Thermus thermophilus HB8: TTHA0939
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Entry
TTHA0939 CDS
T00220
Symbol
TTHA0939
Name
(GenBank) pyruvate dehydrogenase (lipoamide) (EC 1.2.4.1) E1-alpha chain
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ttj
Thermus thermophilus HB8
Pathway
ttj00010
Glycolysis / Gluconeogenesis
ttj00020
Citrate cycle (TCA cycle)
ttj00620
Pyruvate metabolism
ttj00785
Lipoic acid metabolism
ttj01100
Metabolic pathways
ttj01110
Biosynthesis of secondary metabolites
ttj01120
Microbial metabolism in diverse environments
ttj01200
Carbon metabolism
ttj01210
2-Oxocarboxylic acid metabolism
Module
ttj_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ttj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
TTHA0939 (TTHA0939)
00020 Citrate cycle (TCA cycle)
TTHA0939 (TTHA0939)
00620 Pyruvate metabolism
TTHA0939 (TTHA0939)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TTHA0939 (TTHA0939)
Enzymes [BR:
ttj01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
TTHA0939 (TTHA0939)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
HTH_41
Motif
Other DBs
NCBI-ProteinID:
BAD70762
UniProt:
Q5SJR9
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All DBs
Position
1:complement(886814..887854)
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AA seq
346 aa
AA seq
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MKPKVVRYLDEGEFPLAEEEALRLYRAMRRARFFDEKALTLQRQGRLGVYAPFMGQEAAQ
VGVALALEERDWVVPSYRESAMLLAKGLPIHTLILYWRAHPAGWRFPEGVRAVNPYIPIA
TQIPQAVGLALAGRYRGEDWVVATSIGDGGTSEGDFHEGLNFAAVFGAPVVFLVQNNGYA
ISVPKSRQMKVDYVARRAEGYGMPGVVVDGNDAFAVYLEAKKAVERARKGEGPTLLEALT
YRLAPHTTSDDPSRYRSKEEEEAWRAKDPILRLRKALEGRGLWGEEAEKALLLELEEEFQ
RELALADEAPEPRPEEIVEHVYAEMGPDQRRAWEALRRGLHVEEVE
NT seq
1041 nt
NT seq
+upstream
nt +downstream
nt
gtgaagccgaaggtggtgcggtatctggatgaaggggagttccccctagcggaggaagaa
gccctgaggctctaccgggccatgcgccgggcccggttttttgacgagaaggccctcacc
ctccagcgccaggggaggcttggggtctacgcccccttcatgggccaggaggcggcccag
gtgggggtggccctggccctggaggagagggactgggtcgtcccctcctaccgggaaagc
gccatgctcctcgccaaggggcttcccatccacaccctcatcctctactggcgggcccac
cctgccggctggcgcttccccgagggggtcagggcggtgaacccctacatccccatcgcc
acccagatcccccaggcggtggggctcgccctggccgggcggtaccggggggaggactgg
gtggtggccacctccatcggggacggggggacgagcgagggggacttccacgaggggctg
aacttcgccgcggtcttcggcgcccccgtggtcttcctggtgcagaacaacggctacgcc
atcagcgtccccaaaagccgccagatgaaggtggactacgtggcgaggcgggccgagggg
tacgggatgccgggggtggtggtggacgggaacgacgccttcgccgtgtacctcgaggcc
aagaaggcggtggagagggccaggaagggggagggccccaccctcctcgaggccctcacc
taccgcctcgccccccacaccacctccgacgacccctcccgctaccgcagcaaagaggaa
gaggaagcctggcgggccaaggacccgatcctccgcctgcggaaggccctggaggggcgg
ggcctctggggcgaggaggcggagaaggcgcttcttcttgagcttgaggaggagttccag
agggagctcgccctggccgacgaagcccccgagcccaggcccgaggagatcgtggagcac
gtctacgccgagatgggccccgaccagaggcgggcctgggaggccctcaggcgaggcctc
cacgtggaggaggtggagtga
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