Thermus thermophilus JL-18: TtJL18_0038
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Entry
TtJL18_0038 CDS
T02009
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ttl
Thermus thermophilus JL-18
Pathway
ttl00790
Folate biosynthesis
ttl01100
Metabolic pathways
ttl01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ttl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
TtJL18_0038
Enzymes [BR:
ttl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
TtJL18_0038
6.3.2.17 tetrahydrofolate synthase
TtJL18_0038
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
SfsA_N
Motif
Other DBs
NCBI-ProteinID:
AFH37962
UniProt:
H9ZNQ2
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Position
37407..38651
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AA seq
414 aa
AA seq
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MDPLSWLYARQGRFAPGLERIRALLARLGHPEEAYPVALVGGTNGKGTTARALAAILEEA
GFRVGLYTSPHLVDFRERIQVQGRPIPEEKLLALLAELRLHAERLEASFFEAATALALLH
FAREGVEFAVLEVGLGGRLDATNATEPVLSVVTNVGHDHLEVLGPTLKDVAREKAGIFRG
GVPALTAARGEGLGVLRAEALARKTPLWVLGEDFHAEGVEALPEGLAFTLRLERTGEALR
LTARLLGPHQAENLALAALSGRLLGAGWEAVKRGVARAENPGRLQRLLWRGRELLLDGAH
NPEGALALREALRFHGLLPAAFVLGFSRDKDHAAMAEALRGLGPVVLTRYASPRSEDPKA
LLPLFPGAKVVEDPLEALEEAFSREGRVVVAGSLYLVGEVLRRLEGLPAEERWQ
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atggaccccctctcctggctctacgcccggcagggccgcttcgccccgggcctggagcgg
atccgggccctcctcgcccgcctcggccaccccgaggaggcctatcccgtggccctcgtg
ggggggacgaacgggaagggcaccaccgcccgggccctcgccgccattctggaagaggcg
gggtttagggtgggcctctacaccagcccccacctggtggacttccgggagcgcatccag
gtccagggaaggccgatccccgaggagaagctcctggcgcttttggcggagctccgtctc
catgccgagcgcctggaggcgagcttctttgaggccgctaccgccctcgccctcctccac
ttcgcccgggagggggtggagtttgccgttctcgaggtgggcctgggggggcgcctggac
gccaccaacgctacagagcccgtcctctccgtggtcaccaacgtcggccacgaccacctc
gaggtcctgggccccaccctgaaggacgtggcccgggagaaggcggggatcttccgcggg
ggcgtccccgccctcaccgccgcccggggggaggggcttggggttttgcgggccgaggcc
ttggcccgcaagacccccttgtgggtcctgggggaggacttccacgccgagggggtggag
gctctgcccgagggcctcgccttcaccctgcgcctggagaggacgggggaggccctgagg
cttaccgcccgcctcctcggcccccaccaggcggagaacctggccctggccgccctttcg
ggccgcctccttggggcgggctgggaggcggtgaagcggggcgtggcccgggcggaaaac
ccggggaggctccagcggcttctttggcgagggagggagctccttctggacggggcccac
aacccggagggggccttggccctgagggaggccctgcgcttccacggtctgcttcccgcc
gccttcgtcctcggtttcagccgcgacaaggaccacgccgccatggccgaggccctgagg
ggcttgggccccgtggtcctcacccgctacgcctccccgagaagcgaggaccccaaggcc
ctccttcccctcttcccgggggccaaggtggtggaggaccccctcgaggccctggaggag
gccttctcccgggaaggccgggtggtggtggcaggaagcctctacctggtgggggaggtt
ctccgccgccttgaggggcttcccgccgaggagcggtggcagtag
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