
TSIB_0486 CDS
T00928
Name
(GenBank) Phosphopantothenoylcysteine synthetase/decarboxylase
KO
K13038
phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:
4.1.1.36
6.3.2.5
]
Organism
tsi
Thermococcus sibiricus
Pathway
tsi00770
Pantothenate and CoA biosynthesis
tsi01100
Metabolic pathways
tsi01240
Biosynthesis of cofactors
Module
tsi_M00914
Coenzyme A biosynthesis, archaea, 2-oxoisovalerate => 4-phosphopantoate => CoA
Brite
KEGG Orthology (KO) [BR:
tsi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
TSIB_0486
Enzymes [BR:
tsi01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.36 phosphopantothenoylcysteine decarboxylase
TSIB_0486
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.5 phosphopantothenate---cysteine ligase (CTP)
TSIB_0486
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GFIT
Motif
Pfam:
DFP
Flavoprotein
Usp
PTS_IIB
Motif
Other DBs
NCBI-ProteinID:
ACS89552
UniProt:
C6A1Q7
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All DBs
Position
459824..461053
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AA seq
409 aa
AA seq
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MVKKMLHHVKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSA
QKIIHPYAMEFATGNPVVTEITGFVEHVELAGEHENKVDLVLVCPATANTISKIACGIDD
TPVTTVVTTAFAHTPIMIAPAMHFTMYEHPIVKENIEKLKKLGVEFIGSRFEEGKAKVAS
VEEIVYHVIKKLHRKDLAGKRVLVTAGATREYIDPIRFITNRSSGKMGVALAEEAEFRGA
EVTLIRTKGSVPSFVENQVEVETVEEMLEVIENELNSKKYDIVILAAAVSDFRIKDKVSV
KIKSGKALTLELEPTPKIIDRVKELQPDVFLVGFKAETGLSEDELIEAARKQIERAGSDI
VVANTLKAFGSEENEAILVGKDFTKKLPRMNKRELAERLFDEIISMISG
NT seq
1230 nt
NT seq
+upstream
nt +downstream
nt
ttggtgaagaaaatgcttcatcatgtcaagctgatatatgcgacaaagagcaggaagctt
gttgggaagaaaatagtccttgctatacctggaagtatagcggccgttgagtgtgtaaag
ctcgcaagggagctcataagacatggagctgaagttcatgccgttatgagcccaagtgcc
caaaagataatccatccctatgctatggaatttgctactggcaatccggttgtcacagag
atcacgggatttgtagagcatgttgaacttgctggagagcacgaaaacaaagtagatttg
gtcttggtctgtcctgcaacggccaatactatatcgaaaatagcctgtggaattgatgat
acaccagttacaactgtcgtaacgactgcttttgcccatactccaataatgattgctcca
gctatgcacttcacaatgtatgagcacccgatagttaaggagaacatagagaagctcaaa
aagctcggagttgaatttatcgggtctagattcgaggaaggaaaggcaaaggtggcaagc
gttgaagaaattgtttatcacgtaattaaaaagctccacagaaaagatctggctggaaag
agagtcctcgtaactgctggagcaacgagagaatacattgacccaataaggttcataaca
aacaggagcagcggcaagatgggtgtagcattagcagaggaggcggaattcaggggggca
gaggttactttgataagaaccaaggggagtgtgccaagctttgtggagaaccaagttgaa
gttgagaccgttgaagaaatgcttgaggtaatagagaacgagctgaatagcaagaagtac
gatattgttattctggctgcggccgtaagcgatttccgtattaaggataaggtcagtgta
aagataaagagcggaaaagctttaacgcttgagcttgaacctacgccgaagataatagac
agagttaaggaacttcaaccagatgttttcctcgtcggtttcaaagctgaaacaggcctc
agcgaggatgagctaattgaagccgcgaggaagcaaatcgaaagggctggaagcgacata
gtcgtggcaaacacactcaaagccttcggcagcgaggagaacgaggccatactcgttgga
aaagactttacaaagaaactgccgagaatgaacaagcgcgagcttgcggaaagactcttt
gatgaaataatttcgatgatttccggttag
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