Thermogutta terrifontis: THTE_2306
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Entry
THTE_2306 CDS
T05034
Name
(GenBank) Squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
ttf
Thermogutta terrifontis
Pathway
ttf00909
Sesquiterpenoid and triterpenoid biosynthesis
ttf01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
ttf00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
THTE_2306
Enzymes [BR:
ttf01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
THTE_2306
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
THTE_2306
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Motif
Other DBs
NCBI-ProteinID:
ASV74908
UniProt:
A0A286RG14
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Position
2389288..2391249
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AA seq
653 aa
AA seq
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MGEALTVARIERALRSVWDLLVARRLPEGFWRGHLCSSPLATATAISALAVYRQNTSDKA
IFSASPGSLDGAISAGLDYLKKTQQKDGGWGDTERSRSNIATTYLVTAAIHLAGQAGYCE
DVLAAAQAYLRSQGELQGLRNRYGADQTFVAPILTNCAIAGIFPWENVPQLPFELAAFPQ
SVYRFLRMPVVSYAIPALVAVGLARHKKCPSSFPPLRLIRDAVQSRCLQVALKMQPNSGG
YLEAIPLTSFVAMCLCTAGLAHHPITARALDFLLRNQRGDGSWPVDVDLATWLTTLAINA
VHAGRPEETASDVPFGSLVSLDWLARCQWLEIHPFTGAAPGGWGWTDQTGAVPDADDTAG
ALLALCHIWPQISAAERARLWPHVILGLHWLVGLQNRDGGWPTFCRGWGRFPFDRSAVDL
TAHAIRALHGWSKVFEHLDAQAEEVQCLDFSERFSPPLRRFIERLWKRRVVFRERLIQAL
NKGMRFLVNCQAEEGFWLPLWFGNEWLPGEANPVYGTAKCLLAFADLDAHNTDCCRRAVC
WLAGNQNPDGSWGWGFWTDNLPTPGQASYRDHSGSIEETALAVAALSALPHQDGLEARSR
GVMWLVRAVEEGKVTQATPIGLYFARLWYFEELYPLIFTLEALGRYLRSATSN
NT seq
1962 nt
NT seq
+upstream
nt +downstream
nt
atgggtgaagcgttaacggtggctcggatcgaacgagctcttcgatctgtttgggatctg
ttggttgccaggcggttgcccgagggattctggcgtgggcacttgtgctcttcaccacta
gccaccgcaacggccatttccgcgctggcggtttatagacaaaatacgtccgacaaggcg
atcttttccgcgagccctggcagcctggacggggctatttccgcgggtctcgattatctt
aagaaaactcagcaaaaagatgggggttggggggatacggagcgttcccgatctaatatc
gcgacaacctatcttgtcacagcagctatccatctggcgggtcaagcaggatactgcgag
gacgttctggcggcagctcaagcctatctcaggtctcaaggcgaactgcaaggcctgagg
aaccgctacggggctgaccagacgtttgtcgctccgatcctcaccaactgtgcaattgcc
gggatctttccttgggaaaacgtccctcagcttcccttcgaactggcggcgtttccccag
tccgtctaccggtttctcaggatgccggtcgtcagctatgcgattcctgccctggtggcc
gtggggctagcacgccacaaaaaatgtccaagctctttcccgcctcttcggttgattcgc
gacgcagttcaatcacgatgtctccaggttgctttgaaaatgcaaccgaacagcgggggc
tatctggaggccattcctctcacgtcgttcgtggcgatgtgcctttgcacagcgggactg
gcgcatcatccgatcacggcgagggcgttggactttcttcttcggaatcagcgcggagac
gggagctggccggtcgatgttgacctggcaacgtggttgaccacgctcgcaataaatgcg
gtgcatgctggtcggccggaagagacagcgtcagacgtcccgttcggctctcttgtgtcc
ctggattggcttgcgcggtgtcaatggttggagatccacccgttcaccggagctgcacca
ggaggctgggggtggactgatcaaacgggtgcggtaccagatgccgacgatactgctggt
gccctgctggcgctgtgtcacatttggccacaaatcagtgccgcagaaagggcccgcctc
tggccacacgtcattctggggctgcattggctggtgggcctgcagaatcgggatgggggc
tggccaacgttttgtcgtggctggggccgtttcccgtttgaccgcagcgctgtcgatctg
acagcccatgcgattcgggcactccacggttggagcaaagtcttcgagcacttggacgcc
caggcggaggaagttcagtgtctggatttttcagaacgcttttcaccgccgctgcgccgc
ttcattgagcgtctatggaaaaggcgagtcgtgttcagggaacggttgatccaggcgttg
aacaaggggatgcgattcctcgtgaattgtcaagcggaggaaggcttttggttacctctc
tggttcggaaacgagtggcttcccggtgaggctaatcccgtctatggcaccgcgaagtgc
ttacttgcttttgcagacctggatgcccacaatacggattgttgcaggcgggccgtctgc
tggctggctggaaaccagaatcccgatggaagctggggctggggtttctggactgacaat
ctgccaacgccgggccaggcaagttaccgggatcattccggctcgatagaggagacagct
ctcgcggtggcagcgctctctgccctcccacatcaagacgggctcgaggcgcgaagccga
ggagtgatgtggcttgtgcgagccgtggaagaaggaaaagtgactcaggcaacccccatc
ggcctgtattttgccagactttggtactttgaagagctgtatccgctaatttttacgctt
gaggcactgggacggtacctgcggtcggcgaccagtaattag
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